712 research outputs found
Effect of adult thymectomy on tumour immunity in mice.
The effect of adult thymectomy in DBA/2J mice on the in vitro response to syngeneic tumour cells was investigated. Spleen cells from adult mice which had been thymectomized 8 weeks previously demonstrated a severely impaired primary cytotoxic response to P815 tumour cells, whereas their cytotoxic responses to allogeneic cells (C57BL/6) and to non-H-2 antigens (BALB/c), and their ability to form a primary antibody response to sheep red blood cells was unimpaired. Suppressor T cells, specific for P815 cells, appeared early in the thymuses of animals inoculated with P815 cells (between 4 and 8 days after tumour-cell injection). No differences in tumour growth between animals thymectomized as adults and sham-operated controls were observed, and thymectomized tumour-bearing animals had levels of specific suppressor cells in their lymph nodes equivalent to the levels found in untreated controls. Severely thymocyte-deprived animals which had been thymectomized, irradiated and reconstituted with either marrow or spleen cells 8 weeks before tumour implantation succumbed more rapidly to metastatic tumour than did control animals
Analytical Results and Conceptual Model of Mine Drainage at the Holden Mine, Chelan County, Washington
Investigations of three, four, and five-particle exit channels of levels in light nuclei created using a 9C beam
The interactions of a E/A=70-MeV 9C beam with a Be target was used to
populate levels in Be, B, and C isotopes which undergo decay into many-particle
exit channels. The decay products were detected in the HiRA array and the level
energies were identified from their invariant mass. Correlations between the
decay products were examined to deduce the nature of the decays, specifically
to what extent all the fragments were created in one prompt step or whether the
disintegration proceeded in a sequential fashion through long-lived
intermediate states. In the latter case, information on the spin of the level
was also obtained. Of particular interest is the 5-body decay of the 8C ground
state which was found to disintegrate in two steps of two-proton decay passing
through the 6Beg.s. intermediate state. The isobaric analog of 8Cg.s. in 8B was
also found to undergo two-proton decay to the isobaric analog of 6Beg.s. in
6Li. A 9.69-MeV state in 10C was found to undergo prompt 4-body decay to the
2p+2alpha exit channel. The two protons were found to have a strong
enhancementin the diproton region and the relative energies of all four p-alpha
pairs were consistent with the 5Lig.s. resonance
Impact of high CO2 on the geochemistry of the coralline algae Lithothamnion glaciale
Coralline algae are a significant component of the benthic ecosystem. Their ability to withstand physical stresses in high energy environments relies on their skeletal structure which is composed of high Mg-calcite. High Mg-calcite is, however, the most soluble form of calcium carbonate and therefore potentially vulnerable to the change in carbonate chemistry resulting from the absorption of anthropogenic CO2 by the ocean. We examine the geochemistry of the cold water coralline alga Lithothamnion glaciale grown under predicted future (year 2050) high pCO2 (589 μatm) using Electron microprobe and NanoSIMS analysis. In the natural and control material, higher Mg calcite forms clear concentric bands around the algal cells. As expected, summer growth has a higher Mg content compared to the winter growth. In contrast, under elevated CO2 no banding of Mg is recognisable and overall Mg concentrations are lower. This reduction in Mg in the carbonate undermines the accuracy of the Mg/Ca ratio as proxy for past temperatures in time intervals with significantly different carbonate chemistry. Fundamentally, the loss of Mg in the calcite may reduce elasticity thereby changing the structural properties, which may affect the ability of L. glaciale to efficiently function as a habitat former in the future ocean
Probing elastic and inelastic breakup contributions to intermediate-energy two-proton removal reactions
The two-proton removal reaction from 28Mg projectiles has been studied at 93
MeV/u at the NSCL. First coincidence measurements of the heavy 26Ne projectile
residues, the removed protons and other light charged particles enabled the
relative cross sections from each of the three possible elastic and inelastic
proton removal mechanisms to be determined. These more final-state-exclusive
measurements are key for further interrogation of these reaction mechanisms and
use of the reaction channel for quantitative spectroscopy of very neutron-rich
nuclei. The relative and absolute yields of the three contributing mechanisms
are compared to reaction model expectations - based on the use of eikonal
dynamics and sd-shell-model structure amplitudes.Comment: Accepted for publication in Physical Review C (Rapid Communication
Elastic breakup cross sections of well-bound nucleons
The 9Be(28Mg,27Na) one-proton removal reaction with a large proton separation
energy of Sp(28Mg)=16.79 MeV is studied at intermediate beam energy.
Coincidences of the bound 27Na residues with protons and other light charged
particles are measured. These data are analyzed to determine the percentage
contributions to the proton removal cross section from the elastic and
inelastic nucleon removal mechanisms. These deduced contributions are compared
with the eikonal reaction model predictions and with the previously measured
data for reactions involving the re- moval of more weakly-bound protons from
lighter nuclei. The role of transitions of the proton between different bound
single-particle configurations upon the elastic breakup cross section is also
quantified in this well-bound case. The measured and calculated elastic breakup
fractions are found to be in good agreement.Comment: Phys. Rev. C 2014 (accepted
Correlations in intermediate-energy two-proton removal reactions
We report final-state-exclusive measurements of the light charged fragments
in coincidence with 26Ne residual nuclei following the direct two-proton
removal from a neutron-rich 28Mg secondary beam. A Dalitz-plot analysis and
comparisons with simulations show that a majority of the triple- coincidence
events with two protons display phase-space correlations consistent with the
(two-body) kinematics of a spatially-correlated pair-removal mechanism. The
fraction of such correlated events, 56(12) %, is consistent with the fraction
of the calculated cross section, 64 %, arising from spin S = 0 two-proton
configurations in the entrance-channel (shell-model) 28Mg ground state wave
function. This result promises access to an additional and more specific probe
of the spin and spatial correlations of valence nucleon pairs in exotic nuclei
produced as fast secondary beams.Comment: accepted for publication in Physical Review Letter
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