4 research outputs found

    Poronienie i ciąża obumarła w aspekcie prawa – udział położnej w opiece nad pacjentką w sytuacji utraty ciąży = Miscarriage and pregnancy degenerated in terms of law - part midwife in the care of the patient in case of pregnancy loss

    Get PDF
    Stadnicka Sabina Katarzyna, Bień Agnieszka, Gdańska Paulina, Piechowska Joanna. Poronienie i ciąża obumarła w aspekcie prawa – udział położnej w opiece nad pacjentką w sytuacji utraty ciąży = Miscarriage and pregnancy degenerated in terms of law - part midwife in the care of the patient in case of pregnancy loss. Journal of Education, Health and Sport. 2016;6(9):379-390. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.62008 http://ojs.ukw.edu.pl/index.php/johs/article/view/3841 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015). 755 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author (s) 2016; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 05.08.2016. Revised 25.08.2016. Accepted: 06.09.2016. Poronienie i ciąża obumarła w aspekcie prawa – udział położnej w opiece nad pacjentką w sytuacji utraty ciąży Miscarriage and pregnancy degenerated in terms of law - part midwife in the care of the patient in case of pregnancy loss Sabina Katarzyna Stadnicka, mgr położnictwa, doktorantka, Katedra i Zakład Pielęgniarstwa Pediatrycznego, Wydział Nauk o Zdrowiu Uniwersytetu Medycznego w Lublinie Agnieszka Bień, dr n. med., adiunkt, Zakład Podstaw Położnictwa, Wydział Nauk o Zdrowiu Uniwersytetu Medycznego w Lublinie Paulina Gdańska, mgr psychologii, I Katedra i Klinika Położnictwa i Ginekologii Warszawskiego Uniwersytetu Medycznego Joanna Piechowska, mgr położnictwa, doktorantka, Zakład Podstaw Położnictwa, Wydział Nauk o Zdrowiu Uniwersytetu Medycznego w Lublinie Streszczenie Niekorzystne zakończenie ciąży ma charakter niezwykle złożony i delikatny. Utrata ciąży na skutek poronienia jest wydarzeniem biomedycznym wywierającym ogromny wpływ na funkcjonowanie psychiczne. Nowe Rozporządzenie Ministra Zdrowia z dnia 1 grudnia 2015r. wprowadza dokładnie określone standardy postępowań okołoporodowych w opiece nad pacjentkami w sytuacji niepowodzeń położniczych. Celem publikacji jest pokazanie istotności wprowadzenia standardów. Odpowiedni przekaz niepomyślnych wiadomości, poprawna komunikacja a także udzielenie wsparcia może załagodzić psychologiczne skutki niepomyślnej sytuacji. Słowa kluczowe: ciąża, poronienie, strata, przepisy prawa, zdrowie psychiczne Abstract Unfavorable termination of pregnancy is a very complex and delicate. Pregnancy loss due to miscarriage is an event biomedical exerting a huge influence on the functioning of mental health. The new Minister of Health of 1 December 2015. introduces precisely defined standards proceedings perinatal care for female patients in an obstetric failures. The aim of the publication is to show the significance of the introduction of standards. The corresponding message bad news, the correct communication and assistance can alleviate the psychological effects of unfavorable situation. Key words: pregnancy, miscarriage, loss, law, mental healt

    Novel Azocoumarin Derivatives—Synthesis and Characterization

    No full text
    The paper presents synthesis and characterization of nine new thiazolyl-(phenyldiazenyl)-2H-chromen-2-one dyes. The impact of substituent structure in thiazole ring in the synthesized azocoumarin derivatives on electrochemical properties, photoisomerization process and photovoltaic response was examined. The dyes were electrochemically active and undergo reduction and oxidation processes. They showed low electrochemically estimated energy band gap in the range of 1.71–2.13 eV. Photoisomerization process of the synthesized molecules was studied in various solvents such as ethanol, chloroform and N,N-dimethylformamide (DMF) upon the UV illumination. It was found that novel azodyes showed reversible trans-cis-trans isomerization and exhibited long thermal back to the trans form, that was even 7 days in DMF. Selected azocoumarin were molecularly dispersed in polystyrene for preparation of guest-host azopolymer systems to study the cis-trans thermal isomerization of obtained dyes in solid state. The photovoltaic activity of the azochromophores was tested in bulk-heterojunction solar cells. They acting as weak donors in device with structure ITO/PEDOT:PSS/dye:PC70BM/Al. No photovoltaic response of cells with azocoumarin derivatives bearing 4-fluorobenzene, 3,4-dichlorobenzene, or 4-(1-adamantyl) unit was found. Additionally, dye which showed the best activity was examined in three-component solar cells ITO/PEDOT:PSS/PTB7:PC70BM:dye/PFN/Al

    Tropinone-Derived Alkaloids as Potent Anticancer Agents: Synthesis, Tyrosinase Inhibition, Mechanism of Action, DFT Calculation, and Molecular Docking Studies

    No full text
    A new series of hybrid compounds with tropinone and thiazole rings in the structure was designed and synthesized as potential anticancer agents. They were tested against human multiple myeloma (RPMI 8226), lung carcinoma (A549), breast adenocarcinoma (MDA-MB-231), and mouse skin melanoma (B16-F10) cell lines. Toxicity was tested on human normal skin fibroblasts (HSF) and normal colon fibroblasts (CCD-18Co). The growth inhibition mechanism of the most active derivative was analyzed through investigation of its effect on the distribution of cell cycle phases and ability to induce apoptosis and necrosis in RPMI 8226 and A549 cancer cells. The tyrosinase inhibitory potential was assessed, followed by molecular docking studies. Compounds 3a–3h show high anticancer activity against MDA-MB-231 and B16-F10 cell lines with IC50 values of 1.51–3.03 µM. Moreover, the cytotoxic activity of the investigated compounds against HSF and CCD-18Co cells was 8–70 times lower than against the cancer cells or no toxicity was shown in our tests, with derivative 3a being particularly successful. The mechanism of action of compound 3a in RPMI 8226 cell was shown to be through induction of cell death through apoptosis. The derivatives show ability to inhibit the tyrosinase activity with a mixed mechanism of inhibition. The final molecular docking results showed for IC50 distinct correlation with experiment
    corecore