Changing cultural pathways through gender role and sexual development: A theoretical framework

Greenfield's theory linking sociodemographic change to dynamic cultural values for family interdependence versus individual independence is applied to sexual and gender role socialization and development. The theory explains how cultural pathways for sexual and gender-role development transform in concert with sociodemographic changes: urbanization, formal schooling, capitalism, and communication technologies. As environments become more urban, commercial, and technological, with more opportunities for formal education, sexual development moves away from the ideals of procreation and family responsibility and toward the ideals of personal pleasure and personal responsibility. At the same time, gender-role development moves away from the ideals of complementary and ascribed gender roles and toward chosen and equal gender roles. We present psychological, anthropological, and sociological evidence for these trends in a variety of communities undergoing social and ecological change. © 2014 by the American Anthropological Association

Some identities on derangement and degenerate derangement polynomials

In combinatorics, a derangement is a permutation that has no fixed points. The number of derangements of an n-element set is called the n-th derangement number. In this paper, as natural companions to derangement numbers and degenerate versions of the companions we introduce derangement polynomials and degenerate derangement polynomials. We give some of their properties, recurrence relations and identities for those polynomials which are related to some special numbers and polynomials.Comment: 12 page

A centralised cloud services repository (CCSR) framework for optimal cloud service advertisement discovery from heterogenous web portals

© 2013 IEEE. A cloud service marketplace is the first point for a consumer to discovery, select and possible composition of different services. Although there are some private cloud service marketplaces, such as Microsoft Azure, that allow consumers to search service advertainment belonging to a given vendor. However, due to an increase in the number of cloud service advertisement, a consumer needs to find related services across the worldwide web (WWW). A consumer mostly uses a search engine such as Google, Bing, for the service advertisement discovery. However, these search engines are insufficient in retrieving related cloud services advertainments on time. There is a need for a framework that effectively and efficiently discovery of the related service advertisement for ordinary users. This paper addresses the issue by proposing a user-friendly harvester and a centralised cloud service repository framework. The proposed Centralised Cloud Service Repository (CCSR) framework has two modules - Harvesting as-a-Service (HaaS) and the service repository module. The HaaS module allows users to extract real-time data from the web and make it available to different file format without the need to write any code. The service repository module provides a centralised cloud service repository that enables a consumer for efficient and effective cloud service discovery. We validate and demonstrate the suitability of our framework by comparing its efficiency and feasibility with three widely used open-source harvesters. From the evaluative result, we observe that when we harvest a large number of services advertisements, the HaaS is more efficient compared with the traditional harvesting tools. Our cloud services advertisements dataset is publicly available for future research at: http://cloudmarketregistry.com/cloud-market-registry/home.html

Role of Androgens in Female Genitourinary Tissue Structure and Function: Implications in the Genitourinary Syndrome of Menopause.

Abstract Introduction Genitourinary conditions in women increase in prevalence with age. Androgens are prerequisite hormones of estrogen biosynthesis, are produced in larger amounts than estrogens in women, and decrease throughout adulthood. However, research and treatment for genitourinary complaints have traditionally focused on estrogens to the exclusion of other potential hormonal influences. Aim To summarize and evaluate the evidence that androgens are important for maintaining genitourinary health in women and that lack of androgenic activity can contribute to the development of symptoms of the genitourinary syndrome of menopause. Methods The role of androgens in the pathophysiology, diagnosis, and treatment of genitourinary syndrome of menopause was discussed by an international and multidisciplinary panel during a consensus conference organized by the International Society for the Study of Women's Sexual Health. A subgroup further examined publications from the PubMed database, giving preference to clinical studies or to basic science studies in human tissues. Main Outcome Measures Expert opinion evaluating trophic and functional effects of androgens, their differences from estrogenic effects, and regulation of androgen and estrogen receptor expression in female genitourinary tissues. Results Androgen receptors have been detected throughout the genitourinary system using immunohistochemical, western blot, ligand binding, and gene expression analyses. Lower circulating testosterone and estradiol concentrations and various genitourinary conditions have been associated with differential expression of androgen and estrogen receptors. Supplementation of androgen and/or estrogen in postmenopausal women (local administration) or in ovariectomized animals (systemic administration) induces tissue-specific responses that include changes in androgen and estrogen receptor expression, cell growth, mucin production, collagen turnover, increased perfusion, and neurotransmitter synthesis. Conclusion Androgens contribute to the maintenance of genitourinary tissue structure and function. The effects of androgens can be distinct from those of estrogens or can complement estrogenic action. Androgen-mediated processes might be involved in the full or partial resolution of genitourinary syndrome of menopause symptoms in women. Traish AM, Vignozzi L, Simon JA, et al. Role of Androgens in Female Genitourinary Tissue Structure and Function: Implications in the Genitourinary Syndrome of Menopause. Sex Med Rev 2018;6:558–571

