A Comprehensive Examination of Clinical Cutoff Scores for the Inventory of Callous-Unemotional Traits (ICU)

Youth with elevated callous-unemotional (CU) traits represent a clinically important subgroup of youth who display particularly severe conduct problems and antisocial behavior and thusly impose great costs to themselves, other individuals, and society. The recent addition of the specifier for CU traits, “with Limited Prosocial Emotions (LPE),” to major classification systems has prompted the need for comprehensive and valid assessment tools that aid in the identification of these traits. One such tool is a multi-informant questionnaire, the Inventory of Callous-Unemotional Traits (ICU). However, a major limitation of this measure is a lack of well-validated cutoff scores. With this, the present study compared the clinical utility of various proposed cutoff methods and scores (i.e., empirically derived cutoffs using receiver operating characteristic (ROC), normative cutoffs, and four-item approximations of LPE criteria) in both a longitudinal sample of justice-involved adolescents (N = 1,216; Mage = 15.29, SD = 1.29) and a cross-sectional sample of community youth (N = 289; Mage = 11.47 years; SD = 2.26). A series of chi-square and independent-samples T-tests were conducted with the use of clinically important validators (e.g., juvenile delinquency, social rejection), and average effect sizes were computed. As a result, comparisons of clinical utility are made and a range of optimal cutoff scores, for each ICU informant version, are provided for the detection of elevated CU traits. The outcomes of this study have important practical implications as they provide researchers and clinicians with guidance on choosing cutoffs that may aid in determining elevations of CU traits

The Effect of Dietary Patterns & Mental State

The most common forms of mental disorder treatment include therapy, medication and physical activity. However, it is not quite as common to look at dietary habits to improve mental health. An anonymous online survey was administered through a google form. The survey included questions on the individuals general demographic, diet parameters, and various aspects of their mental health and mood states. There is an association between positive mood states and a healthy dietary pattern. Through the results that were obtained via the survey, it is concluded that there is a correlation between a healthy, balanced diet and a positive mental state.https://orb.binghamton.edu/research_days_posters_2023/1041/thumbnail.jp

Characteristics of antidepressant medication users in a cohort of mid-age and older Australians

OBJECTIVES: We aimed to investigate antidepressant use, including the class of antidepressant, in mid-age and older Australians according to sociodemographic, lifestyle and physical and mental health-related factors. METHODS: Baseline questionnaire data on 111,705 concession card holders aged ⩾45 years from the 45 and Up Study—a population-based cohort study from New South Wales, Australia—were linked to administrative pharmaceutical data. Current- and any-antidepressant users were those dispensed medications with Anatomical Therapeutic Chemical classification codes beginning N06A, within ⩽6 months and ⩽19 months before baseline, respectively; non-users had no antidepressants dispensed ⩽19 months before baseline. Multinomial logistic regression was used to calculate adjusted relative risk ratios (aRRRs) for predominantly self-reported factors in relation to antidepressant use. RESULTS: Some 19% of the study population (15% of males and 23% of females) were dispensed at least one antidepressant during the study period; 40% of participants used selective serotonin reuptake inhibitors (SSRIs) only and 32% used tricyclic antidepressants (TCAs) only. Current antidepressant use was markedly higher in those reporting: severe versus no physical impairment (aRRR 3.86(95%CI 3.67–4.06)); fair/poor versus excellent/very good self-rated health (4.04(3.83–4.25)); high/very high versus low psychological distress (7.22(6.81–7.66)); ever- versus never-diagnosis of depression by a doctor (18.85(17.95–19.79)); low-dose antipsychotic use versus no antipsychotic use (12.26(9.85–15.27)); and dispensing of ⩾10 versus <5 other medications (5.97(5.62–6.34)). Sociodemographic and lifestyle factors were also associated with use, although to a lesser extent. Females, older people, those with lower education and those with poorer health were more likely to be current antidepressant users than non-users and were also more likely to use TCAs-only versus SSRIs-only. CONCLUSIONS: Use of antidepressants is substantially higher in those with physical ill-health and in those reporting a range of adverse mental health measures. In addition, sociodemographic factors, including sex, age and education were also associated with antidepressant use and the class of antidepressant used.Emily Banks and Bryan Rodgers are supported by the NHMRC (Fellowship No. 1042717 and 471429, respectively). This project was supported by the Study of Economic and Environmental Factors in health project, funded by the National Health and Medical Research Council of Australia (NHMRC) (grant reference: 402810) and NHMRC project grant 1024450

