Metatarsophalangeal joint pain in psoriatic arthritis: a cross-sectional study

Methods. Thirty-four consecutive patients with PsA (mean age 45.3 years, 65% female, mean disease duration 9.9 years) and 22 control participants (mean age 37.9 years, 64% female) underwent clinical and US examination to determine the presence of pain, swelling, synovitis, erosions, effusions and submetatarsal bursae at the MTP joints. Mean barefoot peak plantar pressures were determined at each MTP joint. Levels of pain, US-determined pathology and peak pressures were compared between groups. Binary logistic regression was used to identify demographic, clinical examination-derived, US-derived and plantar pressure predictors of pain at the MTP joints in the PsA group. Results. The presence of pain, deformity, synovitis, erosions (P < 0.001) and submetatarsal bursae and peak plantar pressure at MTP 3 (P < 0.05) were significantly higher in the PsA group. MTP joint pain in PsA was independently predicted by high BMI, female gender and the presence of joint subluxation, synovitis and erosion. Conclusion. These results suggest local inflammatory and structural factors, together with systemic factors (gender, BMI), are predominantly responsible for painful MTP joints in PsA, with no clear role for plantar pressure characteristics

Hydraulic Responses of Shrubs and Grasses to Fire Frequency and Drought in a Tallgrass Prairie Experiencing Bush Encroachment

The increase in abundance and density of woody plants in herbaceous ecosystems (i.e. bush encroachment) is occurring globally and is driven by reduced fire frequency, climate change, and the utilization of deeper, more reliable soil water by woody plants. Thus, a comprehensive understanding of the physiological processes through which woody and herbaceous plants use water will provide greater insight into the mechanisms of bush encroachment, as well as the trajectory of encroachment in a changing climate. Our objective was to assess how experimental changes in water availability and fire frequency impact belowground water-use traits in Cornus drummondii, the primary encroaching shrub within North American tallgrass prairies, and Andropogon gerardii, a dominant C4 grass. Shelters that reduced precipitation by 50% (drought) and 0% (control) were built over mature shrubs growing in sites that were burned at 1-year and 4-year frequencies. We assessed the water transport capability of shrubs and grasses growing in each treatment by measuring the maximum hydraulic conductance (Kmax) of entire root systems. We also assessed the vulnerability of shrub root segments to loss of hydraulic function by measuring the pressure at which 50% of the maximum hydraulic conductivity is lost (P50). Grass and shrub roots had opposite responses to drought and these patterns varied with fire treatment. Grasses growing in drought plots had lower root Kmax than control grasses. Conversely, root Kmax did not differ significantly between treatments in shrubs. However, drought shrub roots were less vulnerable to water stress than control roots (P50=-1.5 and -0.20 MPa, respectively). These results suggest that the ability of grass roots to use water declined with drought, while the ability of shrub roots to resist water stress increased with drought. Future work should investigate whether these drought responses are associated with altered root growth patterns

Is the Cygnus Loop two supernova remnants?

The Cygnus Loop is classified as a middle-aged supernova remnant (SNR) located below the Galactic equator (l=74, b=-8.6) and 770 pc away from us. Its large size and little confusion with Galactic emission makes it an ideal test ground for evolutionary and structural theories of SNRs. New radio continuum mapping of the Cygnus Loop at 2695 MHz with the Effelsberg 100-m telescope provides indications that the Cygnus Loop consists of two separate SNRs. Combining this result with data from the literature we argue that a secondary SNR exists in the south with a recently detected neutron star close to its center. Two interacting SNRs seem to be the best explanation to account for the Cygnus Loop observations at all wavelengths.Comment: 4 pages, 2 figures, Astron. Astrophys., accepte

The sea ice model component of HadGEM3-GC3.1

A new sea ice configuration, GSI8.1, is implemented in the Met Office global coupled configuration HadGEM3-GC3.1 which will be used for all CMIP6 (Coupled Model Intercomparison Project Phase 6) simulations. The inclusion of multi-layer thermodynamics has required a semi-implicit coupling scheme between atmosphere and sea ice to ensure the stability of the solver. Here we describe the sea ice model component and show that the Arctic thickness and extent compare well with observationally based data

Radiation of Neutron Stars Produced by Superfluid Core

We find that neutron star interior is transparent for collisionless electron sound, the same way as it is transparent for neutrinos. In the presence of magnetic field the electron sound is coupled with electromagnetic radiation and form the fast magnetosonic wave. We find that electron sound is generated by superfluid vortices in the stellar core. Thermally excited helical vortex waves produce fast magnetosonic waves in the stellar crust which propagate toward the surface and transform into outgoing electromagnetic radiation. The vortex radiation has the spectral index -0.45 and can explain nonthermal radiation of middle-aged pulsars observed in the infrared, optical and hard X-ray bands. The radiation is produced in the stellar interior which allows direct determination of the core temperature. Comparing the theory with available spectra observations we find that the core temperature of the Vela pulsar is T=8*10^8K, while the core temperature of PSR B0656+14 and Geminga exceeds 2*10^8K. This is the first measurement of the temperature of a neutron star core. The temperature estimate rules out equation of states incorporating Bose condensations of pions or kaons and quark matter in these objects. Based on the temperature estimate and cooling models we determine the critical temperature of triplet neutron superfluidity in the Vela core Tc=(7.5\pm 1.5)*10^9K which agrees well with recent data on behavior of nucleon interactions at high energies. Another finding is that in the middle aged neutron stars the vortex radiation, rather then thermal conductivity, is the main mechanism of heat transfer from the stellar core to the surface. Electron sound opens a perspective of direct spectroscopic study of superdense matter in the neutron star interiors.Comment: 43 pages, 7 figures, to appear in Astrophysical Journa

Rothamsted Conference RC No 5 : The art and science cultivation

RESP-51