Anatexis, cooling, and kinematics during orogenesis: Miocene development of the Himalayan metamorphic core, east-central Nepal

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Genomic Surveillance of SARS-CoV-2 in Healthcare Workers: A Critical Sentinel Group for Monitoring the SARS-CoV-2 Variant Shift

SARS-CoV-2 genome surveillance is important for monitoring risk groups and health workers as well as data on new cases and mortality rate due to COVID-19. We characterized the circulation of SARS-CoV-2 variants from May 2021 to April 2022 in the state of Santa Catarina, southern Brazil, and evaluated the similarity between variants present in the population and healthcare workers (HCW). A total of 5291 sequenced genomes demonstrated the circulation of 55 strains and four variants of concern (Alpha, Delta, Gamma and Omicron—sublineages BA.1 and BA.2). The number of cases was relatively low in May 2021, but the number of deaths was higher with the Gamma variant. There was a significant increase in both numbers between December 2021 and February 2022, peaking in mid-January 2022, when the Omicron variant dominated. After May 2021, two distinct variant groups (Delta and Omicron) were observed, equally distributed among the five Santa Catarina mesoregions. Moreover, from November 2021 to February 2022, similar variant profiles between HCW and the general population were observed, and a quicker shift from Delta to Omicron in HCW than in the general population. This demonstrates the importance of HCW as a sentinel group for monitoring disease trends in the general population

Variáveis individuais e familiares na psoríase: um estudo com doentes e parceiros

Este trabalho avalia morbilidade, qualidade de vida, ajustamento de casal, coping familiar e imagem corporal em 101 doentes com psoríase e 78 parceiros. Os resultados revelaram uma relação positiva entre as variáveis dos doentes e parceiros no que diz respeito ao ajustamento, coping e morbilidade. Pior qualidade de vida e imagem corporal no doente estão associadas a mais morbilidade no parceiro. Os doentes em tratamento combinado e fototerapia apresentaram pior qualidade de vida e insatisfação com a imagem corporal. Melhor ajustamento de casal e menor ansiedade no parceiro predizem ajustamento de casal no doente. Satisfação com a imagem corporal prevê melhor qualidade de vida no doente. Os resultados enfatizam a necessidade de envolver os parceiros nos programas de intervenção. As implicações são apresentadas