7,116 research outputs found
N=2 Supersymmetric Model with Dirac-Kahler Fermions from Generalized Gauge Theory in Two Dimensions
We investigate the generalized gauge theory which has been proposed
previously and show that in two dimensions the instanton gauge fixing of the
generalized topological Yang-Mills action leads to a twisted N=2 supersymmetric
action. We have found that the R-symmetry of N=2 supersymmetry can be
identified with the flavour symmetry of Dirac-Kahler fermion formulation. Thus
the procedure of twist allows topological ghost fields to be interpreted as the
Dirac-Kahler matter fermions.Comment: 22 pages, LaTe
Nuclear Physics from lattice QCD at strong coupling
We study numerically the strong coupling limit of lattice QCD with one flavor
of massless staggered quarks. We determine the complete phase diagram as a
function of temperature and chemical potential, including a tricritical point.
We clarify the nature of the low temperature dense phase, which is strongly
bound nuclear matter. This strong binding is explained by the nuclear
potential, which we measure. Finally, we determine, from this first-principle
limiting case of QCD, the masses of atomic nuclei up to A=12 "carbon".Comment: 4 pages, 5 figures; v2: references added, minor changes, published
versio
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Metabolic syndrome does not affect sustained virologic response of direct-acting antivirals while hepatitis C clearance improves hemoglobin A1c.
AimTo determine whether successful treatment with directacting antivirals (DAA) is associated with improvements in hemoglobin A1c (HbA1c) and if type 2 diabetes mellitus (T2DM) or metabolic syndrome affects sustained virologic response (SVR).MethodsWe performed a retrospective analysis of all hepatitis C virus (HCV) patients at the VA Greater Los Angeles Healthcare System treated with varying DAA therapy between 2014-2016. Separate multivariable logistic regression was performed to determine predictors of HbA1c decrease ≥ 0.5 after DAA treatment and predictors of SVR 12-wk post treatment (SVR12).ResultsA total of 1068 patients were treated with DAA therapy between 2014-2016. The presence of T2DM or metabolic syndrome did not adversely affect SVR12. 106 patients had both HCV and T2DM. Within that cohort, patients who achieved SVR12 had lower mean HbA1c pre treatment (7.35 vs 8.60, P = 0.02), and lower mean HbA1c post-treatment compared to non-responders (6.55 vs 8.61, P = 0.01). The mean reduction in HbA1c after treatment was greater for those who achieved SVR12 than for non-responders (0.79 vs 0.01, P = 0.03). In adjusted models, patients that achieved SVR12 were more likely to have a HbA1c decrease of ≥ 0.5 than those that did not achieve SVR12 (adjusted OR = 7.24, 95%CI: 1.22-42.94).ConclusionIn HCV patients with T2DM, successful treatment with DAA was associated with a significant reduction in HbA1c suggesting that DAA may have a role in improving insulin sensitivity. Furthermore, the presence of T2DM or metabolic syndrome does not adversely affect SVR12 rates in patients treated with DAA
Note on Dirac--K\"ahler massless fields
We obtain the canonical and symmetrical Belinfante energy-momentum tensors of
Dirac--K\"{a}hler's fields. It is shown that the traces of the energy-momentum
tensors are not equal to zero. We find the canonical and Belinfante dilatation
currents which are not conserved, but a new conserved dilatation current is
obtained. It is pointed out that the conformal symmetry is broken. The
canonical quantization is performed and the propagator of the massless fields
in the first-order formalism is found.Comment: 16 pages, minor corrections in the text, published versio
The 30/20 GHz flight experiment system, phase 2. Volume 3: Experiment system requirement document
An approach to the requirements document to be used to procure the system by NASA is presented. The basic approach is similar to the requirements document used in the commercial communication satellite. Enough detail requirements are given to define the system without tight constraints
The 30/20 GHz flight experiment system, phase 2. Volume 2: Experiment system description
A detailed technical description of the 30/20 GHz flight experiment system is presented. The overall communication system is described with performance analyses, communication operations, and experiment plans. Hardware descriptions of the payload are given with the tradeoff studies that led to the final design. The spacecraft bus which carries the payload is discussed and its interface with the launch vehicle system is described. Finally, the hardwares and the operations of the terrestrial segment are presented
