XMM-Newton observation of the interacting galaxies NGC1512 and NGC1510

The galaxy NGC1512 is interacting with the smaller galaxy NGC1510 and shows a peculiar morphology, characterised by two extended arms immersed in an HI disc whose size is about four times larger than the optical diameter of NGC1512. For the first time we performed a deep X-ray observation of the galaxies NGC1512 and NGC1510 with XMM-Newton to gain information on the population of X-ray sources and diffuse emission in a system of interacting galaxies. We identified and classified the sources detected in the XMM-Newton field of view by means of spectral analysis, hardness-ratios calculated with a Bayesian method, X-ray variability, and cross-correlations with catalogues in optical, infrared, and radio wavelengths. We also made use of archival Swift (X-ray) and Australia Telescope Compact Array (radio) data to better constrain the nature of the sources detected with XMM-Newton. We detected 106 sources in the energy range of 0.2-12 keV, out of which 15 are located within the D_25 regions of NGC1512 and NGC1510 and at least six sources coincide with the extended arms. We identified and classified six background objects and six foreground stars. We discussed the nature of a source within the D_25 ellipse of NGC1512, whose properties indicate a quasi-stellar object or an intermediate ultra-luminous X-ray source. Taking into account the contribution of low-mass X-ray binaries and active galactic nuclei, the number of high-mass X-ray binaries detected within the D_25 region of NGC1512 is consistent with the star formation rate obtained in previous works based on radio, infrared optical, and UV wavelengths. We detected diffuse X-ray emission from the interior region of NGC1512 with a plasma temperature of kT=0.68(0.31-0.87) keV and a 0.3-10 keV X-ray luminosity of 1.3E38 erg/s, after correcting for unresolved discrete sources.Comment: Accepted for publication in Astronomy and Astrophysics. 20 pages. Appendix B will be published electronically onl

You can hide but you have to run: direct detection with vector mediators

We study direct detection in simplified models of Dark Matter (DM) in which interactions with Standard Model (SM) fermions are mediated by a heavy vector boson. We consider fully general, gauge-invariant couplings between the SM, the mediator and both scalar and fermion DM. We account for the evolution of the couplings between the energy scale of the mediator mass and the nuclear energy scale. This running arises from virtual effects of SM particles and its inclusion is not optional. We compare bounds on the mediator mass from direct detection experiments with and without accounting for the running. In some cases the inclusion of these effects changes the bounds by several orders of magnitude, as a consequence of operator mixing which generates new interactions at low energy. We also highlight the importance of these effects when translating LHC limits on the mediator mass into bounds on the direct detection cross section. For an axial-vector mediator, the running can alter the derived bounds on the spin-dependent DM-nucleon cross section by a factor of two or more. Finally, we provide tools to facilitate the inclusion of these effects in future studies: general approximate expressions for the low energy couplings and a public code runDM to evolve the couplings between arbitrary energy scales

Translocation of proteins homologous to human neutrophil p47phox and p67phox to the cell membrane in activated hemocytes of Galleria mellonella

Activation of the superoxide forming respiratory burst oxidase of human neutrophils, crucial in host defence, requires the cytosolic proteins p47phox and p67phox which translocate to the plasma membrane upon cell stimulation and activate flavocytochrome b558, the redox centre of this enzyme system. We have previously demonstrated the presence of proteins (67 and 47 kDa) in hemocytes of the insect Galleria mellonella homologous to proteins of the superoxide-forming NADPH oxidase complex of neutrophils. The work presented here illustrates for the first time translocation of homologous hemocyte proteins, 67 and 47 kDa from the cytosol to the plasma membrane upon phorbol 12-myristate 13 acetate (PMA)activation. In hemocytes, gliotoxin (GT), the fungal secondary metabolite significantly suppressed PMA-induced superoxide generation in a concentration dependent manner and reduced translocation to basel nonstimulated levels. Primarily these results correlate translocation of hemocyte 47 and 67 kDa proteins with PMA induced oxidase activity. Collectively results presented here, demonstrate further cellular and functional similarities between phagocytes of insects and mammals and further justify the use of insects in place of mammals for modelling the innate immune response to microbial pathogens

Every partridge counts, successful techniques used in the captive conservation breeding programme for wild grey partridge in Ireland

Between 1998 and 2001 the last remaining wild grey partridge (Perdix perdix) population in Ireland faced imminent extinction with an estimated spring population of 4–6 pairs, and an autumn population of 22–24 birds. A captive breeding programme began in 2002 with two pairs of grey partridge. In the most successful year in 2010, 39 pairs produced a total of 510 chicks. Average chick survival rate was 65.13%. At 88.9 the highest chick survival rate was achieved in 2011. Chick survival of parent–reared birds in captivity is defined by the number of juveniles surviving at age six weeks: similar to estimations used for wild populations of grey partridge. Family coveys were released in late summer to early autumn. In most instances the entire family cohort was released as one unit. However, in coveys of twenty or above, an average of five parent–reared poults were held back as breeding stock for the following year. In early spring of the following year, birds held back were paired with single males or females trapped from the wild. The techniques we used were traditional and labour intensive but highly effective. We recommend that other grey partridge recovery projects should consider captive breeding using the methods employed in this programme to compliment other game management methods used

