Immature stages of Plain Tiger, Danaus chrysippus chrysippus a rare butterfly of Andaman and Nicobar Islands (Insecta: Lepidoptera: Rhopalocera: Danaidae)

The plain Tiger Danaus chrysippus chrysippus (Linnaeus) (Insecta: Lepidoptera: Rhopalocera: Danaidae) is a widely distributed butterfly is rare in Andaman and Nicobar Islands. The scarcity of food plant Calotropis in the islands is the reason for rarity. The immature stages of the butterfly are discussed in the paper with some unusual observations such as laying of eggs in cluster and on the upper side of food plant, showing stress on survival of the fly

Smart Asset Management for Electric Utilities: Big Data and Future

This paper discusses about future challenges in terms of big data and new technologies. Utilities have been collecting data in large amounts but they are hardly utilized because they are huge in amount and also there is uncertainty associated with it. Condition monitoring of assets collects large amounts of data during daily operations. The question arises "How to extract information from large chunk of data?" The concept of "rich data and poor information" is being challenged by big data analytics with advent of machine learning techniques. Along with technological advancements like Internet of Things (IoT), big data analytics will play an important role for electric utilities. In this paper, challenges are answered by pathways and guidelines to make the current asset management practices smarter for the future.Comment: 13 pages, 3 figures, Proceedings of 12th World Congress on Engineering Asset Management (WCEAM) 201

Multicentre observational cohort study of NSAIDs as risk factors for postoperative adverse events in gastrointestinal surgery

Introduction: Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended as postoperative analgesia by the Enhanced Recovery After Surgery Society. Recent studies have raised concerns that NSAID administration following colorectal anastomosis may be associated with increased risk of anastomotic leak. This multicentre study aims to determine NSAIDs' safety profile following gastrointestinal resection. Methods and analysis: This prospective, multicentre cohort study will be performed over a 2-week period utilising a collaborative methodology. Consecutive adults undergoing open or laparoscopic, elective or emergency gastrointestinal resection will be included. The primary end point will be the 30-day morbidity, assessed using the Clavien-Dindo classification. This study will be disseminated through medical student networks, with an anticipated recruitment of at least 900 patients. The study will be powered to detect a 10% increase in complication rates with NSAID use. Ethics and dissemination: Following the Research Ethics Committee Chairperson's review, a formal waiver was received. This study will be registered as a clinical audit or service evaluation at each participating hospital. Dissemination will take place through previously described novel research collaborative networks

Utilization of fish trash for increasing yield and quality of milk in cattle

The difference between cost of milk production and Its telling price Is very thin and Is getting thinner due to cumulative increase in cattle food prices on one side and limitations on marketing price of milk on the other. Possible utilization of trash fish converted to liquid silage a* a part of cattle food resulting In Increased yield of milk and fat concern are discussed in this paper. The development of silage and field trials on milking catties were carried out by Gujarat Fisheries Aquatic Sciences Research Institute, Okha

Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202

CYP17A1 is a key steroidogenic enzyme known to conduct several distinct chemical transformations on multiple substrates. In its hydroxylase activity, this enzyme adds a hydroxyl group at the 17α position of both pregnenolone and progesterone at approximately equal rates. However, the subsequent 17,20 carbon–carbon scission reaction displays variable substrate specificity in the numerous CYP17A1 isozymes operating in vertebrates, manifesting as different Kd and kcat values when presented with 17α-hydroxypregnenlone (OHPREG) versus 17α-hydroxyprogesterone (OHPROG). Here we show that the identity of the residue at position 202 in human CYP17A1, thought to form a hydrogen bond with the A-ring alcohol substituent on the pregnene- nucleus, is a key driver of this enzyme’s native preference for OHPREG. Replacement of asparagine 202 with serine completely reverses the preference of CYP17A1, more than doubling the rate of turnover of the OHPROG to androstenedione reaction and substantially decreasing the rate of formation of dehydroepiandrosterone from OHPREG. In a series of resonance Raman experiments, it was observed that, in contrast with the case for the wild-type protein, in the mutant the 17α alcohol of OHPROG tends to form a H-bond with the proximal rather than terminal oxygen of the oxy–ferrous complex. When OHPREG was a substrate, the mutant enzyme was found to have a H-bonding interaction with the proximal oxygen that is substantially weaker than that of the wild type. These results demonstrate that a single-point mutation in the active site pocket of CYP17A1, even when far from the heme, has profound effects on steroidogenic selectivity in androgen biosynthesis

A Novel Concept for a Positron Emission Tomography Scanner

Positron Emission Tomography (PET) allows physicians and researchers to visualize metabolic data in the human body and is widely used in cancer and neurological imaging. Traditional PET scanners consist of a thin ring of scintillators coupled to photo detectors but these scanners often take long periods of time to acquire an image, are very costly, and are too complex to fit inside other machinery such as MRI. In response to this, we are building a novel PET detector that utilizes non-traditional scintillators and photo detectors in an attempt to significantly decrease cost, allow combined PET/MRI modalities and reduce scan time

CMB Distortions from Superconducting Cosmic Strings

We reconsider the effect of electromagnetic radiation from superconducting strings on cosmic microwave background (CMB) mu- and y-distortions and derive present (COBE-FIRAS) and future (PIXIE) constraints on the string tension, mu_s, and electric current, I. We show that absence of distortions of the CMB in PIXIE will impose strong constraints on mu_s and I, leaving the possibility of light strings (G mu_s < 10^{-18}) or relatively weak currents (I < 10 TeV).Comment: 10pages, 5 figures, Submitted to PRD, v2:References added, replaced to match the PRD versio

Approximate behaviors

The motivation for this paper is to contribute to a unified approach to modeling, realization, approximation and analysis for systems with a rich class of uncertainty structures. The specific focus is on what is the appropriate framework to model components with uncertainty, and what is the appropriate notion of approximation for such components. Components and systems are conceptualized in terms of their behaviors, which can be specified by parametrized equations. More questions are posed than are answered

Determining Specific Window Period for Common Scab Disease Infection in Potato Tubers

A series of experiments was conducted under glasshouse and hydroponic conditions to determine the specific window period for common scab disease infection in potato tubers. The study was performed in a glasshouse system where separate tubers from the root zone were inoculated at different intervals during plant growth along with a novel hydroponic system to inoculate individual tubers at specific times of development growth allowing non-destructive observations of common scab symptoms developing. The window of tuber susceptibility to common scab disease infection was shown to vary with the season or conditions under which the plants were grown. Different internodes on tubers were found susceptible to infection at different times during tuber development. Basal internodes, which are the first sections of the tuber to expand, were susceptible to infection in the beginning of tuber development, whereas apical internodes only became susceptible later in tuber growth when the basal internodes were no longer susceptible.Journal of Nepal Agricultural Research Council Vol.3 2017: 19-2