Trust and influence in the Gulf of Mexico's fishery public management network

© 2019 by the authors. Sustainable fishery management is a complex multi-sectoral challenge requiring substantial interagency coordination, collaboration, and knowledge sharing. While scholars of public management network theory and natural resource management have identified trust as one of the key ideational network properties that facilitates such interaction, relatively few studies have operationalized and measured the multiple dimensions of trust and their influence on collaboration. This article presents the results of an exploratory study examining the Gulf of Mexico fishery management network comprised of more than 30 stakeholder organizations. Using an empirically validated survey instrument, the distribution of four types of trust, three gradations of influence, and the degree of formality and informality in actor communications were assessed across the fishery public management network. The analysis reveals generally low levels of interorganizational procedural trust and a high degree of network fragmentation along the international border. Civil servants based at U.S. organizations reported nearly no interactions with Mexican agencies, and vice versa. Rational (calculative) trust was the most important in bringing about reported change in other organizations, while dispositional distrust and affnitive (relational) trust also had significant effects. The results suggest that, although transactional interorganizational relationships prevail in Gulf of Mexico fishery governance, well-developed professional relationships contribute meaningfully to the reported success of public fishery network management and warrants further policy attention in order to help ensure sustainability

How do people type on mobile devices? Observations from a study with 37,000 volunteers

© 2019 Association for Computing Machinery. This paper presents a large-scale dataset on mobile text entry collected via a web-based transcription task performed by 37,370 volunteers. The average typing speed was 36.2 WPM with 2.3% uncorrected errors. The scale of the data enables powerful statistical analyses on the correlation between typing performance and various factors, such as demographics, finger usage, and use of intelligent text entry techniques. We report effects of age and finger usage on performance that correspond to previous studies. We also find evidence of relationships between performance and use of intelligent text entry techniques: auto-correct usage correlates positively with entry rates, whereas word prediction usage has a negative correlation. To aid further work on modeling, machine learning and design improvements in mobile text entry, we make the code and dataset openly available

Riociguat for the treatment of chronic thromboembolic pulmonary hypertension.

BACKGROUND: Riociguat, a member of a new class of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studies to be beneficial in the treatment of chronic thromboembolic pulmonary hypertension. METHODS: In this phase 3, multicenter, randomized, double-blind, placebo-controlled study, we randomly assigned 261 patients with inoperable chronic thromboembolic pulmonary hypertension or persistent or recurrent pulmonary hypertension after pulmonary endarterectomy to receive placebo or riociguat. The primary end point was the change from baseline to the end of week 16 in the distance walked in 6 minutes. Secondary end points included changes from baseline in pulmonary vascular resistance, N-terminal pro-brain natriuretic peptide (NT-proBNP) level, World Health Organization (WHO) functional class, time to clinical worsening, Borg dyspnea score, quality-of-life variables, and safety. RESULTS: By week 16, the 6-minute walk distance had increased by a mean of 39 m in the riociguat group, as compared with a mean decrease of 6 m in the placebo group (least-squares mean difference, 46 m; 95% confidence interval [CI], 25 to 67; P<0.001). Pulmonary vascular resistance decreased by 226 dyn · sec · cm-5in the riociguat group and increased by 23 dyn · sec · cm-5in the placebo group (least-squares mean difference, -246 dyn · sec · cm-5; 95% CI, -303 to -190; P<0.001). Riociguat was also associated with significant improvements in the NT-proBNP level (P<0.001) and WHO functional class (P = 0.003). The most common serious adverse events were right ventricular failure (in 3% of patients in each group) and syncope (in 2% of the riociguat group and in 3% of the placebo group). CONCLUSIONS: Riociguat significantly improved exercise capacity and pulmonary vascular resistance in patients with chronic thromboembolic pulmonary hypertension. (Funded by Bayer HealthCare; CHEST-1 and CHEST-2 ClinicalTrials.gov numbers, NCT00855465 and NCT00910429, respectively.) Copyright © 2013 Massachusetts Medical Society

Network-Level Structural Abnormalities of Cerebral Cortex in Type 1 Diabetes Mellitus

Type 1 diabetes mellitus (T1DM) usually begins in childhood and adolescence and causes lifelong damage to several major organs including the brain. Despite increasing evidence of T1DM-induced structural deficits in cortical regions implicated in higher cognitive and emotional functions, little is known whether and how the structural connectivity between these regions is altered in the T1DM brain. Using inter-regional covariance of cortical thickness measurements from high-resolution T1-weighted magnetic resonance data, we examined the topological organizations of cortical structural networks in 81 T1DM patients and 38 healthy subjects. We found a relative absence of hierarchically high-level hubs in the prefrontal lobe of T1DM patients, which suggests ineffective top-down control of the prefrontal cortex in T1DM. Furthermore, inter-network connections between the strategic/executive control system and systems subserving other cortical functions including language and mnemonic/emotional processing were also less integrated in T1DM patients than in healthy individuals. The current results provide structural evidence for T1DM-related dysfunctional cortical organization, which specifically underlie the top-down cognitive control of language, memory, and emotion. © 2013 Lyoo et al