Ispitivanje premaza primjenjenih na diskove kočnica na dva uloška za disk-kočnicu

While braking, according to the severity of it, thermal, metallurgical, constructive and tribological occurrences emerge on the brake disc-pad interface. In this study, NiCr was sprayed as bonding layer onto the discs, one of which was coated with Al2O3-TiO2 by plasma spray and the other was coated with NiCr-Cr3C2 by High Velocity Oxygen Fuel (HVOF). In addition, the discs were tested with inertia dynamometer according to SAE’s J2522 testing procedure. The measurements showed that although the pads of the coated discs were exposed to higher braking temperatures, friction coefficient of the disc coated with NiCr- Cr3C2 was obtained 6 % higher compared to the original disc.Pri kočenju, zbog jačine, dolazi do termalnih, metalurških, konstruktivnih i triboloških pojava na sučelju uloška za disk kočnice. U ovoj analizi, na diskove je poprskan NiCr kao vezni sloj, od kojih je jedan disk premazan plazma sprejem Al2O3-TiO2, a drugi je premazan s NiCr- Cr3C2 pod visokim kisikovim tlakom (VKT). Osim toga, diskovi su testirani dinamometrom inercije prema postupku testiranja SAE J2522. Mjerenja su pokazala da iako su ulošci premazanih diskova bili izloženi visokim temperaturama kočenja, dobiven je 6 % viši koeficijent trenja diska premazanog s NiCr-Cr3C2 u usporedbi s originalnim diskom

Investigation of the coatings applied onto brake discs on disc-brake pad pair

While braking, according to the severity of it, thermal, metallurgical, constructive and tribological occurrences emerge on the brake disc-pad interface. In this study, NiCr was sprayed as bonding layer onto the discs, one ofwhich was coated with Al2O3-TiO2 by plasma spray and the other was coated with NiCr-Cr3C2 by High Velocity Oxygen Fuel (HVOF). In addition, the discs were tested with inertia dynamometer according to SAE’s J2522 testing procedure. The measurements showed that although the pads of the coated discs were exposed to higher braking temperatures, friction coefficient of the disc coated with NiCr- Cr3C2 was obtained 6 % higher compared to the original disc

Assessment of novel biomarkers: STREM-1, pentraxin-3 and pro-adrenomedullin in the early diagnosis of neonatal early onset sepsis

BACKGROUND: Early onset bacterial sepsis in neonates (EOS) is recognized as an important health condition. Early diagnosis is crucial. However, blood culture results are released in 48-72 hours. Many biomarkers have been investigated but none have been accepted as the gold standard. This study aimed to investigate the diagnostic value of the molecules: soluble form of triggering receptor expressed on myeloid cells-1 (sTREM-1), pentraxin-3 (PTX-3) and pro adrenomedullin (pro-ADM) in EOS and compare with currently used biomarkers. METHODS: In this multicenter prospective study, patients were enrolled from different NICUs around the Turkey. Patient data were collected via web-based registry system from attending centers. Neonates, hospitalized with a suspicion of EOS were enrolled. Blood culture and routine blood tests were collected and a serum sample was obtained and kept in-80°C for studying the molecules. According to laboratory results, patients were divided into three groups as; proven sepsis, clinical sepsis and control group. Groups were compared in terms of demographic, clinical and laboratory findings. The primary outcome of the study was to assess any difference between groups in terms of the diagnostic value of the markers aforementioned. RESULTS: A total of 130 patients were enrolled; proven sepsis (n = 36), clinical sepsis (n = 53) and control (n = 41) groups. Groups were similar in terms of demographic findings; mean WBC (P = 0.445), procalcitonin (PCT) (P = 0.083) and IL-6 (P = 0.814) levels. Mean C-reactive protein (CRP) level was significantly higher in clinical sepsis and proven sepsis groups compared to control group (P 0.001). Mean PTX-3 (P = 0.547), pro-ADM (P = 0.766) and sTREM-1 (P = 0.838) levels were similar between groups. CONCLUSION: These promising molecules failed to help in early diagnosis of EOS. Their relation to correlation with disease progression may make more sense as they seem to be expressed in higher amounts with the progression of the disease in previous studies. CRP was the most frequently used biomarker for detecting the sepsis in our study population. © 2020-IOS Press and the authors. All rights reserved

Decrements In The Thrombin Activatable Fibrinolysis Inhibitor (Tafi) Levels In Association With Orlistat Treatment In Obesity

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Membranous nephropathy in Schimke immuno-osseous dysplasia

Schimke immuno-osseous dysplasia is a rare autosomal recessive multi-system disorder, with clinical features of growth retardation, spondylo-epiphyseal dysplasia, nephrotic syndrome and immunodeficiency beginning in childhood. Here, we report a new case, in a 10-year-old boy with characteristic symptoms of Schimke immuno-osseous dysplasia. The patient presented with short stature and, later, developed nephrotic syndrome and peritonitis. In addition, he had perinuclear anti-neutrophilic cytoplasmic antibody (p-ANCA)-positive arthritis. Renal pathology of the patients with this disease usually show focal segmental glomerulonephritis, whereas our patient had membranous nephropathy, which has not previously been reported