218 research outputs found
Critical temperature for the nuclear liquid-gas phase transition (from multifragmentation and fission)
Critical temperature Tc for the nuclear liquid-gas phase transition is
stimated both from the multifragmentation and fission data. In the first
case,the critical temperature is obtained by analysis of the IMF yields in
p(8.1 GeV)+Au collisions within the statistical model of multifragmentation
(SMM). In the second case, the experimental fission probability for excited
188Os is compared with the calculated one with Tc as a free parameter. It is
concluded for both cases that the critical temperature is higher than 16 MeV.Comment: 15 pages, 8 figure
Recoil Studies in the Reaction of 12-C Ions with the Enriched Isotope 118-Sn
The recoil properties of the product nuclei from the interaction of 2.2
GeV/nucleon 12-C ions from Nuclotron of the Laboratory of High Energies (LHE),
Joint Institute for Nuclear Research (JINR) at Dubna with a 118-Sn target have
been studied using catcher foils. The experimental data were analyzed using the
mathematical formalism of the standard two-step vector model. The results for
12-C ions are compared with those for deuterons and protons. Three different
Los Alamos versions of the Quark-Gluon String Model (LAQGSM) were used for
comparison with our experimental data.Comment: 10 pages, 6 figures, submitted to Nucl. Phys.
Measurement of the complete nuclide production and kinetic energies of the system 136Xe + hydrogen at 1 GeV per nucleon
We present an extensive overview of production cross sections and kinetic
energies for the complete set of nuclides formed in the spallation of 136Xe by
protons at the incident energy of 1 GeV per nucleon. The measurement was
performed in inverse kinematics at the FRagment Separator (GSI, Darmstadt).
Slightly below the Businaro-Gallone point, 136Xe is the stable nuclide with the
largest neutron excess. The kinematic data and cross sections collected in this
work for the full nuclide production are a general benchmark for modelling the
spallation process in a neutron-rich nuclear system, where fission is
characterised by predominantly mass-asymmetric splits.Comment: 18 pages, 14 figure
Critical Temperature for the Nuclear Liquid-Gas Phase Transition
The charge distribution of the intermediate mass fragments produced in p (8.1
GeV) + Au collisions is analyzed in the framework of the statistical
multifragmentation model with the critical temperature for the nuclear
liquid-gas phase transition as a free parameter. It is found that
MeV (90% CL).Comment: 4 pages, 3 figures, published in Phys. Rev.
Sanitary Protection of the Territories within the Frames of Sanitary-Epidemiological Welfare Provision
Demonstrated is the structural and functional interrelation between sanitary protection of the territories, epidemiological monitoring, and the state sanitary-epidemiological surveillance. Sanitary protection of the territories (SPT) of the Russian Federation is a separate focus area authorizing sanitary prophylactic (anti-epidemic) activities, with a self-sustained sub-goal. It combines individual roles appertained to epidemiological monitoring and to federal sanitary-epidemiological surveillance, only in reference to a particular item - emergency situation in the sphere of sanitary-epidemiological welfare of the population. Specificity of the SPT is a balance between functionality and capacity of the monitoring, surveillance and control. Legislative and regulatory legal acts, which concern sanitary protection of the territory, provide the means for defining its basic organizational principles: country-wide activities, self-sufficiency and self-support of the Rospotrebnadzor, three-level hierarchical system, and information exchange
Immunohistochemical evaluation of Ki-67, Cyclin D1 and β-catenin expression in the subtypes of triple negative breast cancer
Aim. To evaluate the expression levels of Ki-67 and cyclin D1 and β-catenin in the subtypes of triple negative breast cancer.
Methods. The study was conducted on the surgical material from 60 patients of clinical stage 2A (T1N1M0 or T2N0M0) who were treated at the Rostov Research Institute of Oncology from 2012 to 2015. For immunohistochemistry, antibodies to estrogen and progesterone receptors, cytokeratins 5/6, Ki-67, cyclin D1, β-catenin, HER2/neu and EGFR proteins were used.
Results. Triple negative breast cancer with the signs of basal epithelium was found to have a significantly higher expression level of Ki-67 compared to non-basal-like one. In some part of triple negative breast cancer samples overexpression of cyclin D1 was observed. The high level of cyclin D1 in the basal-like subtype was less common than in the subtypes without the signs of basal epithelium, but its average value was significantly higher. In triple negative cancer with cyclin D1 overexpression, the loss of β-catenin on the cell membrane and its abnormal accumulation in the cytoplasm was significantly more frequent. β-catenin translocation into the cell nucleus was observed only in basal-like triple negative cancer, and 2 times more often in case of cyclin D1 overexpression.
Conclusion. In triple negative breast cancer tumors with overexpression of cyclin D1 and abnormal expression of β-catenin are observed in some cases; these biomarkers can be considered as potential therapeutic targets for this group of tumors
Improvement of the Normative-Regulatory Framework Concerning Anti-Epidemic Procedures for Works with Infectious Disease Agents in Mobile Laboratories of Specialized Anti-Epidemic Teams (SAET)
Carried out is a range of investigations aimed at the improvement of the anti-epidemic procedures for works with infectious disease agents (herein biological safety provision) in mobile laboratories of specialized anti-epidemic teams (SAET). Evaluation of the operational experience of stationary and field laboratories, as well as comparative analysis of the national safety requirements for works with pathogenic biological agents and WHO international regulations in the sphere of biological safety provision in laboratories, has made it possible to outline common for all types of microbiological laboratories principles for biosafety provision. With due consideration of these principles formulated are the core requirements for the provision of biological safety of SAET activities. Based on the results of biorisk and biohazard assessment which have to do with innovative mobile laboratories, worked out is a system of anti-epidemic procedures aimed towards establishment of the conditions that offer as low as practically achievable level of risk for personnel of SAET mobile laboratories, for population and human environment too. These practices, designed for biological safety provision among the personnel of mobile laboratories (ML), have been played back in a number of standard operational procedures. With a view to establishing of the environment with acceptable level of biorisk for the personnel and population when ML are used for various purposes and in various contingencies (in full force, single unit or several modules), worked out are the algorithms of decision-making support as regards selection of modules and optional accessories. However, there is a need for emergency response plans and training programs for the personnel on the provision of biosafety in ML to ensure and maintain acceptable level of biorisk connected with ML functioning
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