Constraining ^(26)Al+p resonances using ^(26)Al(^3He,d)^(27)Si

The ^(26)Al(^3He,d)^(27)Si reaction was measured from 0°≤θ_(c.m.)≤35° at E(^3He)=20 MeV using a quadrupole-dipole-dipole-dipole magnetic spectrometer. States in ^(27)Si were observed above the background at 7652 and 7741 keV and upper limits were set for the state at 7592 keV. Implications for the ^(26)Al(p,γ)^(27)Si stellar reaction rate are discussed

Octupolar invariants for compact binaries on quasicircular orbits

We extend the gravitational self-force methodology to identify and compute new O(μ) tidal invariants for a compact body of mass μ on a quasicircular orbit about a black hole of mass Mμ. In the octupolar sector we find seven new degrees of freedom, made up of 3+3 conservative/dissipative 'electric' invariants and 3+1 'magnetic' invariants, satisfying 1+1 and 1+0 trace conditions. We express the new invariants for equatorial circular orbits on Kerr spacetime in terms of the regularized metric perturbation and its derivatives; and we evaluate the expressions in the Schwarzschild case. We employ both Lorenz gauge and Regge-Wheeler gauge numerical codes, and the functional series method of Mano, Suzuki and Takasugi. We present (i) highly-accurate numerical data and (ii) high-order analytical post-Newtonian expansions. We demonstrate consistency between numerical and analytical results, and prior work. We explore the application of these invariants in effective one-body models and binary black hole initial-data formulations

Complementarity of direct detection experiments in search of light Dark Matter

Dark Matter experiments searching for Weakly interacting massive particles (WIMPs) primarily use nuclear recoils (NRs) in their attempt to detect WIMPs. Migdal-induced electronic recoils (ERs) provide additional sensitivity to light Dark Matter with $\mathcal{O}(\text{GeV}/c^2)$ masses. In this work, we use Bayesian inference to find the parameter space where future detectors like XENONnT and SuperCDMS SNOLAB will be able to detect WIMP Dark Matter through NRs, Migdal-induced ERs or a combination thereof. We identify regions where each detector is best at constraining the Dark Matter mass and spin independent cross-section and infer where two or more detection configurations are complementary to constraining these Dark Matter parameters through a combined analysis.Comment: 19 pages, 7 figure

Low-lying continuum structures in B8 and Li8 in a microscopic model

We search for low-lying resonances in the B8 and Li8 nuclei using a microscopic cluster model and a variational scattering method, which is analytically continued to complex energies. After fine-tuning the nucleon-nucleon interaction to get the known 1+ state of B8 at the right energy, we reproduce the known spectra of the studied nuclei. In addition, our model predicts a 1+ state at 1.3 MeV in B8, relative to the Be7+p threshold, whose corresponding pair is situated right at the Li7+n threshold in Li8. Lacking any experimental evidence for the existence of such states, it is presently uncertain whether these structures really exist or they are spurious resonances in our model. We demonstrate that the predicted state in B8, if it exists, would have important consequences for the understanding of the astrophysically important Be7(p,gamma)B8 reaction.Comment: 6 pages with 1 figure. The postscript file and more information are available at http://nova.elte.hu/~csot

Identification and characterization of an imidazolium by-product formed during the synthesis of 4-methylmethcathinone (mephedrone)

4-Methylmethcathinone (2-methylamino-1-(4-methylphenyl)propan-1-one, mephedrone) is a psychoactive substance that has been associated with recreational use worldwide. Analytical data related to mephedrone are abundantly available but the characterization of by-products obtained during organic synthesis remains to be explored. This study presents the identification of a 1,2,3,5-tetramethyl-4-(4-methylphenyl)-1H-imidazol-3-ium salt (TMMPI), which was formed during the synthesis of mephedrone. When diethyl ether was added to the crude reaction product, solid material precipitated from the solution. Analytical characterization of TMMPI employed a range of analytical techniques including chromatographic analysis in combination with various mass spectrometric detection methods, nuclear magnetic resonance spectroscopy, and crystal structure analysis. Additional confirmation was obtained from organic synthesis of the imidazolium by-product. When TMMPI was subjected to analysis by gas chromatography-mass spectrometry (GC-MS), isomerization and degradation into two distinct compounds were observed, which pointed towards thermal instability under GC conditions. A liquid chromatography-mass spectrometry (LC-MS) based investigation into a micro-scale synthesis of mephedrone and three additional analogues revealed that the corresponding TMMPI analogue was formed. Interestingly, storage of mephedrone freebase in a number of organic solvents also gave rise to TMMPI and it appeared that its formation during storage was significantly reduced in the absence of air. The present study aimed to support clandestine forensic investigations by employing analytical strategies that are applicable to manufacturing sites. The imidazolium salts will most likely be found amongst the waste products of any clandestine lab site under investigation rather than with the desired product