Design, development, and fabrication of a prototype ice pack heat sink subsystem. Potassium bifluoride/water solution investigations

A series of investigations was conducted to characterize the physical properties of potassium bifluoride and water solutions for use as the fusible heat sink material in a regenerable portable life support system

Commitments to Give-if-you-Win Exceed Donations After a Win

Should fundraisers ask a banker to donate “if he earns a bonus” or wait and ask after the bonus is known? Standard EU theory predicts these are equivalent; loss-aversion and signaling models predict a larger commitment before the bonus is known; theories of affect predict the reverse. In five experiments incorporating lab and field elements (N=1363), we solicited donations from small lottery winnings , varying the conditionality of donations between participants. Overall, we find conditional donations (“if you win”) exceeded ex-post donations. This represents the first evidence on how pro-social behavior extends to conditional commitments over uncertain income, with implications for charitable fundraising, giving pledges, and experimental methodologyWe would like to thank the Universities of Essex, Düsseldorf, Mannheim and Bonn for providing financial support for our research

Personnel and Organization Development in an R & D Matrix Overlay Operation

Increasingly, R&D companies are finding it desirable to adopt a matrixoverlay 11 organization structure to accomplish project goals on a timely and efficient basis. In shifting from a straight functional organization to a combined functional/project form, some key changes must be made in responsibilities of Program Managers and managers of engineering Capabilities Centers/ 1 New standards of performance and means for reward and advancement under the revised organization structure must be developed. Diverse management and social science experience are called upon in planning and implementing the matrix-overlay structure through the development of such standards

Specificity Between Lactobacilli And Hymenopteran Hosts Is The Exception Rather Than The Rule

Lactobacilli (Lactobacillales: Lactobacillaceae) are well known for their roles in food fermentation, as probiotics, and in human health, but they can also be dominant members of the microbiota of some species of Hymenoptera (ants, bees, and wasps). Honey bees and bumble bees associate with host-specific lactobacilli, and some evidence suggests that these lactobacilli are important for bee health. Social transmission helps maintain associations between these bees and their respective microbiota. To determine whether lactobacilli associated with social hymenopteran hosts are generally host specific, we gathered publicly available Lactobacillus 16S rRNA gene sequences, along with Lactobacillus sequences from 454 pyrosequencing surveys of six other hymenopteran species (three sweat bees and three ants). We determined the comparative secondary structural models of 16S rRNA, which allowed us to accurately align the entire 16S rRNA gene, including fast-evolving regions. BLAST searches and maximum-likelihood phylogenetic reconstructions confirmed that honey and bumble bees have host-specific Lactobacillus associates. Regardless of colony size or within-colony oral sharing of food (trophallaxis), sweat bees and ants associate with lactobacilli that are closely related to those found in vertebrate hosts or in diverse environments. Why honey and bumble bees associate with host-specific lactobacilli while other social Hymenoptera do not remains an open question. Lactobacilli are known to inhibit the growth of other microbes and can be beneficial whether they are coevolved with their host or are recruited by the host from environmental sources through mechanisms of partner choice.National Science Foundation PRFB-1003133, DEB-0919519Texas Higher Education Coordinating Board 01923, National Institutes of Health GM067317Integrative BiologyCellular and Molecular BiologyCenter for Computational Biology and BioinformaticsBrackenridge Field Laborator

Improvement of lung preservation - From experiment to clinical practice

Background. Reperfusion injury represents a severe early complication following lung transplantation. Among the pathogenetic factors, the high potassium content of Euro-Collins(R) solution is discussed. Material and Methods: In a pig model of orthotopic left-sided lung transplantation we investigated the effect of Euro-Collins solution (EC: n=6) versus low potassium dextran (LPD: Perfadex(R): n = 6). Sham-operated (n = 6) animals served as control. Transplant function, cellular energy metabolism and endothelial morphology served as parameters. In a clinical investigation, 124 patients were evaluated following single (EC: n = 31; LPD n = 37) or double (EC: n = 17; LPD n = 39) lung transplantation, whose organs where preserved with EC (n = 48) or LPD (n = 76). Duration of ischemia, duration of ventilation and stay on ICU were registered. Primary transplant function was evaluated according to AaDO(2) values. Cause of early death (30 days) was declared. Results: Experimental results: After flush with EC and 18 h ischemia, a reduction of tissue ATP content (p < 0.01 vs inital value and LPD) was noted. Endothelial damage after ischemia was severe (p < 0.05 vs control), paO(2) was significantly decreased. Clinical results: In the LPD group, duration of ischemia was longer for the grafts transplanted first (SLTx and DLTx: p = 0.0009) as well as second (2. organ DLTx: p = 0.045). Primary transplant function was improved (day 0: SLTx: p = 0.0015; DLTx: p = 0.0095, both vs EC). Duration of ventilation and stay on ICU were shorter (n.s.). Reperfusion injury-associated death was reduced from 8% (EC) to 0 (LPD). Conclusion: In experimental lung preservation, LPD lead to an improved graft function. These results were confirmed in clinical lung transplantation. Clinical lung preservation, therefore, should be carried out by use of LPD. Copyright (C) 2002 S. Karger AG, Basel

New optical polarization measurements of the Crab pulsar

The Crab nebula and its pulsar have been observed for about 3 hours with the high-speed photo-polarimeter OPTIMA in January 2002 at the Calar Alto 3.5m telescope. The Crab pulsar intensity and polarization are determined at all phases of rotation with higher statistical accuracy than ever. Therefore, we were able to separate the so-called 'off-pulse' phase emission (with an intensity of about 1.2% compared to the main peak, assumed to be present at all phases) from the pulsed emission and show the 'net' polarization of the pulsed structures. Recent theoretical results indicate that the measured optical polarization of the Crab pulsar is similar to expectations from a two-pole caustic emission model or a striped pulsar wind model.Comment: AIP Conference Proceedings "Astrophysical Sources of High Energy Particles and Radiation", eds. T. Bulik et al. (NY:AIP), Volume 801, 2005, pp. 306-31

She Even Walked the Dog : The Roles of Relational Context and Goal-Setting in a Welfare to Work Program

This report summarizes an evaluation of the effectiveness of a welfare-to-work program that is operated by the Montachusett Opportunity Council (MOC) in Central Massachusetts. The study looks at how effective the program was in helping clients achieve goals towards self-sufficiency and tries to understand the particulars of the trusting relationships between staff and clients that provided the base from which they worked to address multiple concerns impeding family financial self-sufficiency

Processing and Transmission of Information

Contains reports on three research projects