The 30/20 GHz flight experiment system, phase 2. Volume 1: Executive summary
Summary information on the final communication system design, communication payload, space vehicle, and development plan for the 30/20 GHz flight experiment will be installed on the LEASAT spacecraft which will be placed into orbit from the space shuttle cargo bay. The communication concept has two parts: a truck service and a customer premise service (CPS). The trucking system serves four spot beams which are interconnected in a satellite switched time division multiple access mode by an IF switch matrix. The CPS covers two large areas of the eastern United States with a pair of scanning beams
Microscopic analysis of the microscopic reversibility in quantum systems
We investigate the robustness of the microscopic reversibility in open
quantum systems which is discussed by Monnai [arXiv:1106.1982 (2011)]. We
derive an exact relation between the forward transition probability and the
reversed transition probability in the case of a general measurement basis. We
show that the microscopic reversibility acquires some corrections in general
and discuss the physical meaning of the corrections. Under certain processes,
some of the correction terms vanish and we numerically confirmed that the
remaining correction term becomes negligible; the microscopic reversibility
almost holds even when the local system cannot be regarded as macroscopic.Comment: 12 pages, 10 figure
Inner products of resonance solutions in 1-D quantum barriers
The properties of a prescription for the inner products of the resonance
(Gamow states), scattering (Dirac kets), and bound states for 1-dimensional
quantum barriers are worked out. The divergent asypmtotic behaviour of the
Gamow states is regularized using a Gaussian convergence factor first
introduced by Zel'dovich. With this prescription, most of these states (with
discrete complex energies) are found to be orthogonal to each other, to the
bound states, and to the Dirac kets, except when they are neighbors, in which
case the inner product is divergent. Therefore, as it happens for the continuum
scattering states, the norm of the resonant ones remains non-calculable. Thus,
they exhibit properties half way between the (continuum real) Dirac-delta
orthogonality and the (discrete real) Kronecker-delta orthogonality of the
bound states.Comment: 13 pages, 2 figure
Superoxide dismutase analog (Tempol: 4-hydroxy-2, 2, 6, 6-tetramethylpiperidine 1-oxyl) treatment restores erectile function in diabetes-induced impotence.
We hypothesized that the administration of the superoxide dismutase (SOD) mimetic Tempol (4-hydroxy-2, 2, 6, 6-tetramethylpiperidine 1-oxyl) may reverse diabetes-induced erectile dysfunction. To test this hypothesis, reactive oxygen species-related genes (SOD1, SOD2, GP x 1, CAT, NOS2, NOS3) were tested, erectile functional studies and immunohistochemical analysis were carried out in diabetic rats treated with or without Tempol. Thirty Sprague-Dawley (3-4 months old) rats were divided into three groups (n=10 each), 20 with diabetes (diabetic control and Tempol treatment) and 10 healthy controls. At 12 weeks after the induction of diabetes by streptozotocin and Tempol treatment, all groups underwent in vivo cavernous nerve stimulation. Rat crura were harvested and the expression of antioxidative defense enzymes were examined by semi-quantitative reverse transcriptase PCR (RT-PCR). To confirm the RT-PCR results, we carried out immunohistochemistry (IHC) for catalase (CAT) and iNOS (NOS2). Nitration of tyrosine groups in proteins was also examined by IHC. Mean intracavernous pressure in the diabetic group was significantly lower than in the healthy controls (P <0.001) and was reversed by Tempol treatment (P <0.0108). NOS2 protein expression was significantly increased in diabetic animals compared with healthy controls and Tempol restored NOS2 protein level. Nitrotyrosine was also higher in diabetic animals and although Tempol treatment decreased its formation, it remained higher than that found in healthy controls. This study suggests that Tempol treatment increased erectile function through modulating oxidative stress-related genes in diabetic rats. This is the first report about the relationship between diabetes-induced erectile dysfunction and oxidative stress, and antioxidative therapy using the superoxide dismutase mimetic, Tempol, to restore erectile function
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