A historical study of the San Francisco Council of Churches senior citizens project

The purpose of this study is to give a historical account of the San Francisco Council of Churches Senior Citizen Projects. Also, the following will be discussed: Why is research being conducted in the areas of senior citizens? What are the problems of the senior citizen? What is this Agency doing for the senior citizens in San Francisco

Finding strong lenses in CFHTLS using convolutional neural networks

We train and apply convolutional neural networks, a machine learning technique developed to learn from and classify image data, to Canada-France-Hawaii Telescope Legacy Survey (CFHTLS) imaging for the identification of potential strong lensing systems. An ensemble of four convolutional neural networks was trained on images of simulated galaxy-galaxy lenses. The training sets consisted of a total of 62,406 simulated lenses and 64,673 non-lens negative examples generated with two different methodologies. The networks were able to learn the features of simulated lenses with accuracy of up to 99.8% and a purity and completeness of 94-100% on a test set of 2000 simulations. An ensemble of trained networks was applied to all of the 171 square degrees of the CFHTLS wide field image data, identifying 18,861 candidates including 63 known and 139 other potential lens candidates. A second search of 1.4 million early type galaxies selected from the survey catalog as potential deflectors, identified 2,465 candidates including 117 previously known lens candidates, 29 confirmed lenses/high-quality lens candidates, 266 novel probable or potential lenses and 2097 candidates we classify as false positives. For the catalog-based search we estimate a completeness of 21-28% with respect to detectable lenses and a purity of 15%, with a false-positive rate of 1 in 671 images tested. We predict a human astronomer reviewing candidates produced by the system would identify ~20 probable lenses and 100 possible lenses per hour in a sample selected by the robot. Convolutional neural networks are therefore a promising tool for use in the search for lenses in current and forthcoming surveys such as the Dark Energy Survey and the Large Synoptic Survey Telescope.Comment: 16 pages, 8 figures. Accepted by MNRA

Heat transfer coefficient saturation in superconducting Nb tunnel junctions contacted to a NbTiN circuit and an Au energy relaxation layer

In this paper we present the experimental realization of a Nb tunnel junction connected to a high-gap superconducting NbTiN embedding circuit. We investigate relaxation of nonequilibrium quasiparticles in a small volume Au layer between the Nb tunnel junction and the NbTiN circuit. We find a saturation in the effective heat-transfer coefficient consistent with a simple theoretical model. This saturation is determined by the thickness of the Au layer. Our findings are important for the design of the ideal Au energy relaxation layer for practical SIS heterodyne mixers and we suggest two geometries, one, using a circular Au layer and, two, using a half-circular Au layer. Our work is concluded with an outlook of our future experiments.Comment: Applied Superconductivity Conference 201

A 490 GHz planar circuit balanced Nb-Al2_\mathbf{2}O3_{\mathbf{3}}-Nb quasiparticle mixer for radio astronomy: Application to quantitative local oscillator noise determination

This article presents a heterodyne experiment which uses a 380-520 GHz planar circuit balanced Nb-$\mathrm{Al_2O_3}$-Nb superconductor-insulator-superconductor (SIS) quasiparticle mixer with 4-8 GHz instantaneous intermediate frequency (IF) bandwidth to quantitatively determine local oscillator (LO) noise. A balanced mixer is a unique tool to separate noise at the mixer's LO port from other noise sources. This is not possible in single-ended mixers. The antisymmetric IV characteristic of a SIS mixer further helps to simplify the measurements. The double-sideband receiver sensitivity of the balanced mixer is 2-4 times the quantum noise limit $h\nu/k_B$ over the measured frequencies with a maximum LO noise rejection of 15 dB. This work presents independent measurements with three different LO sources that produce the reference frequency but also an amount of near-carrier noise power which is quantified in the experiment as a function of the LO and IF frequency in terms of an equivalent noise temperature $T_{LO}$. In a second experiment we use only one of two SIS mixers of the balanced mixer chip, in order to verify the influence of near-carrier LO noise power on a single-ended heterodyne mixer measurement. We find an IF frequency dependence of near-carrier LO noise power. The frequency-resolved IF noise temperature slope is flat or slightly negative for the single-ended mixer. This is in contrast to the IF slope of the balanced mixer itself which is positive due to the expected IF roll-off of the mixer. This indicates a higher noise level closer to the LO's carrier frequency. Our findings imply that near-carrier LO noise has the largest impact on the sensitivity of a receiver system which uses mixers with a low IF band, for example superconducting hot-electron bolometer (HEB) mixers.Comment: 13 pages, 8 figures, 2 tables, see manuscript for complete abstrac

