Clinical encounter and the logic of relationality : Reconfiguring bodies and subjectivities in clinical relations

Acknowledgements I would like to thank all the patients and staff for their collaboration in the study and to acknowledge the other members of the team: James N’Dow and Sara MacLennan for their helpful guidance. I am grateful to Zoë Skea and Vikki Entwistle for the early discussions of the paper, to Natasha Mauthner and Lorna McKee for their insightful comments to various drafts, and to two anonymous reviewers for their thoughtful suggestions, which helped to clarify its argument. Funding The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research was supported by a grant from the Big Lottery Fund. The views expressed here are the author’s and do not necessarily reflect those of the funding bodies or any other organisation.Peer reviewedPostprin

Medical Imaging and the "Borderline Gaze of Touch and Hearing" : The Politics of Knowledge beyond "Sense Atomism"

I would like to thank the editors of this Special Section, Bettina Papenburg, Liv Hausken, Sigrid Schmitz and Natasha Myers, and the two anonymous reviewers for their careful reading of my work and helpful suggestions on how to clarify its arguments. I would also like to thank the participants of the Authors’ Workshop at 7th New Materialism Annual Conference “Performing Situated Knowledges: Space, Time, Vulnerability”, Warsaw, Poland, 21-23 September 2016, and the participants at “New Materialisms and Politics” Workshop at the University of Aberdeen, UK, 21-22 September 2017, for their comments and reactions to the earlier drafts of this article.Peer reviewedPublisher PD

Deep redshift topological lensing: strategies for the T^3 candidate

The 3-torus (T^3) FLRW model better fits the nearly zero large-scale auto-correlation of the WMAP CMB sky maps than the infinite flat model. The T^3 model's WMAP parameters imply approximately equal-redshift topological lensing at z \sim 6. We investigate observational strategies for rejecting the T^3 solution or providing candidate topologically lensed galaxy pairs. T^3 holonomies are applied to (i) existing z \sim 6 observations and (ii) simulated observations, creating multiply connected catalogues. Corresponding simply connected catalogues are generated. Each catalogue is analysed using a successive filter method and collecting matched quadruples. Quadruple statistics between the multiply and simply connected catalogues are compared. The expected rejection of the hypothesis, or detection of candidate topologically lensed galaxies, is possible at a significance of 5% for a pair of T^3 axis-centred northern and southern surveys if photometric redshift accuracy is \sigma(\zphot) < 0.01 for a pair of nearly complete 100 deg^2 surveys with a total of > 500 galaxies over 4.3 < z < 6.6, or for a pair of 196 deg^2 surveys with > 400 galaxies and \sigma(\zphot) < 0.02 over 4<z<7. Dropping the maximum time interval in a pair from \Delta t =1 Gyr/h to \Delta t =0.1 Gyr/h yields a requirement of \sigma(\zphot) < 0.005 or \sigma(\zphot) < 0.01, respectively. Millions of z \sim 6 galaxies will be observed over fields of these sizes during the coming decades, implying much stronger constraints. The question is not if the hypothesis will be rejected or confirmed, it is when.Comment: 13 pages, 9 figures, 5 tables, MNRAS, accepte

Identifying future study designs for mental health and social wellbeing associated with diets of a cohort living in eco-regions:findings from the INSUM Expert Workshop

Diets influence our mental health and social wellbeing (MHSW) in multiple ways. A rising community concept, Eco-Regions, has gained interest. The research project “Indicators for assessment of health effects of consumption of sustainable, organic school meals in Ecoregions” (INSUM) aims to develop future-oriented research approaches to measure the potential health effects of more sustainable and healthy diets. This first part of the project focuses on MHSW with the goal to identify suitable study designs and indicators. The methodology is based on a 2-day workshop with an interdisciplinary group of experts. This paper describes commonly applied research methods on the nexus between diet and MHSW as presented by the experts and summarises key points from the discussions. The results show that the dominating tool to investigate MSHW is questionnaires. Questionnaires vary largely depending on the research design, such as participants or distribution channels. Cohort studies addressing families and including in-depth interventional and/or experimental studies may be suitable for an Eco-Region investigation. Those MHSW studies can be conducted and combined with measurements of somatic health effects. We conclude that indicators should be seen as complementary rather than independent. Explorative research designs are required to investigate complex Eco-Regions

Unmet psychosocial needs in haematological cancer: A systematic review

The final publication is available at Springer via http://dx.doi.org/10.1007/s00520-014-2123-5A systematic review of key online databases and psycho-oncology journals was conducted to identify papers that formally assessed unmet psychosocial needs in adults with a diagnosis of haematological cancer

ATPase activity in macula densa cells of the rabbit kidney

Na-K- and Mg-activated ATPase activities were determined in maculae densae and glomeruli dissected from both superficial and juxtamedullary nephrons of normal rabbits, using an ultramicro method including a cycling reaction. Activities were expressed as P i generated per macula densa or per glomerulus and normalized for tissue volume. Results indicate that the mean volume of superficial and juxtamedullary macula densa samples was not statistically different, while glomeruli from deep nephrons had sample volumes that were 29% larger than those from superficial nephrons ( P <0.001). Correcting for volume both superficial and juxtamedullary macula densa samples had an Na-K-ATPase activity of 0.37±0.21 fmol · h −1 · (μm 3 ) −1 . Mg-ATPase activity in both pools was also similar [0.41±0.07 and 0.52±0.1 fmol · h −1 · (μm 3 ) −1 ]. Na-K-ATPase activity in macula densa cells is estimated to be about 1/40th the activity of surrounding cortical thick ascending limb cells. Total glomerular ATPase per unit volume was significantly higher in glomeruli from superficial than from deep nephrons [0.41±0.04 vs. 0.28±0.04 fmol · h −1 · (μm 3 ) −1 P <0.05]. There was no statistically significant activity of Na-K-ATPase in either superficial or deep glomeruli. These results suggest that in contrast to previous reports, the macula densa contains Na-K-ATPase, but at a low level relative to surrounding tubular cells. Further, in normal rabbits, this activity is invariant in superficial and juxtamedullary samples.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47454/1/424_2004_Article_BF00580725.pd

Antibiotic resistance determinants in the interplay between food and gut microbiota

A complex and heterogeneous microflora performs sugar and lactic acid fermentations in food products. Depending on the fermentable food matrix (dairy, meat, vegetable etc.) as well as on the species composition of the microbiota, specific combinations of molecules are produced that confer unique flavor, texture, and taste to each product. Bacterial populations within such “fermented food microbiota” are often of environmental origin, they persist alive in foods ready for consumption, eventually reaching the gastro-intestinal tract where they can interact with the resident gut microbiota of the host. Although this interaction is mostly of transient nature, it can greatly contribute to human health, as several species within the food microbiota also display probiotic properties. Such an interplay between food and gut microbiota underlines the importance of the microbiological quality of fermented foods, as the crowded environment of the gut is also an ideal site for genetic exchanges among bacteria. Selection and spreading of antibiotic resistance genes in foodborne bacteria has gained increasing interest in the past decade, especially in light of the potential transferability of antibiotic resistance determinants to opportunistic pathogens, natural inhabitants of the human gut but capable of acquiring virulence in immunocompromised individuals. This review aims at describing major findings and future prospects in the field, especially after the use of antibiotics as growth promoters was totally banned in Europe, with special emphasis on the application of genomic technologies to improve quality and safety of fermented foods