50 research outputs found
Elements of Universal Appeal in the Heroic Characters of Mrs. Warren and Ghasiram Kotwal
In this paper we have gone on to analyze the character of Mrs Warren in Mrs Warren s Profession and Ghasiram Kotwal in the play by the same name Ghasiram Kotwal Both these characters are among some of the strongest ones drawn by George Bernard Shaw and Vijay Tendulkar Both the characters are the strongest characters of George Bernard Shaw and Vijay Tendulkar respectively As Shaw was inspired from a true story of a lead poisoning case of Ms Ann Jane in a white lead factory on the other hand Ghasiram was a historical inspiration from the Maratha history of a man who was in charge of policing in Poona during the reign of Madhav Rao Peshwa under the aegis of the minister Nana Fadnavis The two characters in question are some of the most versatile in terms of the emotional and dramatic hues they carry besides being very pragmatic at times They have a very vivid universal appeal because they are breakers of stereotypes in the most nuanced way These characters show how men and women can transcend from the debate of Masculinity and Feminism when the ambition of men and women is held as the only guiding light to achieve success in lif
Efficacy of the cell block technique in diagnostic cytopathology: comparing immunocytochemistry and cytomorphologic preservation on cell block material with conventional cytological preparations
A dissertation submitted to the Faculty of Health Sciences, University of Witwatersrand,
in fulfilment of the requirements for the degree
of
Master of Science (Medicine) in the branch of Anatomical Pathology
Johannesburg, 2012Objective
To determine the effectiveness of the cell block technique for immunocytochemical
diagnosis by comparing cytomorphologic preservation and immunocytochemistry (ICC)
stains in paired cell block and conventional fine needle aspiration (FNA) samples.
Study Design
This was a prospective study. Material for both conventional smears and cell blocks were
collected simultaneously during fine needle aspiration of 50 lesions comprising lymph
node, lung and liver masses. Grading of cellularity, morphological preservation,
architectural preservation, immunocytochemical staining intensity and presence of
background staining were compared on paired FNA smears and cell block samples
derived from the same case. Each arm of the paired analysis was performed blindly
without knowledge of the grading outcome of the other. The Kappa statistic (Κ) was used
to measure inter-rater agreement.
Results
The fifty samples evaluated included FNAs from the lung, 24/50 (48%); liver, 23/50
(46%) and lymph node, 3/50 (6%). The immunocytochemistry stains consisted of 44/50
(88%) CK7, 44/50 (88%) CK20, 18/50 (36%) TTF1, 10/50 (20%) synaptophysin, 10/50
(20%) Hepar-1 and 7/50 (14%) AE1/3. There was no overall agreement in preservation
of cytomorphological detail and ICC staining between the two methods. The
Papanicolaou stained conventional FNA smears fared better then cell block for the
vi
evaluation of nuclear and cytomorphologic characteristics; cells in the cell block were
poorly preserved in many cases. The ICC stains worked better on the cell block samples
due to lack of background and aberrant staining.
Conclusion
Conventional FNA smears and cell blocks complement each other. Our results indicate
that it would be optimal to use both modalities in the diagnostic work-up of mass lesions
amenable to FNA diagnosis; the former to assess morphology, and the latter for optimal
immunocytochemistry results. In resource constrained settings, the cost implications of
performing both conventional and blocked smears on all FNA material warrants further
evaluation
Determinants of Internal Migration in Pakistan: Evidence from the Labour Force Survey, 1996-97
The process of migration has diverse economic, social and environmental implications for the places of origin and destination. In the context of balanced regional growth and sustainable regional development it is important to study how internal migration affects the patterns of population distribution within a country. The spatial distribution of population is influenced by the characteristics of the sending and receiving areas in terms of push and pull factors resulting in rural-urban, urban-urban, rural-rural and urban-rural migration flows. As economies transform from being predominantly rural to being predominantly urban societies, the process of urbanisation assumes a rapid pace. Individuals migrate from rural to urban areas as a rational human capital investment decision to reap economic rewards in the form of better economic opportunities and benefits. The consequences of rapid urbanisation are multi faceted and require timely responses by development planners and policy-makers to deal with pressures created on the infrastructure of large urban centres by the influx of migrants. However, in some developing as well as developed countries, lately, there have been signs of a change in the trend of the population distribution away from concentration in a few large cities towards a more widespread distribution in medium-sized urban centres. The other dimension of this rural-urban migrant outflow manifests itself in the changing labour market scenario in the rural economy which loses the more productive members of its labour force to the urban economy.
