653 research outputs found

    Dataset from: Lapses in perceptual decisions reflect exploration.

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    Perceptual decision-makers often display a constant rate of errors independent of evidence strength. These “lapses” are treated as a nuisance arising from noise tangential to the decision, e.g. inattention or motor errors. Here, we use a multisensory decision task in rats to demonstrate that these explanations cannot account for lapses’ stimulus dependence. We propose a novel explanation: lapses reflect a strategic trade-off between exploiting known rewarding actions and exploring uncertain ones. We tested the model’s predictions by selectively manipulating one action’s reward magnitude or probability. As uniquely predicted by this model, changes were restricted to lapses associated with that action. Finally, we show that lapses are a powerful tool for assigning decision-related computations to neural structures based on disruption experiments (here, posterior striatum and secondary motor cortex). These results suggest that lapses reflect an integral component of decision-making and are informative about action values in normal and disrupted brain states

    Extrapulmonary Tuberculosis: A retrospective Study at a tertiary care hospital in Palpa, Nepal

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    Background: Extra-pulmonary tuberculosis (EPTB) is a significant global health problem. Related studies to it in different places and diff erent durations are indicated by many previous research findings. Findings of this study could be beneficial for its preventive and control strategies. Methodology: Retrospective analysis of clinical specimens submitted to Central laboratory of Lumbini Medical College and Teaching Hospital (LMCTH) for extrapulmonary tuberculosis was performed. Total 261 samples submitted from April 2011 to February 2013 were included for analysis in this study. Results: Total 20.7% (54/261) prevalence of EPTB was reported. Based on sites involved; lymph node 87.03%, pleural effusion7.40%, peritoneal5.55% were found. Genderwise equal prevalence was seen among male and females. Age-wise prevalence among patients between 21-40 years was reported. Conclusion: Our finding indicates great necessity for further large scale study on prevalence of EPTB in this location for its prevention and control

    Assessment of Yield and Yield Attributing Characters of Hybrid Maize using Nutrient ExpertÂź Maize Model in Eastern Terai of Nepal

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    Indiscriminate use of fertilizer and lack of site specific nutrient management technology is the main cause of low maize productivity in Nepal. Thus, field experiments on farmer\u27s field were conducted on maize to assess the productivity at two sites of Jhapa district viz. Damak and Gauradaha using Nutrient ExpertÂź Maize model from November 2015 to May 2016. The experiment was laid out in Randomized Completely Block Design consisting two treatments viz. NE (Nutrient Expert recommendation) and FFP (Farmer\u27s Fertilizer Practice) with twenty replications. The result revealed significant differences in terms of grain yield, stover yield, biological yield, and yield attributing characters. NE based practices produced higher grain yield (9.22 t ha-1), which was 86.6 percent higher than FFP (4.94 t ha-1). Similarly, higher average cob number m 2 (8.2), average kernel rows cob-1 (14.2), average kernels number row-1 (589.9) and test weight (361.4 g) were recorded in NE based practice. Thus, NE based practice can be adopted for obtaining higher productivity in eastern terai region of Nepal

    Effects of climatic factors on diarrheal diseases among children below 5 years of age at national and subnational levels in Nepal: an ecological study

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    INTRODUCTION: The incidence of diarrhea, a leading cause of morbidity and mortality in low-income countries such as Nepal, is temperature-sensitive, suggesting it could be associated with climate change. With climate change fueled increases in the mean and variability of temperature and precipitation, the incidence of water and food-borne diseases are increasing, particularly in sub-Saharan Africa and South Asia. This national-level ecological study was undertaken to provide evidence linking weather and climate with diarrhea incidence in Nepal. METHOD: We analyzed monthly diarrheal disease count and meteorological data from all districts, spanning 15 eco-development regions of Nepal. Meteorological data and monthly data on diarrheal disease were sourced, respectively, from the Department of Hydrology and Meteorology and Health Management Information System (HMIS) of the Government of Nepal for the period from 2002 to 2014. Time-series log-linear regression models assessed the relationship between maximum temperature, minimum temperature, rainfall, relative humidity, and diarrhea burden. Predictors with p-values < 0.25 were retained in the fitted models. RESULTS: Overall, diarrheal disease incidence in Nepal significantly increased with 1 degrees C increase in mean temperature (4.4%; 95% CI: 3.95, 4.85) and 1 cm increase in rainfall (0.28%; 95% CI: 0.15, 0.41). Seasonal variation of diarrheal incidence was prominent at the national level (11.63% rise in diarrheal cases in summer (95% CI: 4.17, 19.61) and 14.5% decrease in spring (95% CI: -18.81, -10.02) compared to winter season). Moreover, the effects of temperature and rainfall were highest in the mountain region compared to other ecological regions of Nepal. CONCLUSION: Our study provides empirical evidence linking weather factors and diarrheal disease burden in Nepal. This evidence suggests that additional climate change could increase diarrheal disease incidence across the nation. Mountainous regions are more sensitive to climate variability and consequently the burden of diarrheal diseases. These findings can be utilized to allocate necessary resources and envision a weather-based early warning system for the prevention and control of diarrheal diseases in Nepal

