Comparison of Ferrous Sulphate with Iron Polymaltose in Treating Iron Deficiency Anaemia in Children

Background: To compare the efficacy of ferrous sulphate vs Iron polymaltose complex for the treatment of iron deficiency anaemia in children. Methods:  In this randomized control trial , 170 children having iron deficiency anaemia with hemoglobin< 10g/dl and serum ferritin levels below 6ng/ml were selected . Patients were randomly allocated into Group A, given Syrup  ferrous sulphate in a dose of 6mg/kg/day of elemental iron once daily for 4 weeks and Group B, given syrup  iron polymaltose complex in a dose of 6mg/kg/day of elemental iron once daily orally for 4 weeks. Results: - The average age was 24.86±17.85 months. The efficacy was significantly high in ferrous sulphate as compare to Iron polymaltose complex for the treatment of iron deficiency anaemia (p=0.009). Conclusion: Ferrous sulphate  has advantage over iron polymaltose complex in treatment of iron deficiency anaemia where rise in haemoglobin was considere

Linearization and Special Asymptotic Behaviour of the Second Painlevé Equation

AbstractLinearization of the initial value problem associated with the special second Painlevé equation is discussed using a different isomonodromic spectral problem than the one used in [1]. Further properties of the monodromy data [2, 3] are detected and these properties are used to reduce the problem to a linear singular integral equation via a Riemann–Hilbert boundary value problem on an imaginary line. A special asymptotic increasing solution of the Painlevé equation is constructed forx→−∞ from the above integral equation. Moreover, failure to extract asymptotics forx→+∞ is also mentioned

Basics of Self Micro Emulsifying Drug Delivery System

About 70-75% of drugs is taken orally and is found not to be as useful as desired. A self-micro emulsifying drug delivery system (SMEDDS) is a drug delivery system that uses a micro-emulsion achieved by chemical rather than mechanical means. Micro-emulsions have significant potential for use in drug delivery, and SMEDDS are the best of these systems. SMEDDS are of particular value in increasing the absorption of lipophilic drugs taken orally. SMEDDS are mixtures  of natural or  synthetic oils,  solid  or  liquid  surfactants, or alternatively, one or more  hydrophilic solvents and  co-solvents/surfactants  that have a unique ability  of  forming fine  oil-in-water (o/w) micro  emulsions  upon mild agitation followed  by  dilution in  aqueous media, such as  GI fluids. SMEDDS spread readily in the GI tract, and the digestive motility of the stomach and the intestine provide the agitation necessary for self-emulsification. SMEDDS can be encapsulated in hard or soft gelatin capsules or can be converted to solid state (Solid SEDDS/SMEDDS). This review article provides an overview of SMEDDS and its advantages over conventional dosage forms. Keywords: SMEDDS, Micro-emulsions, Co-solvent

Employee engagement for sustainable organizations: keyword analysis using social network analysis and burst detection approach

The issue of sustainability is a vital long-term goal for organizations and as such has formed the basis of much academic research over the last two decades. Organizational sustainability is defined as the ability for an organization to accomplish a range of economic, environmental, and human performance objectives. As one of the most studied topics in organizational science, employee engagement at work is seen as a critical component to achieving sustainable organizational success. In order to better understand the employee engagement discourse, this study examined the keywords that appear in the titles and abstract of the employee engagement research domain using the burst detection and social network analysis techniques. A total of 1406 employee engagement relevant articles that were published from 1990 to 2015 were included and investigated in the study. The results revealed the fading, emerging, and central themes within the employee engagement domain

Mathematical Modeling and Review of Pine Wilt Disease

Pine Wilt Disease (PWD), caused by the pinewood nematode (PWN) Bursaphelenchus xylophilus, causes significant losses in coniferous forests in eastern Asia, including Japan, China, and South Korea, as well as western Europe, including Portugal. The results of the research papers given at the International Symposium on Pine Wilt Disease (IUFRO Working Party Meeting 4.04.03) in Nanjing, China, in July 2009 are summarized in this article. The basic themes discussed included pine wilt disease (PWD), the pinewood nematode (PWN) Bursaphelenchus xylophilus, and other PWN-associated microorganisms that play a significant role in PWD, such as bacteria (e.g., Pseudomonas fluorescens). The majority of the papers are based on PWD-PWN research in East Asia and Russia. The following are some of the specific topics covered: 1) fundamental concepts of PWD development, 2) pathogenicity, 3) host-parasite relationships, including histopathology of diseased conifers and the role of toxins from bacteria-nematode ecto-symbionts, 4) PWN life cycle and transmission, 5) B. xylophilus dissemination models, 6) associations (with other nematodes), 7) diagnostics, 8) quarantine and control of the PWN and 9) biocontrol of the PWN

Fabrication, physicochemical characterization and preliminary efficacy evaluation of a W/O/W multiple emulsion loaded with 5% green tea extract

