Tribology of piston skirt conjunction

Frictional losses in the piston skirt to cylinder liner conjunction account for approximately 2.5% of the energy supplied to the modern car [1]. These losses are contributed by viscous shear of the lubricant and asperity interactions on the contiguous surfaces. However, for most of the piston cycle the regime of lubrication is dominated by elastohydrodynamics or hydrodynamics. Hence, friction due to viscous shear is dominant. Most idealistic analyses employ a “cold” piston skirt shape and use either a measured profile or by approximated polynomials as the input shape [2-4]. In reality, however, pistons are subject, not only to contact forces, but also thermo-mechanical distortion. These are as the result of thermal expansion of the piston as well as its global mechanical deformation in situ. They alter the pistonliner conjunctional gap. The piston structure is designed in such a way as to prevent gross localised wear in service by means of skirt profile and structural stiffness modification [5]. Considering the combined effect of global as well as local deformation of the skirt under the influence of contact force, it is vital to take into account the effect of shape and rigidity of both the piston and liner structures in an integrated thermoelastic and elastohydrodynamic analysis. This approach is more representative of the in situ “hot” skirt condition as noted by McClure [6]. This paper shows the significant differences observed in the generated pressures, film thickness and friction by comparing “cold” piston profiles; disregarding large scale global deformation and “hot” thermo-elastically deformed skirt conjunctions with representative skirt stiffness

The influence of piston ring geometry and topography on friction

This article provides solution for isothermal mixed hydrodynamic conjunction of the compression ring to cylinder liner. This is obtained using the average flow model representation of Reynolds equation based on pressure- and shear-induced flow factors. In particular, the effects of compression ring axial profile along its face-width and surface topography of contiguous solids are investigated. It is shown that ring geometry may be optimized to improve lubrication, whilst care should be taken in order to avoid oil loss or degradation resulting from any loss of sealing. In predicting friction, it is shown that appropriate surface parameters should be used in-line with the state of wear of the ring. For a new ring against a plateau honed liner, boundary friction contribution during the initial running-in wear phase should be predicted according to the average asperity peak heights protruding above the plateau, whilst the plateau height also takes into account the valleys within the surface roughness or grooves created by any cross-hatch honing would be the appropriate measure of topography for worn rings. The main contributions of the article are in providing an analytic solution as well investigation of ring face-width geometry and effect of wear upon friction. However, it is acknowledged that generated heat, inlet boundary starvation and circumferential non-conformity of ring to the bore surface would affect the film thickness and exacerbate generated friction accordingly. These further considerations would require a numerical solution, rather than an analytical one presented here

Acute inhibition of MEK suppresses congenital melanocytic nevus syndrome in a murine model driven by activated NRAS and Wnt signaling

Congenital melanocytic nevus (CMN) syndrome is the association of pigmented melanocytic nevi with extra-cutaneous features, classically melanotic cells within the central nervous system, most frequently caused by a mutation of NRAS codon 61. This condition is currently untreatable and carries a significant risk of melanoma within the skin, brain, or leptomeninges. We have previously proposed a key role for Wnt signaling in the formation of melanocytic nevi, suggesting that activated Wnt signaling may be synergistic with activated NRAS in the pathogenesis of CMN syndrome. Some familial pre-disposition suggests a germ-line contribution to CMN syndrome, as does variability of neurological phenotypes in individuals with similar cutaneous phenotypes. Accordingly, we performed exome sequencing of germ-line DNA from patients with CMN to reveal rare or undescribed Wnt-signaling alterations. A murine model harboring activated NRASQ61K and Wnt signaling in melanocytes exhibited striking features of CMN syndrome, in particular neurological involvement. In the first model of treatment for this condition, these congenital, and previously assumed permanent, features were profoundly suppressed by acute post-natal treatment with a MEK inhibitor. These data suggest that activated NRAS and aberrant Wnt signaling conspire to drive CMN syndrome. Post-natal MEK inhibition is a potential candidate therapy for patients with this debilitating condition

A SUSY SU(5) Grand Unified Model of Tri-Bimaximal Mixing from A4

We discuss a grand unified model based on SUSY SU(5) in extra dimensions and on the flavour group A4xU(1) which, besides reproducing tri-bimaximal mixing for neutrinos with the accuracy required by the data, also leads to a natural description of the observed pattern of quark masses and mixings.Comment: 19 page