    Quasi-normal modes of Schwarzschild-de Sitter black holes

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    The low-laying frequencies of characteristic quasi-normal modes (QNM) of Schwarzschild-de Sitter (SdS) black holes have been calculated for fields of different spin using the 6th-order WKB approximation and the approximation by the P\"{o}shl-Teller potential. The well-known asymptotic formula for large ll is generalized here on a case of the Schwarzchild-de Sitter black hole. In the limit of the near extreme Λ\Lambda term the results given by both methods are in a very good agreement, and in this limit fields of different spin decay with the same rate.Comment: 9 pages, 1 ancillary Mathematica(R) noteboo

    The structure of the extreme Schwarzschild-de Sitter space-time

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    The extreme Schwarzschild-de Sitter space-time is a spherically symmetric solution of Einstein's equations with a cosmological constant Lambda and mass parameter m>0 which is characterized by the condition that 9 Lambda m^2=1. The global structure of this space-time is here analyzed in detail. Conformal and embedding diagrams are constructed, and synchronous coordinates which are suitable for a discussion of the cosmic no-hair conjecture are presented. The permitted geodesic motions are also analyzed. By a careful investigation of the geodesics and the equations of geodesic deviation, it is shown that specific families of observers escape from falling into the singularity and approach nonsingular asymptotic regions which are represented by special "points" in the complete conformal diagram. The redshift of signals emitted by particles which fall into the singularity, as detected by those observers which escape, is also calculated.Comment: 19 pages, 10 figures, LaTeX, to appear in Gen. Rel. Gra

    Poor Thermal Care Practices among Home Births in Nepal: Further Analysis of Nepal Demographic and Health Survey 2011

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    Introduction - Hypothermia is a major factor associated with neonatal mortality in low and middle income countries. Thermal care protection of newborn through a series of measures taken at birth and during the initial days of life is recommended to reduce the hypothermia and associated neonatal mortality. This study aimed to identify the prevalence of and the factors associated with receiving ‘optimum thermal care’ among home born newborns of Nepal. Methods - Data from the Nepal Demographic and Health Surveys (NDHS) 2011 were used for this study. Women who reported a home birth for their most recent childbirth was included in the study. Factors associated with optimum thermal care were examined using Chi-square test followed by logistic regression. Results - A total of 2464 newborns were included in the study. A total of 57.6 % were dried before the placenta was delivered; 60.3% were wrapped; 24.5% had not bathing during the first 24 hours, and 63.9% were breastfed within one hour of birth. Overall, only 248 (10.7%; 95% CI (8.8 %, 12.9%)) newborns received optimum thermal care. Newborns whose mothers had achieved higher education (OR 2.810; 95% CI (1.132, 6.976)), attended four or more antenatal care visits (OR 2.563; 95% CI (1.309, 5.017)), and those whose birth were attended by skilled attendants (OR 2.178; 95% CI (1.428, 3.323)) were likely to receive optimum thermal care. Conclusion - The current study showed that only one in ten newborns in Nepal received optimum thermal care. Future newborn survival programs should focus on those mothers who are uneducated; who do not attend the recommended four or more attend antenatal care visits; and those who deliver without the assistance of skilled birth attendants to reduce the risk of neonatal hypothermia in Nepal
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