496 research outputs found
Temperature and salinity variability in the Greek Seas based on POSEIDON stations time series: preliminary results
Temperature and salinity time series provided by three POSEIDON monitoring stations (buoys) are examined in order to study the seasonal and interannual variability of the water mass characteristics. The sites at Athos (North Aegean Sea), E1M3A (Central Cretan Sea) and Pylos (Eastern Ionian Sea) were chosen, as these buoys provide measurements at various depths, while they represent 3 major basins respectively. The study of the T and S characteristics reveals important seasonal changes and highlights the particular characteristics of each basin. Dense water production in the Northern Aegean is found to be hindered by the presence of the surface Black Sea Water (BSW) mass. On the other hand, the intermediate water mass in the Cretan Sea is shown to be ventilated during the winter season. A significant temperature and salinity increase has been monitored over both the Central Cretan and Eastern Ionian Seas starting from the middle of 2008 and 2009 respectively. This could possibly be attributed to changes in the intermediate water masses of the Eastern Mediterranean, without ruling out the possibility of water mass exchanges between the two basins
Evidence for magnetic clusters in NiV close to the quantum critical concentration
The d-metal alloy NiV undergoes a quantum phase transition from
a ferromagnetic ground state to a paramagnetic ground state as the vanadium
concentration is increased. We present magnetization, ac-susceptibility and
muon-spin relaxation data at several vanadium concentrations near the critical
concentration at which the onset of ferromagnetic order is
suppressed to zero temperature. Below , the muon data reveal a broad
magnetic field distribution indicative of long-range ordered ferromagnetic
state with spatial disorder. We show evidence of magnetic clusters in the
ferromagnetic phase and close to the phase boundary in this disordered
itinerant system as an important generic ingredient of a disordered quantum
phase transition. In contrast, the temperature dependence of the magnetic
susceptibility above is best described in terms of a magnetic quantum
Griffiths phase with a power-law distribution of fluctuation rates of dynamic
magnetic clusters. At the lowest temperatures, the onset of a short-range
ordered cluster-glass phase is recognized by an increase in the muon
depolarization in transverse fields and maxima in ac-susceptibility.Comment: 6 pages, 5 figures, submitted to Proceedings of SCES 201
P-Element Homing Is Facilitated by engrailed Polycomb-Group Response Elements in Drosophila melanogaster
P-element vectors are commonly used to make transgenic Drosophila and generally insert in the genome in a nonselective manner. However, when specific fragments of regulatory DNA from a few Drosophila genes are incorporated into P-transposons, they cause the vectors to be inserted near the gene from which the DNA fragment was derived. This is called P-element homing. We mapped the minimal DNA fragment that could mediate homing to the engrailed/invected region of the genome. A 1.6 kb fragment of engrailed regulatory DNA that contains two Polycomb-group response elements (PREs) was sufficient for homing. We made flies that contain a 1.5kb deletion of engrailed DNA (enΔ1.5) in situ, including the PREs and the majority of the fragment that mediates homing. Remarkably, homing still occurs onto the enΔ1. 5 chromosome. In addition to homing to en, P[en] inserts near Polycomb group target genes at an increased frequency compared to P[EPgy2], a vector used to generate 18,214 insertions for the Drosophila gene disruption project. We suggest that homing is mediated by interactions between multiple proteins bound to the homing fragment and proteins bound to multiple areas of the engrailed/invected chromatin domain. Chromatin structure may also play a role in homing
Keck-I MOSFIRE spectroscopy of compact star-forming galaxies at z2: High velocity dispersions in progenitors of compact quiescent galaxies
We present Keck-I MOSFIRE near-infrared spectroscopy for a sample of 13
compact star-forming galaxies (SFGs) at redshift with star
formation rates of SFR100M y and masses of
log(M/M). Their high integrated gas velocity dispersions of
=230 km s, as measured from emission
lines of H and [OIII], and the resultant
M relation and MM all
match well to those of compact quiescent galaxies at , as measured from
stellar absorption lines. Since log(M/M)
dex, these compact SFGs appear to be dynamically relaxed and more evolved,
i.e., more depleted in gas and dark matter (13\%) than their
non-compact SFG counterparts at the same epoch. Without infusion of external
gas, depletion timescales are short, less than 300 Myr. This discovery
adds another link to our new dynamical chain of evidence that compact SFGs at
are already losing gas to become the immediate progenitors of
compact quiescent galaxies by .Comment: 12 pages, 7 figures, submitted to Ap
A meta-analysis comparing the effectiveness of alternate day fasting, the 5:2 diet, and time-restricted eating for weight loss.
