84 research outputs found

    Pharmacological correction of L-NAME-induced oxide deficiency with derivatives of 3-(2,2,2-trimethylhydrazinium) propionate

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    This paper deals with the study of correction of L-NAME-induced endothelial dysfunction by means of 3-(2,2,2-trimethylhydrazinium) propionate derivative

    Study of dose-dependent effect of 2-ethyl-6-methyl-3 hydroxypyridine succinate on the contractile function of isolated rat heat

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    In experiments on the isolated rat heart there were studied the effects of different doses (21.43 mg/kg/day and 85 . 72 mg/kg/day) 2-ethyl-6-methyl-3 hydroxypy ridine succinate ("EkoPharmInvest", Russia), on the contractile function of isolated hearts subjected to prior doxorubicin model (20 mg/kg, intraperitoneal) of pathology. The dynamic of the power mechanisms of ion transport was evaluated by imposing high h eart rate (480 BPM) and increase concentration of Са2+ to 5 mmol in perfusat

    Synthesis of 2,3-dimethyl-6,7-benzo-5,9-(1′,2′-indano)-2-azabicyclo[3.3.1]non-6-ene

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    A structural analog of morphinan- 2,3-dimethyl-6,7-benzo-5,9-(1′,2′-indano)-2-azabicyclo-[3.3.1]non-6-ene -was synthesized from 3-methyl-2-azafluorene. © 1974 Consultants Bureau, a division of Plenum Publishing Corporation
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