A Latent Profile Analysis of Affective Triggers for Risky and Impulsive Behavior

Common theoretical models of risky and impulsive behaviors suggest that individuals engage in risky behavior to avoid negative affect or enhance positive affect. However, little research has been done to identify person-centered affective profiles of risky and impulsive behavior, and delineate the individual differences across these profiles. The present study used the Risky, Impulsive, and Self-destructive Behavior Questionnaire in community (N = 439) and incarcerated (N = 262) samples to examine latent affect profiles for risky and impulsive behavior. Four affective profiles emerged: low avoidance and low approach, average avoidance and average approach, high avoidance, and high approach. Conditional probability correlations revealed meaningful differences across these profiles in psychiatric symptomatology, personality characteristics, and behavior. Consideration of affective triggers provides an important framework for dissociating the underlying reasons why individuals engage in risky behavior

Mental Well-Being in UK Higher Education During Covid-19: Do Students Trust Universities and the Government?

This paper draws upon the concept of recreancy to examine the mental well-being of university students during the Covid-19 pandemic. Briefly, recreancy is loss of societal trust that results when institutional actors can no longer be counted on to perform their responsibilities. Our study of mental well-being and recreancy focuses on the role of universities and government regulators within the education sector. We surveyed 600 UK students attending 161 different public higher education providers in October 2020 during a time when many UK students were isolated in their residences and engaged in online learning. We assessed student well-being using the Short Warwick-Edinburgh Mental Well-being Scale (scored 7–35) and found the mean score to be 19.9 [95% confidence interval (CI) 19.6, 20.2]. This level of well-being indicates that a significant proportion of UK students face low levels of mental well-being. Structural equation modeling (SEM) analysis indicates that high recreancy—measured as a low trust in universities and the government—is associated with low levels of mental well-being across the student sample. While these findings are suggestive, they are also important and we suggest that government and university leaders should not only work to increase food and housing security during the Covid-19 pandemic, but also consider how to combat various sector trends that might intensify recreancy

Mortality of native and invasive ladybirds co-infected by ectoparasitic and entomopathogenic fungi

Harmonia axyridis is an invasive alien ladybird in North America and Europe. Studies show that multiple natural enemies are using Ha. axyridis as a new host. However, thus far, no research has been undertaken to study the effects of simultaneous infection by multiple natural enemies on Ha. axyridis. We hypothesized that high thallus densities of the ectoparasitic fungus Hesperomyces virescens on a ladybird weaken the host's defenses, thereby making it more susceptible to infection by other natural enemies. We examined mortality of the North American-native Olla nu-nigrum and Ha. axyridis co-infected with He. virescens and an entomopathogenic fungus-either Beauveria bassiana or Metarhizium brunneum. Laboratory assays revealed that He. virescens- infected O. nu-nigrum individuals are more susceptible to entomopathogenic fungi, but Ha. axyridis does not suffer the same effects. This is in line with the enemy release hypothesis, which predicts that invasive alien species in new geographic areas experience reduced regulatory effects from natural enemies compared to native species. Considering our results, we can ask how He. virescens affects survival when confronted by other pathogens that previously had little impact on Ha. axyridis

Influence of enzyme immobilization and skin-sensor interface on non-invasive glucose determination from interstitial fluid obtained by magnetohydrodynamic extraction

We integrated a magnetohydrodynamic fluid extractor with an amperometric glucose biosensor to develop a wearable device for non-invasive glucose monitoring. Reproducible fluid extraction through the skin and efficient transport of the extracted fluid to the biosensor surface are prerequisites for non-invasive glucose monitoring. We optimized the enzyme immobilization and the interface layer between the sensing device and the skin. The monitoring device was evaluated by extracting fluid through porcine skin followed by glucose detection at the biosensor. The biosensor featured a screen-printed layer of Prussian Blue that was coated with a layer containing glucose oxidase. Both physical entrapment of glucose oxidase in chitosan and tethering of glucose oxidase to electrospun nanofibers were evaluated. Binding of glucose oxidase to nanofibers under mild conditions provided a stable biosensor with analytical performance suitable for accurate detection of micromolar concentrations of glucose. Hydrogels of varying thickness (95-2000 mu m) as well as a thin (30 mu m) nanofibrous polycaprolactone mat were studied as an interface layer between the biosensor and the skin. The effect of mass transfer phenomena at the biosensor-skin interface on the analytical performance of the biosensor was evaluated. The sensing device detected glucose extracted through porcine skin with an apparent (overall) sensitivity of-0.8 mA/(M.cm(2)), compared to a sensitivity of-17 mA/(M.cm(2)) for measurement in solution. The amperometric response of the biosensor correlated with the glucose concentration in the fluid that had been extracted through porcine skin with the magnetohydrodynamic technique.Peer reviewe