A study on the pathology of abortion

2v.Thesis (M.D.) -- University of Adelaide, Dept. of Obstetrics and Gynaecology, 196

Castleman′s disease with paraneoplastic pemphigus

Castleman′s disease is a rare autoimmune disorder with varied clinical presentations. Castleman′s commonly involves mediastinum and hence it is thoracic in most of the reported cases. Paraneoplastic pemphigus (PNP) and myasthenia gravis can be associated with multicentric Castleman′s disease. Its association with HIV, Kaposi sarcoma, and lymphoma is also well known. We report a rare combination of unicentric, extrathoracic Castleman′s disease with PNP and myasthenia gravis

Seismic Vulnerability Assessment for Various Shapes and Types of Reinforced Concrete Shear Walls in Multi-Storey Buildings

To improve the lateral stiffness and economy, reinforced concrete shear walls are introduced in buildings. This study aims to conduct the seismic assessment of shear walls in a multi-storey building. In this work, various factors are investigated and their performance is compared for various shapes and types of shear walls with respect to strength, displacement, time period, etc. The building considered for the study purpose is a G+12 residential building and is situated in a high seismic zone. The response spectrum analysis of the building is carried out by using the software ETABS. The results show that shear walls not only reduce the seismic forces in a building, but also are advantageous if they are situated in proper positions

IJCM_155A: Socio-demographic profile of patients with Dermatophytoses in tertiary care hospitals in Coastal South India

Background: Dermatophytoses or Dermatophytic infections are diseases characterized by the infection of keratinized tissues. This study was done to study the epidemiological profile and factors associated with Dermatophytosis and the awareness towards the same among patients with such infections. Methodology: This cross-sectional study was carried out in the tertiary hospitals affiliated with Kasturba Medical College, Mangalore. A semi-structured questionnaire was used for the collection of data, which was entered and analysed using SPSS version 25. The results were expressed as proportions. To compare the groups, the Chi-square test was used and p<0.05 was considered statistically significant. Results: Out of the total 118 patients who were included in the study, 57% (n=67) were males. The mean age of the participants was 33.93 years (S.D-12.76). According to our study, among the 118 participants studied, 31% (n=37) of the infected cases belonged to the low-income group (Upper lower), and 63% (n=74) of infected cases belonged to the middle-income group. The study population attributed the occurrence of dermatophytosis to poor skin hygiene (24.5%) followed by occupational exposure (20.1%). A higher proportion, 73% of the patients have increased exposure to water, soil/organic matter, or both. Overall, 90.6% (n=107) were unaware of the complications of the disease and 83.9% (n=99) patients didn’t know of the safety practices followed to prevent it. Conclusion: The occurrence of dermatophytosis is the highest among middle and lower socioeconomic strata people. Poor hygiene, contact with patients and reduced immunity are important risk factors for the disease

Hansen's Neuritis Revisited – A Clinicopathological Study

Introduction: Leprosy affecting the nerve solely or with concomitant skin lesions is not an uncommon condition in clinical practice. It is responsible for extensive morbidity and often poses a diagnostic challenge. This study aims to highlight the clinicopathological features of Hansen's neuritis (HN). Materials and Methods: In this retrospective study, cases of histologically diagnosed HN, from January 2010 to July 2017, were reviewed in the light of clinical features, treatment history, and outcome. Results: There were 18 cases of HN which accounted for 3.97% of total nerve biopsy samples (n = 453) and 0.02% of total histopathology samples (n = 81,013). The male: female ratio was 5:1 in the cases of HN. Age range was 20–79 years with a mean age of 42.4 years (standard deviation: ±14.03). Among the HN cases, there were 13 cases of pure neuritic leprosy (61.1%). Mononeuritis multiplex was the most common finding in the nerve conduction study. Six (33.3%) cases exhibited histological features of borderline tuberculoid leprosy, followed by five (27.8%) cases of mid-borderline features, three (16.7%) cases each of borderline lepromatous and burnt-out HN, and one (5.6%) case of polar tuberculoid leprosy. Lepra bacilli were detected on Fite-Faraco stain in 44.4% cases. Conclusion: Diagnosis of HN depends on astute search for skin lesions, nerve thickening or tenderness, sensory or motor symptoms, histopathological examination, and demonstration of lepra bacilli