190 research outputs found
Expectations about Fertility and Field of Study among Adolescents: A Case of Self-selection?
In recent studies on the association between education and fertility, increased attention has been paid to the field of study. Women who studied in traditionally more “feminine” fields, like care, teaching, and health, were found to have their children earlier and to have more children than other women. A point of debate in this literature is on the causal direction of this relationship. Does the field of study change the attitudes towards family formation, or do young adults with stronger family-life attitudes self-select into educational fields that emphasize care, teaching, and health? Or do both field of study preferences and family-life attitudes arise before actual choices in these domains are made?We contribute to this debate by examining the relationship between fertility expectations and expected fields of study and occupation among 14-17 year-old adolescents. We use data collected in 2005 from 1500 Dutch adolescents and Structural Equation Modelling (SEM) to examine the associations between expected field of study and occupation and fertility expectations. Our results show that expectations concerning fertility and field of study are already interrelated during secondary education. Both female and male adolescents who expect to pursue studies in fields that focus on care and social interaction (like health care, teaching etc.) are less likely to expect to remain childless. This holds equally for girls and boys. In addition, girls who more strongly aspire to an occupation in which communication skills are important also expect to have more children. We did not find any relationship between expectations of pursuing a communicative field of study and occupation and expectations of earlier parenthood.In addition, among boys, we find that the greater their expectation of opting for an economics, a technical, or a communicative field of study, the less likely they were to expect to remain childless. Boys who expected to study in the economic field also expect to have their first child earlier, but boys expecting to pursue a technical course of studies expect to enter parenthood later. We also found that those who expect to pursue cultural studies are more likely to have a preference for no children, or if they do want children, to have them later in life.Overall, our findings suggest that the processes of elective affinity between the communicative fields of study and work on the one hand and fertility on the other hand are more or less comparable for boys and girls. With respect to the other domains, we find, apart from the gender differences in the relation between fields of study and childlessness, hardly or no gender differences in the expected timing of parenthood and the number of children. The genders do differ in their level of preference for communicative and economics-related fields of study and occupation, but if they do have the same preference, the association with fertility expectations is more or less similar
Ileal Mucosal and Fecal Pancreatitis Associated Protein Levels Reflect Severity of Salmonella Inflection in Rats
Background Microbial infections induce ileal pancreatitis-associated protein/regenerating gene III (PAP/RegIII) mRNA expression. Despite increasing interest, little is known about the PAP/RegIII protein. Therefore, ileal mucosal PAP/RegIII protein expression, localization, and fecal excretion were studied in rats upon Salmonella infection. Results Salmonella infection increased ileal mucosal PAP/RegIII protein levels in enterocytes located at the crypt-villus junction. Increased colonization and translocation of Salmonella was associated with higher ileal mucosal PAP/RegIII levels and secretion of this protein in feces. Conclusions PAP/RegIII protein is increased in enterocytes of the ileal mucosa during Salmonella infection and is associated with infection severity. PAP/RegIII is excreted in feces and might be used as a new and non-invasive infection marke
The relationship between sigmoidal intramucosal pH and intestinal arterial occlusion during aortic reconstructive surgery
Objectives:To investigate the effects of perioperative occlusion of intestinal arteries on clinical outcome and changes in sigmoidal intramuscular pH (pHi). To determine the value of sigmoidal pHi measurement in predicting ischaemic colitis after aortic reconstructive surgery.Design:Prospective, non-selective, open study.Materials:Forty patients undergoing elective aortic infrarenal surgery were monitored with pHi. Pre- and postoperative digital venous subtraction angiography was combined with operative data to evaluate perioperative occlusion of intestinal arteries.Results:All patients had a significant (p < 0.05) drop in pHi after aortic clamping which returned to baseline 2–4 h after declamping. None of the patients had clinical signs of ischaemic colitis postoperatively. All patients had angiographically proven, patent superior mesenteric arteries pre- and postoperatively. Patients were divided into three groups: patients with no changes in intestinal arteries (n = 13), patients with perioperative occlusion of the inferior mesenteric artery (n = 22) and patients with perioperative occlusion of the inferior mesenteric and one or both iliac arteries (n = 5); there were no significant differences in pHi values between the groups.Conclusions:Return of the sigmoidal pHi to baseline values within 6–12 h after declamping probably predicts a postoperative course without ischaemic colitis. Perioperative occlusion of the inferior mesenteric artery alone, or in combination with occlusion of one or both internal iliac arteries, does not cause ischaemic colitis in patients whose sigmoidal pHi rises after declamping
A biomechanical model of anther opening reveals the roles of dehydration and secondary thickening
Understanding the processes that underlie pollen release is a prime target for controlling fertility to enable selective breeding and the efficient production of hybrid crops. Pollen release requires anther opening, which involves changes in the biomechanical properties of the anther wall. In this research, we develop and use a mathematical model to understand how these biomechanical processes lead to anther opening
Adolescents' Expectations About the Timing of Family Life Events:Unraveling the Role of Value Transmission and Modeling