OBJECTIVE
The objective of this meta-analysis was to compare the effectiveness of different intermittent fasting (IF) regimens on weight loss, in the general population, and compare these to traditional caloric energy restriction (CER).
METHODS
Three databases were searched from 2011 to June 2021 for randomized controlled trials (RCTs) that assessed weight loss and IF, including alternate day fasting (ADF), the 5:2 diet, and time-restricted eating (TRE). A random effect network analysis was used to compare the effectiveness between the three regimens. Meta-regression analysis was presented as weighted mean differences of body weight loss.
RESULTS
The exploratory random effects network analysis of 24 RCTs (n = 1768) ranked ADF as the most effective, followed by CER and TRE. The meta-analysis showed that IF regimens resulted in similar weight loss to CER (mean difference 0.26 kg, 95% CI: -0.31 to 0.84; p = 0.37). Compliance was generally high (>80%) in trials shorter than 3 months.
CONCLUSIONS
The present meta-analysis concludes that IF is comparable to CER and a promising alternative for weight loss. Among the three regimens, ADF showed the highest effectiveness for weight loss, followed by CER and TRE. Further well-powered RCTs with longer durations of intervention are required to draw solid conclusions
Evidence for Magnetic Clusters in Ni₁₋ₓVₓ Close to the Quantum Critical Concentration
The d-metal alloy Ni1-xVx undergoes a quantum phase transition from a ferromagnetic ground state to a paramagnetic ground state as the vanadium concentration x is increased. We present magnetization, ac-susceptibility and muon-spin relaxation data at several vanadium concentrations near the critical concentration xc ~ 11.6 % at which the onset of ferromagnetic order is suppressed to zero temperature. Below xc, the muon data reveal a broad magnetic field distribution indicative of a long-range ordered ferromagnetic state with spatial disorder. We show evidence of magnetic clusters in the ferromagnetic phase and close to the phase boundary in this disordered itinerant system as an important generic ingredient of a disordered quantum phase transition. In contrast, the temperature dependence of the magnetic susceptibility above xc is best described in terms of a magnetic quantum Griffiths phase with a power-law distribution of fluctuation rates of dynamic magnetic clusters. At the lowest temperatures, the onset of a short-range ordered cluster-glass phase is recognized by an increase in the muon depolarization in transverse fields and maxima in ac-susceptibility
The MOSFIRE Deep Evolution Field (MOSDEF) Survey: Rest-Frame Optical Spectroscopy for ~1500 H-Selected Galaxies at 1.37 < z < 3.8
In this paper we present the MOSFIRE Deep Evolution Field (MOSDEF) survey.
The MOSDEF survey aims to obtain moderate-resolution (R=3000-3650) rest-frame
optical spectra (~3700-7000 Angstrom) for ~1500 galaxies at 1.37<z<3.80 in
three well-studied CANDELS fields: AEGIS, COSMOS, and GOODS-N. Targets are
selected in three redshift intervals: 1.37<z<1.70, 2.09<z<2.61, and
2.95<z<3.80, down to fixed H_AB (F160W) magnitudes of 24.0, 24.5 and 25.0,
respectively, using the photometric and spectroscopic catalogs from the 3D-HST
survey. We target both strong nebular emission lines (e.g., [OII], Hbeta,
[OIII], 5008, Halpha, [NII], and [SII]) and stellar continuum and absorption
features (e.g., Balmer lines, Ca-II H and K, Mgb, 4000 Angstrom break). Here we
present an overview of our survey, the observational strategy, the data
reduction and analysis, and the sample characteristics based on spectra
obtained during the first 24 nights. To date, we have completed 21 masks,
obtaining spectra for 591 galaxies. For ~80% of the targets we derive a robust
redshift from either emission or absorption lines. In addition, we confirm 55
additional galaxies, which were serendipitously detected. The MOSDEF galaxy
sample includes unobscured star-forming, dusty star-forming, and quiescent
galaxies and spans a wide range in stellar mass (~10^9-10^11.5 Msol) and star
formation rate (~10^0-10^3 Msol/yr). The spectroscopically confirmed sample is
roughly representative of an H-band limited galaxy sample at these redshifts.
