Extending the MINLO method

We consider improving POWHEG+MINLO simulations, so as to also render them NLO accurate in the description of observables receiving contributions from events with lower parton multiplicity than present in their underlying NLO calculation. On a conceptual level we follow the strategy of the so-called MINLO' programs. Whereas the existing MINLO' framework requires explicit analytic input from higher order resummation, here we derive an effective numerical approximation to these ingredients, by imposing unitarity. This offers a way of extending the MINLO' method to more complex processes, complementary to the known route which uses explicit computations of high-accuracy resummation inputs. Specifically, we have focused on Higgs-plus-two-jet production (HJJ) and related processes. We also consider how one can cover three units of multiplicity at NLO accuracy, i.e. we consider how the HJJ-MINLO simulation may yield NLO accuracy for inclusive H, HJ, and HJJ quantities. We perform a feasibility study assessing the potential of these ideas.Comment: 66 pages, 22 figures; v2 references added; v3=JHEP, improved readabilit

Knowledge-based system V and V in the Space Station Freedom program

Knowledge Based Systems (KBS's) are expected to be heavily used in the Space Station Freedom Program (SSFP). Although SSFP Verification and Validation (V&V) requirements are based on the latest state-of-the-practice in software engineering technology, they may be insufficient for Knowledge Based Systems (KBS's); it is widely stated that there are differences in both approach and execution between KBS V&V and conventional software V&V. In order to better understand this issue, we have surveyed and/or interviewed developers from sixty expert system projects in order to understand the differences and difficulties in KBS V&V. We have used this survey results to analyze the SSFP V&V requirements for conventional software in order to determine which specific requirements are inappropriate for KBS V&V and why they are inappropriate. Further work will result in a set of recommendations that can be used either as guidelines for applying conventional software V&V requirements to KBS's or as modifications to extend the existing SSFP conventional software V&V requirements to include KBS requirements. The results of this work are significant to many projects, in addition to SSFP, which will involve KBS's

Preparing millennials as digital citizens and socially and environmentally responsible business professionals in a socially irresponsible climate

As of 2015, a millennial born in the 1990's became the largest population in the workplace and are still growing. Studies indicate that a millennial is tech savvy but lag in the exercise of digital responsibility. In addition, they are passive towards environmental sustainability and fail to grasp the importance of social responsibility. This paper provides a review of such findings relating to business communications educators in their classrooms. The literature should enable the development of a millennial as an excellent global citizen through business communications curricula that emphasizes digital citizenship, environmental sustainability and social responsibility. The impetus for this work is to provide guidance in the development of courses and teaching strategies customized to the development of each millennial as a digital, environmental and socially responsible global citizen

Finite quark-mass effects in the NNLOPS POWHEG+MiNLO Higgs generator

We include finite top- and bottom-mass effects in the next-to-next-to-leading order parton shower (NNLOPS) event generator for inclusive Higgs boson production in gluon fusion based upon the POWHEG+MiNLO approach. Since fixed-order results for quark-mass effects only reach NLO accuracy, we add them to the NNLOPS generator at that accuracy. We explore uncertainties related to the unknown all-order logarithmic structure of bottom-mass effects by comparing the assumption of full exponentiation to no exponentiation at all. Phenomenological results showing the effects of finite quark-masses in the NNLOPS simulation are presented. These suggest that the aforementioned uncertainty is well contained within the envelope of plain renormalization and factorization scale uncertainties.Comment: 23 pages, 7 figure

NNLOPS simulation of Higgs boson production

We detail a simulation of Higgs boson production via gluon fusion, accurate at next-to-next-to-leading order in the strong coupling, including matching to a parton shower, yielding a fully exclusive, hadron-level description of the final-state. The approach relies on the POWHEG method for merging the NLO Higgs plus jet cross-section with the parton shower, and on the MINLO method to simultaneously achieve NLO accuracy for inclusive Higgs boson production. The NNLO accuracy is reached by a reweighting procedure making use of the HNNLO program.Comment: 25 pages, 10 figures. Very minor clarifications in the text for v