Intergenerational continuity in family behaviors partly results from socialization processes in the parental home. However, socialization is a multidimensional process. This article tests hypotheses about the relative importance of value transmission and modeling in explaining expectations of adolescence concerning the timing of leaving home, and entry into cohabitation, marriage, and parenthood. Structural equation modeling on multiactor data from over 1,000 parent–adolescent child couples in the Netherlands is used to test hypotheses. Results suggest that, in general, both value transmission and modeling are important predictors of adolescents’ expectations concerning the timing of major family events. Moreover, no differences between mothers and fathers and between boys and girls are observed in the strength of the intergenerational relationships studied
Mito-Nuclear Communication by Mitochondrial Metabolites and Its Regulation by B-Vitamins
Mitochondria are cellular organelles that control metabolic homeostasis and ATP generation, but also play an important role in other processes, like cell death decisions and immune signaling. Mitochondria produce a diverse array of metabolites that act in the mitochondria itself, but also function as signaling molecules to other parts of the cell. Communication of mitochondria with the nucleus by metabolites that are produced by the mitochondria provides the cells with a dynamic regulatory system that is able to respond to changing metabolic conditions. Dysregulation of the interplay between mitochondrial metabolites and the nucleus has been shown to play a role in disease etiology, such as cancer and type II diabetes. Multiple recent studies emphasize the crucial role of nutritional cofactors in regulating these metabolic networks. Since B-vitamins directly regulate mitochondrial metabolism, understanding the role of B-vitamins in mito-nuclear communication is relevant for therapeutic applications and optimal dietary lifestyle. In this review, we will highlight emerging concepts in mito-nuclear communication and will describe the role of B-vitamins in mitochondrial metabolite-mediated nuclear signaling
Языковое своеобразие стихотворения Зульфии "Пришла весна, спрашивает о тебе"
В жизни и творчестве узбекской поэтессы Зульфии Исраиловой особую роль играет весна. Она родилась в первый день весны. Каждую весну с момента гибели спутника жизни поэта Хамида Олимджана, любившего эту пору, Зульфия посвящала ему стихотворение. Всего их пятьдесят.
При цитировании документа, используйте ссылку http://essuir.sumdu.edu.ua/handle/123456789/3470
Interference of flavonoids with enzymatic assays for the determination of free fatty acid and triglyceride levels
Flavonoids are bioactive food compounds with potential lipid-lowering effects. Commercially available enzymatic assays are widely used to determine free fatty acid (FFA) and triglyceride (TG) levels both in vivo in plasma or serum and in vitro in cell culture medium or cell lysate. However, we have observed that various flavonoids interfere with peroxidases used in these enzymatic assays, resulting in incorrect lower FFA and TG levels than actually present. Furthermore, addition of isorhamnetin or the major metabolite of the flavonoid quercetin in human and rat plasma, quercetin-3-O-glucuronide, to murine serum also resulted in a significant reduction of the detected TG levels, while a trend was seen for FFA levels. It is concluded that when applying these assays, vigilance is needed and alternative analytical methods, directly assessing FFA or TG levels, should be used for studying the biological effects of flavonoids on FFA and TG levels
Inter-observer variability of visual analysis of “stress”-only adenosine first-pass myocardial perfusion imaging in relation to clinical experience and reading criteria
To assess the inter-observer agreement of adenosine “stress”-only visual analysis of perfusion MR images in relation to experience and reading criteria. 106 adenosine perfusion MR examinations out of 350, 46 consecutive positive examinations and 60 randomly selected negative examinations were visually analysed by three individual readers (two residents and a technician) with different levels of experience. Readings (blinded for any information) were compared with the reading of an expert radiologist. After a month the examinations were presented again (randomly) without knowledge regarding the first readings. This time readings were performed with the systematical use of reading criteria. Agreement with the expert reading was good for the most experienced resident (k = 0.88). Kappa was 0.48 for the least experienced, and 0.57 for the technician. After the second systematical reading inter-observer agreement increased to 0.9, 0.68 and 0.77 respectively. Overall kappa increased from 0.59 to 0.71. The use of reading criteria significantly improved the performance of the least experienced reader (P = 0.01). Visual analysis of adenosine “stress”-only first-pass perfusion MR images has moderate to very good agreement. Performance is experience related, but the systematic use of reading criteria significantly increased performance for the least experienced observer
Comparison of four mathematical models to analyze indicator-dilution curves in the coronary circulation
While several models have proven to result in accurate estimations when measuring cardiac output using indicator dilution, the mono-exponential model has primarily been chosen for deriving coronary blood/plasma volume. In this study, we compared four models to derive coronary plasma volume using indicator dilution; the mono-exponential, power-law, gamma-variate, and local density random walk (LDRW) model. In anesthetized goats (N = 14), we determined the distribution volume of high molecular weight (2,000 kDa) dextrans. A bolus injection (1.0 ml, 0.65 mg/ml) was given intracoronary and coronary venous blood samples were taken every 0.5–1.0 s; outflow curves were analyzed using the four aforementioned models. Measurements were done at baseline and during adenosine infusion. Absolute coronary plasma volume estimates varied by ~25% between models, while the relative volume increase during adenosine infusion was similar for all models. The gamma-variate, LDRW, and mono-exponential model resulted in volumes corresponding with literature, whereas the power-model seemed to overestimate the coronary plasma volume. The gamma-variate and LDRW model appear to be suitable alternative models to the mono-exponential model to analyze coronary indicator-dilution curves, particularly since these models are minimally influenced by outliers and do not depend on data of the descending slope of the curve only
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