First-principles Calculation of the Formation Energy in MgO-CaO Solid Solutions

The electronic structure and total energy were calculated for ordered and disordered MgO-CaO solid solutions within the multiple scattering theory in real space and the local density approximation. Based on the dependence of the total energy on the unit cell volume the equilibrium lattice parameter and formation energy were determined for different solution compositions. The formation energy of the solid solutions is found to be positive that is in agreement with the experimental phase diagram, which shows a miscibility gap.Comment: 11 pages, 3 figure

Linguistic and statistically derived features for cause of death prediction from verbal autopsy text

Automatic Text Classification (ATC) is an emerging technology with economic importance given the unprecedented growth of text data. This paper reports on work in progress to develop methods for predicting Cause of Death from Verbal Autopsy (VA) documents recommended for use in low-income countries by the World Health Organisation. VA documents contain both coded data and open narrative. The task is formulated as a Text Classification problem and explores various combinations of linguistic and statistical approaches to determine how these may improve on the standard bag-of-words approach using a dataset of over 6400 VA documents that were manually annotated with cause of death. We demonstrate that a significant improvement of prediction accuracy can be obtained through a novel combination of statistical and linguistic features derived from the VA text. The paper explores the methods by which ATC may leads to improved accuracy in Cause of Death prediction

The fermi arc and fermi pocket in cuprates in a short-range diagonal stripe phase

In this paper we studied the fermi arc and the fermi pocket in cuprates in a short-range diagonal stripe phase with wave vectors $(7\pi/8, 7\pi/8)$, which reproduce with a high accuracy the positions and sizes of the fermi arc and fermi pocket and the superstructure in cuprates observed by Meng et al\cite{Meng}. The low-energy spectral function indicates that the fermi pocket results from the main band and the shadow band at the fermi energy. Above the fermi energy the shadow band gradually departs away from the main band, leaving a fermi arc. Thus we conclude that the fermi arc and fermi pocket can be fully attributed to the stripe phase but has nothing to do with pairing. Incorporating a d-wave pairing potential in the stripe phase the spectral weight in the antinodal region is removed, leaving a clean fermi pocket in the nodal region.Comment: 5 pages, 6 figure

A systematic review of physical activity promotion strategies

This article was first published in:British Journal of Sports Medicine:1996:30:84-89We have reviewed randomised controlled trials of physical activity promotion to provide recent and reliable information on the effectiveness of physical activity promotion. Computerised databases and references of references were searched. Experts were contacted and asked for information about existing work. Studies assessed were randomised controlled trials of healthy, free living, adult subjects, where exercise behaviour was the dependent variable. Eleven trials were identified. No United Kingdom based studies were found. Interventions that encourage walking and do not require attendance at a facility are most likely to lead to sustainable increases in overall physical activity. Brisk walking has the greatest potential for increasing overall activity levels of a sedentary population and meeting current public health recommendations. The small number of trials limits the strength of any conclusions and highlights the need for more research

The mass-to-light ratio of rich star clusters

We point out a strong time-evolution of the mass-to-light conversion factor eta commonly used to estimate masses of unresolved star clusters from observed cluster spectro-photometric measures. We present a series of gas-dynamical models coupled with the Cambridge stellar evolution tracks to compute line-of-sight velocity dispersions and half-light radii weighted by the luminosity. We explore a range of initial conditions, varying in turn the cluster mass and/or density, and the stellar population's IMF. We find that eta, and hence the estimated cluster mass, may increase by factors as large as 3 over time-scales of 50 million years. We apply these results to an hypothetic cluster mass distribution function (d.f.) and show that the d.f. shape may be strongly affected at the low-mass end by this effect. Fitting truncated isothermal (Michie-King) models to the projected light profile leads to over-estimates of the concentration parameter c of delta c ~ 0.3 compared to the same functional fit applied to the projected mass density.Comment: 6 pages, 2 figures, to appear in the proceedings of the "Young massive star clusters", Granada, Spain, September 200

Weight and age at weaning influence pancreatic size and enzymatic capacity

Many pig producers are moving towards early weaning in an effort to minimise disease transfer from sow to piglet. However, it is possible that the digestive function of early-weaned pigs may be immature and incapable of digesting many feedstuffs. The present study was designed to examine some of the factors that might influence pancreatic enzymic function in the weaned pig