2,552 research outputs found
Drainage Considerations and Stormwater Structure Rehabilitation
Throughout the United States there are millions of culverts that have exceeded their design life. Some of these antique structures were built by stone masons and craftsmen over 100 years ago, while others were installed using common materials that have rusted or crumbled over time. This presentation will address common drainage considerations, the factors that lead to culvert deterioration, and considerations for utilizing rehabilitation methods for long-term service and preservation
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A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support.
Giant cell myocarditis is a rare but often devastating diagnosis. Advances in cardiac imaging and mechanical circulatory support have led to earlier and more frequent diagnoses and successful management. This disease state has wide variation in acuity of presentation, and consequently, optimal treatment ranging from intensity and type of immunosuppression to mechanical circulatory support is not well defined. The following case describes the management of a patient with an unusual presentation of giant cell myocarditis over a 10 year course of advanced heart failure therapies and immunomodulatory support. This case highlights emerging concepts in the management of giant cell myocarditis including sub-acute presentations, challenges in diagnosis, and treatment modalities in the modern era
A GPU Implementation for Two-Dimensional Shallow Water Modeling
In this paper, we present a GPU implementation of a two-dimensional shallow
water model. Water simulations are useful for modeling floods, river/reservoir
behavior, and dam break scenarios. Our GPU implementation shows vast
performance improvements over the original Fortran implementation. By taking
advantage of the GPU, researchers and engineers will be able to study water
systems more efficiently and in greater detail.Comment: 9 pages, 1 figur
Effect of peroxynitrite (ONOO−) on the function of murine perivascular adipose tissue
Perivascular adipose tissue (PVAT) surrounds the exterior of blood vessels and releases numerous substances such as adiponectin which positively modulate blood vessel tone. In some cardiovascular diseases such as diabetes and high blood pressure, the function of PVAT changes and we speculated that oxidant stress may play a role in this change. PVAT has the ability to generate both superoxide and nitric oxide and these can combine rapidly under physiological conditions to form peroxynitrite (ONOO-). In disease states, the production of ONOO- may be increased and so its effect on the function of PVAT is of great interest. Consequently, we studied the effects of acute addition of the oxidant species ONOO- on vascular tone and production of adiponectin by mouse thoracic aortic PVAT. Murine PVAT immunostained for nitrotyrosine, indicating that ONOO- is formed in the PVAT. Exogenous ONOO- significantly increased the anticontractile effect of PVAT via increased adiponectin content but had no effect on eNOS expression or phosphorylation. These results suggest that generation of ONOO- within PVAT may be an important regulatory mechanism which influences the activity of PVAT. The effect of chronic exposure to raised levels of ONOO- on PVAT function remains to be determined
CARS (College Awareness of Road Safety) Project: the Redesign of a Dublin City Centre Junction With Respect to Non-Vehicular Traffic Between the Ages of 17-24.
Impact of Technology Readiness and Techno Stress on Teacher Engagement in Higher Secondary Schools
Rapid technology advancements resulted a fundamental shift in the education sector which redefined the teaching-learning process and teacher engagement. Based on numerous studies on work engagement models and technology readiness, this study explores, how the teachers’ readiness to embrace educational technologies, impact on teacher engagement. With stratified cluster sampling model, data were collected from principals, managers, students and 122 faulty were participated in this quantitative study using standardized tools. Teachers were highly engaged with students-colleagues and varied across experience/age groups. Technology readiness factors positively impacted on social engagements with students-colleagues. As education technology usage is exponential, more future research is needed
Analysis of Loads Paths in Residential Houses
The Moore tornado on May 20th 2013 caused severe damage to numerous residential homes. A research team was sent to rate the damage and collect information about load paths during tornadic events. The team found that the load paths of the houses were insufficient and that failure was occurring in the connections. Using the information they collected a relationship between the center line of the tornado path and EF rating could be seen. This could be used to see how and where the failure occurs. In addition to a statistical analysis a theoretical analysis was also done to support the information from the research team. This analysis also included the comparison of nailed and metal connection to see the benefit they provide.Civil & Environmental Engineerin
Self-selected walking speeds as a function of load in reproductive age women carrying an indigenous pack basket.
Keywords: Women, locomotion, loads
Almost universally, females from indigenous populations walk long distances carrying heavy loads; these loads include infants and toddlers, food, water, firewood, and household belongings. The purpose of our research was to determine how different levels of load carried in an indigenous pack basket affect the speeds selected by free-walking reproductive age women given qualitative speed directives. The study involved 14 women between 18 and 30 y who were in the luteal phase of their menstrual cycle or taking oral contraceptives. Subjects carried three different load amounts in an indigenous style pack basket -- 0 kg (an empty pack), 10 kg, and 20 kg -- while walking around a gym perimeter at four different walking speed directives (“slow walk”, “walk all day”, “brisk walk”, “fast walk”). During each of two testing days, 12 trials (all combinations of 3 loads, 4 speed directives) were performed in a random order. Each trial consisted of six minutes walking followed by four minutes resting. Average selected walking speed for each trial was determined from video tape recordings on each side of the gym. Actual walking speed increased curvilinearly with speed directive. For a given speed directive, selected speeds dropped significantly from 0 to 20 kg loads at all but the “slow walk” directive, with the amount of the speed drop increasing at faster speed directives. Such load-related modulation of walking speed could limit daily foraging range, as well as increase the frequency of camp moves, potentially influencing the mobility of the entire population
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