Emulsões múltiplas complexas possuem excelente habilidade de agregar grandes quantidades de agentes cosméticos funcionais. Este estudo teve por objetivo encapsular grandes volumes de chá verde em uma emulsão múltipla clássica e comparar sua estabilidade com a emulsão múltipla sem o extrato do chá verde. Emulsões múltiplas são desenvolvidas usando cetil dimeticona copoliol como emulsificante lipofílico e o clássico polissorbato-80 como emulsificante hidrofílico. As emulsões múltiplas foram avaliadas por meio de vários aspectos fisico-químicos como condutividade, pH, análise microscópica e reologia. Estas características foram observadas por um período de 30 dias sob diferentes condições de armazenamento. Testes de proteção da pele in vivo e in vitro foram realizados para ambos os tipos de emulsões testadas, i.e. com o ativo em estudo (MeA) e sem ativo (MeB). Ambas as formulações apresentaram características comparáveis no que diz respeito aos diferentes fatores físico-químicos avaliados sob diferentes condições de armazenamento. A análise reológica mostrou que as formulações apresentaram comportamento pseudo-plástico sob contínuo estresse de cisalhamento. Os resultados dos testes in vivo e in vitro sobre a proteção da pele revelaram que a formulação ativa promoveu efeitos comparáveis à formulação controle. Nossos dados mostraram que emulsões múltiplas estáveis poderiam ser escolhas promissoras para a aplicação tópica do chá verde. Entretanto, a fórmula das emulsões múltiplas apresentadas neste estudo precisam ser melhoradas no que diz respeito ao pH, condutividade e viscosidade aparente.Complex multiple emulsions have an excellent ability to fill large volumes of functional cosmetic agents. This study was aimed to encapsulate large volume of green tea in classical multiple emulsion and to compare its stability with a multiple emulsion without green tea extract. Multiple emulsions were developed using Cetyl dimethicone copolyol as lipophilic emulsifier and classic polysorbate-80 as hydrophilic emulsifier. Multiple emulsions were evaluated for various physicochemical aspects like conductivity, pH, microscopic analysis, rheology and these characteristics were followed for a period of 30 days in different storage conditions. In vitro and in vivo skin protection tests were also performed for both kinds of multiple emulsions i.e. with active (MeA) and without active (MeB). Both formulations showed comparable characteristics regarding various physicochemical characteristics in different storage conditions. Rheological analysis showed that formulations showed pseudo plastic behavior upon continuous shear stress. Results of in vitro and in vivo skin protection data have revealed that the active formulation has comparable skin protection effects to that of control formulation. It was presumed that stable multiple emulsions could be a promising choice for topical application of green tea but multiple emulsions presented in this study need improvement in the formula, concluded on the basis of pH, conductivity and apparent viscosity data

Formulation and stability of topical water in oil emulsion containing corn silk extract

Purpose: To formulate the water in oil (W/O) emulsion of corn silk (CS) extract and to evaluate its stability at various storage conditions.Methods: Ethanol CS extract was prepared using maceration (cold) technique. A 4 % CS emulsion was prepared using varying concentrations of liquid paraffin, ABIL EM90 and water. The formulations were kept at 25 oC for 28 days and to screen out the less stable formulations. The remaining formulations were further stressed at 40 oC to choose the most stable formulation. The optimized formulation was evaluated for physical characteristics including phase separation, rheology and mean droplet size. The physical stability of the formulation was evaluated by monitoring these parameters over a period of 12 weeks at 8, 25, 40 and 40 oC, and 75 % RH.Results: The chosen formulation showed good resistance to phase separation on centrifugation under all storage conditions. Rheological behavior followed non-Newtonian pseudoplastic pattern at various storage conditions. Mean droplet size of freshly prepared formulation was 2.98 ± 1.32 μm and did not show significant (p < 0.05) changes at normal storage conditions (8 and 25 oC).Conclusion: The findings indicate that the developed CS extract W/O emulsion is stable and therefore may be suitable for topical use on skin as an antioxidant preparation.Keywords: Corn silk, Emulsion, Nonionic surfactant, Rheology, Flow index, Droplet size, Non-Newtonian pseudoplasti

Investigating Pakistani Students' alternative Ideas regarding the Concept of Chemical Bonding

Abstract Acknowledgement of prior students' conceptions by science teacher has proved a significant tool for effective science teaching/learning. So the major objective of this research study is to investigate students' alternative ideas (misconceptions) and to develop an understanding about the existence of high frequencies of alternative ideas among science students at secondary level. A random sample of 120 students of 10 th class was selected to explore student

Peace Education Practices in Pre-Service Teacher Training Programs: and Analysis

This study was designed to investigate peace education in pre-service teacher training programs in Khyber Pakhtunkhwa, Pakistan. The objectives of the present study to find out :( a) to examine prevailing practices of peace education in pre-service teacher training programs in Khyber Pakhtunkhwa Pakistan. (b) To evaluate the views of teacher Educators regarding the need of peace education in pre-service teacher training programs in Khyber Pakhtunkhwa Pakistan. (c) To suggest way of integrating peace education in pre-service teacher training programs in Khyber Pakhtunkhwa Pakistan. Using Survey method the data were collected through questionnaire from 245 teachers using simple random technique. A questionnaire was developed to investigate the opinions of the participants of the study. The data was analyzed by using the mean score, frequency and percentage

2-(4-Acetamido­benzene­sulfonamido)­benzoic acid

In the title compound, C15H14N2O5S, two similar mol­ecules comprise the asymmetric unit, which are linked by strong inter­molecular C—H⋯π inter­actions. Both mol­ecules are bent, with dihedral angles of 71.94 (16) and 74.62 (15)° between the benzene rings. An intra­molecular N—H⋯O hydrogen bond occurs in each mol­ecule. In the crystal, inter­molecular N—H⋯O and O—H⋯O hydrogen bonds link the mol­ecules into a three-dimensional network