Determinants of Internal Migration in Pakistan: Evidence from the Labour Force Survey, 1996-97
The process of migration has diverse economic, social and
environmental implications for the places of origin and destination. In
the context of balanced regional growth and sustainable regional
development it is important to study how internal migration affects the
patterns of population distribution within a country. The spatial
distribution of population is influenced by the characteristics of the
sending and receiving areas in terms of push and pull factors resulting
in rural-urban, urban-urban, rural-rural and urban-rural migration
flows. As economies transform from being predominantly rural to being
predominantly urban societies, the process of urbanisation assumes a
rapid pace. Individuals migrate from rural to urban areas as a rational
human capital investment decision to reap economic rewards in the form
of better economic opportunities and benefits. The consequences of rapid
urbanisation are multi faceted and require timely responses by
development planners and policy-makers to deal with pressures created on
the infrastructure of large urban centres by the influx of migrants.
However, in some developing as well as developed countries, lately,
there have been signs of a change in the trend of the population
distribution away from concentration in a few large cities towards a
more widespread distribution in medium-sized urban centres. The other
dimension of this rural-urban migrant outflow manifests itself in the
changing labour market scenario in the rural economy which loses the
more productive members of its labour force to the urban
economy
Immunofluorescence laser micro-dissection of specific nephron segments in the mouse kidney allows targeted downstream proteomic analysis
Laser micro-dissection (LMD) is a very useful tool that allows the isolation of finite areas from tissue specimens for downstream analysis of RNA and protein. Although LMD has been adapted for use in kidney tissue, the use of this powerful tool has been limited by the diminished ability to identify specific tubular segments in the kidney. In this study, we describe a major improvement in the methodology to isolate specific cells in the mouse kidney using immunofluorescence LMD (IF-LMD). Using IF-LMD, we can reproducibly isolate not only glomeruli, but also S1-S2 proximal segments, S3 tubules, and thick ascending limbs. We also demonstrate the utility of a novel rapid immunofluorescence staining technique, and provide downstream applications for IF-LMD such as real-time PCR and cutting-edge proteomic studies. This technical breakthrough may become an invaluable tool for understanding cellular and molecular events in the heterogeneous kidney milieu
Is More Nutrition Education Needed in the Undergraduate Medical Curriculum? : Perceptions of graduates from a medical university in the United Arab Emirates
Objectives: The rise in lifestyle diseases has resulted in primary physicians advising more patients on the benefits of nutritional modifications. However, nutrition education has remained more or less unchanged in the undergraduate medical curriculum. This study aimed to assess the perceptions of medical graduates regarding nutrition education in their undergraduate curriculum. Methods: A total of 125 medical graduates from the Gulf Medical University in Ajman, United Arab Emirates, were invited to participate in an anonymous online survey from May to October 2012. The validated pilot-tested questionnaire was designed to assess perceptions regarding nutrition education in the undergraduate medical curriculum. Results:A total of 65 medical graduates responded to the survey, of which 55% were female. Of the respondents, 32% were general physicians and 68% were specialists in various disciplines. Nutrition education was perceived to be very important by 80% of the respondents; however, 78.5% felt that they had not received adequate instruction in this field during their undergraduate medical curriculum. The major areas of deficit identified were in the categories of clinical nutrition, nutrition in primary care and evidence-based nutrition. Conclusion: In this study, Gulf Medical University graduates perceived a need for more nutrition-related instruction in their undergraduate medical curriculum. The areas of deficit identified in this study could help in future curricular improvements.Keywords:
The future physicians of United Arab Emirates: how do they self-medicate?
