29,148 research outputs found
Preliminary study of inphase gusts and moment force wind loads over the first 150 meters at KSC, Florida
A mathematical/statistical analysis of inphase gusts and wind velocity moment forces over the first 150 m at the Kennedy Space Center (KSC) is presented. The wind velocity profile data were acquired at the KSC 150 m ground wind tower. The results show that planetary boundary layer (PBL) winds can sustain near peak speeds for periods up to 60 sec and longer. This is proven from calculating the autocorrelation functions of moment forces for several 10 min cases of wind profile data. The results show that lower atmospheric planetary boundary layer winds have periodic variations for long periods of time. This flow characteristic is valuable as aerospace vehicle engineering and design criteria where wind loading must be determined
Stable Direct Adaptive Control of Linear Infinite-dimensional Systems Using a Command Generator Tracker Approach
A command generator tracker approach to model following contol of linear distributed parameter systems (DPS) whose dynamics are described on infinite dimensional Hilbert spaces is presented. This method generates finite dimensional controllers capable of exponentially stable tracking of the reference trajectories when certain ideal trajectories are known to exist for the open loop DPS; we present conditions for the existence of these ideal trajectories. An adaptive version of this type of controller is also presented and shown to achieve (in some cases, asymptotically) stable finite dimensional control of the infinite dimensional DPS
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T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele.
Limited regions of amino acid sequence similarity frequently occur between microbial antigens and host proteins. It has been widely anticipated that during infection such sequence similarities could induce cross-reactive T cell responses, thereby initiating T cell-mediated autoimmune disease. However, the nature of major histocompatibility complex (MHC)-restricted antigen presentation confers a number of constraints that should make this type of T cell cross-reactivity a rare, MHC allele-dependent event. We tested this prediction using two insulin-dependent diabetes mellitus (IDDM)-associated antigens, coxsackievirus P2-C (Cox P2-C) protein and glutamate decarboxylase (GAD65), which share a prototypic sequence similarity of six consecutive amino acids within otherwise unrelated proteins. We surveyed a panel of 10 murine MHC class II alleles that encompass the spectrum of standard alleles for the ability to cross-reactively present Cox P2-C and GAD65. Out of the 10 restriction elements tested, the sequence similarity regions were both dominant determinants and were cross-reactively displayed after the natural processing of whole antigens, only in the context of I-Anod. These data show that cross-reactive T cell recognition of sequence similarity regions in unrelated proteins is confined to certain MHC alleles, which may explain MHC association with autoimmune disease. It is striking that these two diabetes-associated antigens were cross-reactively recognized only in the context of a diabetes susceptibility allele. Since the human and the murine class II alleles associated with IDDM share conserved features, cross-reactive T cell recognition of GAD65 and Cox P2-C may contribute to the pathogenesis of human IDDM and account for the epidemiological association of coxsackievirus with IDDM
The Production of HI in Photodissociation Regions and A Comparison with CO(1-0) Emission
The gas at the surfaces of molecular clouds in galaxies is heated and
dissociated by photons from young stars both near and far. HI resulting from
the dissociation of molecular hydrogen H2 emits hyperfine line emission at 21
cm, and warmed CO emits dipole rotational lines such as the 2.6 mm line of
CO(1-0). We use previously developed models for photodissociation regions
(PDRs) to compute the intensities of these HI and CO(1-0) lines as a function
of the total volume density n in the cloud and the far ultraviolet flux G0
incident upon it and present the results in units familiar to observers. The
intensities of these two lines behave differently with changing physical
conditions in the PDR, and, taken together, the two lines can provide a
ground-based radio astronomy diagnostic for determining n and G0 separately in
distant molecular clouds. This diagnostic is particularly useful in the range
Gzero <~ 100, 10 cm^{-3} <~ n <~ 10^5 cm^{-3}, which applies to a large
fraction of the volume of the interstellar medium in galaxies. If the molecular
cloud is located near discrete sources of far-UV (FUV) emission, the
PDR-generated HI and CO(1-0) emission on the cloud surface can be more easily
identified, appearing as layered ``blankets'' or ``blisters'' on the side of
the cloud nearest to the FUV source. As an illustration, we consider the
Galactic object G216 -2.5, i.e. ``Maddalena's Cloud'', which has been
previously identified as a large PDR in the Galaxy. We determine that this
cloud has n ~ 200 cm^{-3}, G0 ~ 0.8, consistent with other data.Comment: 13 Pages, 3 Figures. Accepted for publication in the Astrophysical
Journa
Cyclic structural analyses of anisotropic turbine blades for reusable space propulsion systems
Turbine blades for reusable space propulsion systems are subject to severe thermomechanical loading cycles that result in large inelastic strains and very short lives. These components require the use of anisotropic high-temperature alloys to meet the safety and durability requirements of such systems. To assess the effects on blade life of material anisotropy, cyclic structural analyses are being performed for the first stage high-pressure fuel turbopump blade of the space shuttle main engine. The blade alloy is directionally solidified MAR-M 246 alloy. The analyses are based on a typical test stand engine cycle. Stress-strain histories at the airfoil critical location are computed using the MARC nonlinear finite-element computer code. The MARC solutions are compared to cyclic response predictions from a simplified structural analysis procedure developed at the NASA Lewis Research Center
Simplified cyclic structural analyses of SSME turbine blades
Anisotropic high-temperature alloys are used to meet the safety and durability requirements of turbine blades for high-pressure turbopumps in reusable space propulsion systems. The applicability to anisotropic components of a simplified inelastic structural analysis procedure developed at the NASA Lewis Research Center is assessed. The procedure uses as input the history of the total strain at the critical crack initiation location computed from elastic finite-element analyses. Cyclic heat transfer and structural analyses are performed for the first stage high-pressure fuel turbopump blade of the space shuttle main engine. The blade alloy is directionally solidified MAR-M 246 (nickel base). The analyses are based on a typical test stand engine cycle. Stress-strain histories for the airfoil critical location are computed using both the MARC nonlinear finite-element computer code and the simplified procedure. Additional cases are analyzed in which the material yield strength is arbitrarily reduced to increase the plastic strains and, therefore, the severity of the problem. Good agreement is shown between the predicted stress-strain solutions from the two methods. The simplified analysis uses about 0.02 percent (5 percent with the required elastic finite-element analyses) of the CPU time used by the nonlinear finite element analysis
Cyclic stress analysis of an air-cooled turbine vane
The effects of gas pressure level, coolant temperature, and coolant flow rate on the stress-strain history and life of an air-cooled vane were analyzed using measured and calculated transient metal temperatures and a turbine blade stress analysis program. Predicted failure locations were compared to results from cyclic tests in a static cascade and engine. The results indicate that a high gas pressure was detrimental, a high coolant flow rate somewhat beneficial, and a low coolant temperature the most beneficial to vane life
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