With its large sample size, broad diversity in galaxy properties, and wealth of
available ancillary data, MOSDEF will transform our understanding of the
stellar, gaseous, metal, dust, and black hole content of galaxies during the
time when the universe was most active.Comment: Accepted for publication in ApJS; 28 pages, 19 figures; MOSDEF
spectroscopic redshifts available at
http://mosdef.astro.berkeley.edu/Downloads.htm
Comet 162P/Siding Spring: A Surprisingly Large Nucleus
We present an analysis of thermal emission from comet 162P/Siding Spring
(P/2004 TU12) measured during its discovery apparition in 2004 December. The
comet showed no dust coma at this time, so we have sampled emission from the
comet's nucleus. Observations using the Mid-Infrared Spectrometer and Imager
(MIRSI) were performed at NASA's Infrared Telescope Facility, where the peak of
the comet's spectral energy distribution was observed between 8 and 25 microns.
In combination with the three near-IR spectra presented by Campins et al.
(2006, Astron. J. 132, 1346) that show the Wien-law tail of the thermal
emission, the data provide powerful constraints on surface properties of the
nucleus. We find that the nucleus's effective radius is 6.0+/-0.8 km. This is
one of the largest radii known among Jupiter-family comets, which is unusual
considering that the comet was discovered only recently. Its geometric albedo
is 0.059+/-0.023 in the H band, 0.037+/-0.014 in the R band, and 0.034+/-0.013
in the V band. We also find that the nucleus of 162P has little IR beaming, and
this implies that the nucleus has low thermal inertia. Including all near-IR
spectra yields a beaming parameter of 1.01+/-0.20. This result is in agreement
with others showing that cometary nuclei have low thermal inertia and little IR
beaming. If confirmed for many nuclei, the interpretation of radiometry may not
be as problematic as feared.Comment: 17 pages, 4 figures, appearing in The Astronomical Journal, September
2006 issu
Inhibition of Y1 receptor signaling improves islet transplant outcome
Failure to secrete sufficient quantities of insulin is a pathological feature of type-1 and type-2 diabetes, and also reduces the success of islet cell transplantation. Here we demonstrate that Y1 receptor signaling inhibits insulin release in β-cells, and show that this can be pharmacologically exploited to boost insulin secretion. Transplanting islets with Y1 receptor deficiency accelerates the normalization of hyperglycemia in chemically induced diabetic recipient mice, which can also be achieved by short-term pharmacological blockade of Y1 receptors in transplanted mouse and human islets. Furthermore, treatment of non-obese diabetic mice with a Y1 receptor antagonist delays the onset of diabetes. Mechanistically, Y1 receptor signaling inhibits the production of cAMP in islets, which via CREB mediated pathways results in the down-regulation of several key enzymes in glycolysis and ATP production. Thus, manipulating Y1 receptor signaling in β-cells offers a unique therapeutic opportunity for correcting insulin deficiency as it occurs in the pathological state of type-1 diabetes as well as during islet transplantation.Islet transplantation is considered one of the potential treatments for T1DM but limited islet survival and their impaired function pose limitations to this approach. Here Loh et al. show that the Y1 receptor is expressed in β- cells and inhibition of its signalling, both genetic and pharmacological, improves mouse and human islet function.info:eu-repo/semantics/publishe
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