Background: Health professions have been a predictive factor for self-medication (SM). SM practices of medical students, the future practitioners will have a bearing on their impending professional practice. The aims were to identify prevalence and practice of SM among the medical students of Gulf Medical University (GMU), United Arab Emirates and to assess the associating factors.Methods: The study was planned as a cross-sectional descriptive survey among 247 medical students of GMU. Students from 1st to 5th year were included in the study. Data were analyzed using SPSS version 19. Associations were tested with Chi-square test.Results: SM with both over-the-counter medications and prescription-only medicines was practiced by 65% of students. The prevalence of SM was associated with the year of study and age. The most common sources of drugs were private pharmacies and stocks at home. The students mostly relied on themselves and parents for drug selection. The self-reliance significantly increased with year of study. Common indications for SM were headache and flu symptoms and correspondingly, analgesics and antipyretics were frequently used. A high prevalence of misuse of antibiotics was also reported. SM was 2.9 times higher (95% CI=1.502-5.620) among students belonging to families practicing SM.Conclusion: The study revealed a fairly high rate of prevalence of SM among the medical students of GMU, which was associated with age and year of study. There is a need to emphasize responsible SM practices among the medical students by accentuating rational drug use in the curricula
Linguistic based Movements for separation in South Asian States: A Case Study of Sri Lanka
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The effect of linguistic is the integral part of the Social and political consideration in the multi-linguistic countries all over the World. South Asian countries are facing multi-linguistic problem and as a result separation movements exist in the region since decades. However, each state/country is confronting this issue according to its environment and local circumstances. This paper will focus the impacts of ethnicity on education and poverty in Sri Lanka. The existence of India, Pakistan and Bangladesh is one of the major reasons of linguistic issue. In case of Sri Lanka, the Tamil movement though could not succeed due to various reasons but originally initiated due to linguistic deprivation of Tamil community. The main reasons are not only language but the deprivation in education, employment and social status like poverty of particular community. If their problems are addressed properly then the linguistic issue cannot be highlighted. It is worth mentioning that all the linguistic based separation movement succeeded if supported by the International community otherwise failed. The good examples are Tamil and Khalistan separation movements. In addition to above, the Sri Lankan government took advantage of 9/11 incident and crushed the movement with force and international community remained silent. As a result this linguistic based separation movement could not succeeded in Sri Lanka despite the fact that these kind of movements succeeded in South Asia.
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Diabetes Mellitus-Related Knowledge among University Students in Ajman, United Arab Emirates
The aim of this study was to assess diabetes mellitus (DM)-related knowledge and practices among university students enrolled in non-health care related professional courses in the United Arab Emirates. Methods: A pre-tested questionnaire assessing the knowledge of DM was administered to the above-mentioned students. Data collected were transferred to PASW Statistics (Chicago, IL, USA, Version 18) and analysed. Results: Data on 168 university students (47 males and 121 females) were included in the analysis. Of the participants, 25% were overweight or obese and only 27% exercised regularly. Regarding their knowledge of DM, 70% knew that it is characterised by high blood sugar levels and identified family history as a major risk factor. Surprisingly, only just over half could link obesity and physical inactivity as risk factors for developing DM, or could identify an excessive feeling of thirst, frequent urination, and weight loss as symptoms. Knowledge of the complications of diabetes, including gangrene, loss of sensation in limbs, oral and dental complications, recurrent infections, and risk for cardiovascular disease got a moderate response. Knowledge of diabetes was found to be higher in females compared to males. No significant differences were observed in the health behaviour of participants with or without a family history of DM. Conclusion: Our study revealed that in spite of exposure to various sources of information, the participants’ level of DM-related knowledge was not adequate. We recommend the engagement of health professionals in educational settings in order to enhance health-related knowledge and inculcate healthy lifestyle practices in students.
Factors associated with self-medication among expatriate high school students: a cross-sectional survey in United Arab Emirates
The study aimed to assess factors associated with self-medication (SM) among expatriate high school students of United Arab Emirates using a validated questionnaire. Most common reasons for self-medication in 324 participating students were: presence of mild illness and previous experiences. High risk practices like altering the dose, discontinuation of medication and self-medication without adult guidance were observed. The likelihood of SM was 4.9 times (95%C.I.: 2.0-12.2) in students not utilizing private healthcare services than those who were utilizing these services. Increased efforts are needed to prevent the risks of self-medication in adolescents through healthcare education for both parents and adolescents