Opportunities and Inplementation (A Case Study: Economic Development of Kyaukta Village, Sagaing Township)

The study on economic opportunities is a crucial one not only for economic development but also for all round development of the respective area. In this study, economic opportunities of a village are assessed by means of qualitative method. Due to good location and the given economic opportunities of the study area, people in Kyaukta village know well about different economic opportunities in addition to their traditional farming. By taking an interview to the local residents, the past, present and future economic development pattern could be portrayed systematically. Due to the great efforts of local people in their implementation processes, the different types of economic activities were found within one family. The results show that the economic activities for the individual household could be extracted from the minimum of one in one economic activity to the maximum of five in one household. This situation highlights the greater potentiality of the study area to be developed during the time frame of near future

Design Consideration of Electrical Earthing System for High-rise Building

Electricity is dangerous and required proper grounding to prevent unwanted voltage from passing through personnel, critical equipment and other nearby metallic objects. Soil resistivity directly affects the design of a grounding system. When designing an extensive grounding system it is advisable to locate the area of lowest soil resistivity in order to achieve the economical grounding installation. Neither very low resistivity nor very high resistivity is safe for human safety under power system fault conditions. The earthing or grounding is mainly affected by soil resistivity. This study will briefly explain the earthing of Lightning Protection System for 11th storeyed building. The soil type of this building is loam and soil resitivity is 150 Ωm

Effect of Toposequence Position on Soil Properties and Crop Yield of Paddy Rice in Northern Mountainous Region, Vietnam

Symposium Pape

Spatial differences in soil properties, crop yield and methane emission from paddy rice cascade, Northwest Vietnam

Session 2: Nitrogen, Green House Gasses and Agricultur

Progress Report Integrated Seed Sector Development Myanmar: 2019

This report can also be downloaded from : http://www.d-portal.org

The class II phosphoinositide 3-kinases PI3K-C2α and PI3K-C2β differentially regulate clathrin-dependent pinocytosis in human vascular endothelial cells

金沢大学医薬保健研究域医学系Pinocytosis is an important fundamental cellular process that is used by the cell to transport fluid and solutes. Phosphoinositide 3-kinases (PI3Ks) regulate a diverse array of dynamic membrane events. However, it is not well-understood which PI3K isoforms are involved in specific mechanisms of pinocytosis. We performed knockdown studies of endogenous PI3K isoforms and clathrin heavy chain (CHC) mediated by small interfering RNA (siRNA). The results demonstrated that the class II PI3K PI3K-C2α and PI3K-C2β, but not the class I or III PI3K, were required for pinocytosis, based on an evaluation of fluorescein-5-isothiocyanate (FITC)–dextran uptake in endothelial cells. Pinocytosis was partially dependent on both clathrin and dynamin, and both PI3K-C2α and PI3K-C2β were required for clathrin-mediated—but not clathrin-non-mediated—FITC-dextran uptake at the step leading up to its delivery to early endosomes. Both PI3K-C2α and PI3K-C2β were co-localized with clathrin-coated pits and vesicles. However, PI3K-C2β, but not PI3K-C2α, was highly co-localized with actin filament-associated clathrin-coated structures and required for actin filament formation at the clathrin-coated structures. These results indicate that PI3K-C2α and PI3K-C2β play differential, indispensable roles in clathrin-mediated pinocytosis. © 2018, The Physiological Society of Japan and Springer Japan KK, part of Springer Nature.Embargo Period 12 month

Cancer disparities in Southeast Asia: intersectionality and a call to action.

Southeast Asia has a population of over 680 million people—approximately half the population of India and twice the population of the United States—and is a region marked by rich and complex histories and cultures, dynamic growth, and unique and evolving health challenges.1 Despite the momentum of economic development, health inequalities persist. These inequities have been aggravated since the COVID-19 pandemic, which pushed millions further into poverty, possibly exacerbating health disparities, especially among populations who suffer vulnerabilities.2 Particularly salient are the challenges associated with providing adequate care for people with cancer, a leading cause of morbidity and mortality in the region.1,2 Cancer incidence and mortality in the region are projected to rise in the coming decades, given population growth and rapidly changing socioeconomic and geopolitical factors, as well as a host of interrelated and dynamic environmental, behavioral, and occupational risk factors.1, 2, 3 Large epidemiologic studies have demonstrated differences among Southeast Asian countries in terms of cancer incidence and mortality.3 Epidemiologic patterns can be attributed to variations in complex risk factors, access to screening and cancer care, and likely genetic predisposition.1, 2, 3 However, these differences also underscore that within each country exist richly diverse populations that experience disparities in cancer risk, screening, care access, outcomes, and survivorship in ways that require further examination. We draw attention to disparities in cancer in Southeast Asian countries. We highlight the need to study cancer disparities affecting minoritised groups in Southeast Asia—not only along lines of race/ethnicity, but also people minoritised along lines of sex/gender, socioeconomic status, religion, geography, and others. We highlight the intersectionality of elements of an individual's identity. Intersectionality, developed by critical race theorist Professor Kimberlé Crenshaw in 1989, is an analytic framework borne out of Black American feminist scholarship, that examines how a person's sociopolitical identities lead to disparate balances of privilege and discrimination.4 An intersectional approach would demonstrate that an individual or a community does not only experience economic poverty as the sole barrier to improved health; such an approach would examine how other identities such as religion or immigration status affect access to care. These different social determinants of health are not mutually exclusive; their interrelationships are complex, with consequences for health.5 We leverage the intersectional approach, which parallels the inherently syncretic cultures and histories of Southeast Asian nations, and explore how these identities impact access to cancer care. Meaningful cancer research focusing on peoples of Southeast Asia could present many opportunities for intervention and improvement