Merging WW and WW+jet with MINLO

We present a simulation program for the production of a pair of W bosons in association with a jet, that can be used in conjunction with general-purpose shower Monte Carlo generators, according to the POWHEG method. We have further adapted and implemented the MINLO' method on top of the NLO calculation underlying our WW+jet generator. Thus, the resulting simulation achieves NLO accuracy not only for inclusive distributions in WW+jet production but also WW production, i.e. when the associated jet is not resolved, without the introduction of any unphysical merging scale. This work represents the first extension of the MINLO' method, in its original form, to the case of a genuine underlying 2->2 process, with non-trivial virtual corrections.Comment: 22 pages, 9 figure

Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation

The goal of the current work was to profile positive (mTORC1 activation, autocrine/paracrine growth factors) and negative [AMPK, unfolded protein response (UPR)] pathways that might regulate overload-induced mTORC1 (mTOR complex 1) activation with the hypothesis that a number of negative regulators of mTORC1 will be engaged during a supraphysiological model of hypertrophy. To achieve this, mTORC1- IRS-1/2 signaling, BiP/CHOP/IRE1, and AMPK activation were determined in rat plantaris muscle following synergist ablation (SA). SA resulted in significant increases in muscle mass of 4% per day throughout the 21 days of the experiment. The expression of the insulin-like growth factors (IGF) were high throughout the 21st day of overload. However, IGF signaling was limited, since IRS-1 and -2 were undetectable in the overloaded muscle from day 3 to day 9. The decreases in IRS-1/2 protein were paralleled by increases in GRB10 Ser501/503 and S6K1 Thr389 phosphorylation, two mTORC1 targets that can destabilize IRS proteins. PKB Ser473 phosphorylation was higher from 3– 6 days, and this was associated with increased TSC2 Thr939 phosphorylation. The phosphorylation of TSC2 Thr1345 (an AMPK site) was also elevated, whereas phosphorylation at the other PKB site, Thr1462, was unchanged at 6 days. In agreement with the phosphorylation of Thr1345, SA led to activation of AMPK1 during the initial growth phase, lasting the first 9 days before returning to baseline by day 12. The UPR markers CHOP and BiP were elevated over the first 12 days following ablation, whereas IRE1 levels decreased. These data suggest that during supraphysiological muscle loading at least three potential molecular brakes engage to downregulate mTORC1. m

Finite element model of an impact on a palmar pad from a snowboard wrist protector

Wrist injuries are the most common types of injury in snowboarding. Protectors can reduce injury risk by limiting wrist hyperextension and attenuating impact forces. There are a range of wrist protector concepts available, but it is unclear if any particular design is more effective. The aim of this study was to develop and validate a finite element model of an impact on the palmar pad from a protector. Pad material from a protector was characterised to obtain stress vs strain data, and determine whether it was rate dependent. Material data was implemented into a finite element model to predict impact behavior at 2.5 J. Four material models were investigated, with an Ogden model paired with a Prony series providing the best agreement to experimental data. Future work will build a model of a complete protector for predicting the protective levels of these products

Improving NLO-parton shower matched simulations with higher order matrix elements

In recent times the algorithms for the simulation of hadronic collisions have been subject to two substantial improvements: the inclusion, within parton showering, of exact higher order tree level matrix elements (MEPS) and, separately, next-to-leading order corrections (NLOPS). In this work we examine the key criteria to be met in merging the two approaches in such a way that the accuracy of both is preserved, in the framework of the POWHEG approach to NLOPS. We then ask to what extent these requirements may be fulfilled using existing simulations, without modifications. The result of this study is a pragmatic proposal for merging MEPS and NLOPS events to yield much improved MENLOPS event samples. We apply this method to W boson and top quark pair production. In both cases results for distributions within the remit of the NLO calculations exhibit no discernible changes with respect to the pure NLOPS prediction; conversely, those sensitive to the distribution of multiple hard jets assume, exactly, the form of the corresponding MEPS results.Comment: 38 pages, 17 figures. v2: added citations and brief discussion of related works, MENLOPS prescription localized in a subsection. v3: cited 4 more MEPS works in introduction