The complex relationship between pediatric cardiac surgical case volumes and mortality rates in a national clinical database

ObjectiveWe sought to determine the association between pediatric cardiac surgical volume and mortality using sophisticated case-mix adjustment and a national clinical database.MethodsPatients 18 years of age or less who had a cardiac operation between 2002 and 2006 were identified in the Society of Thoracic Surgeons Congenital Heart Surgery Database (32,413 patients from 48 programs). Programs were grouped by yearly pediatric cardiac surgical volume (small, <150; medium, 150–249; large, 250–349; and very large, ≥350 cases per year). Logistic regression was used to adjust mortality rates for volume, surgical case mix (Aristotle Basic Complexity and Risk Adjustment for Congenital Heart Surgery, Version 1 categories), patient risk factors, and year of operation.ResultsWith adjustment for patient-level risk factors and surgical case mix, there was an inverse relationship between overall surgical volume as a continuous variable and mortality (P = .002). When the data were displayed graphically, there appeared to be an inflection point between 200 and 300 cases per year. When volume was analyzed as a categorical variable, the relationship was most apparent for difficult operations (Aristotle technical difficulty component score, >3.0), for which mortality decreased from 14.8% (60/406) at small programs to 8.4% (157/1858) at very large programs (P = .02). The same was true for the subgroup of patients who underwent Norwood procedures (36.5% [23/63] vs 16.9% [81/479], P < .0001). After risk adjustment, all groups performed similarly for low-difficulty operations. Conversely, for difficult procedures, small programs performed significantly worse. For Norwood procedures, very large programs outperformed all other groups.ConclusionThere was an inverse association between pediatric cardiac surgical volume and mortality that became increasingly important as case complexity increased. Although volume was not associated with mortality for low-complexity cases, lower-volume programs underperformed larger programs as case complexity increased

Genome-wide profiling of human cap-independent translation-enhancing elements.

We report an in vitro selection strategy to identify RNA sequences that mediate cap-independent initiation of translation. This method entails mRNA display of trillions of genomic fragments, selection for initiation of translation and high-throughput deep sequencing. We identified &gt;12,000 translation-enhancing elements (TEEs) in the human genome, generated a high-resolution map of human TEE-bearing regions (TBRs), and validated the function of a subset of sequences in vitro and in cultured cells

Constraining the geometry of the reflection nebula NGC 2023 with [O I]: Emission & Absorption

We have mapped the NGC 2023 reflection nebula in the 63 and 145 micron transitions of [O I] and the 158 micron [C II] spectral lines using the heterodyne receiver upGREAT on SOFIA. The observations were used to identify the diffuse and dense components of the PDR traced by the [C II] and [O I] emission, respectively. The velocity-resolved observations reveal the presence of a significant column of low-excitation atomic oxygen, seen in absorption in the [O I] 63 micron spectra, amounting to about 20-60% of the oxygen column seen in emission in the [O I] 145 micron spectra. Some self-absorption is also seen in [C II], but for the most part it is hardly noticeable. The [C II] and [O I] 63 micron spectra show strong red- and blue-shifted wings due to photo evaporation flows especially in the southeastern and southern part of the reflection nebula, where comparison with the mid- and high-J CO emission indicates that the C+ region is expanding into a dense molecular cloud. Using a two-slab toy model the large-scale self-absorption seen in [O I] 63 micron is readily explained as originating in foreground low-excitation gas associated with the source. Similar columns have also been observed recently in other Galactic photon-dominated-regions (PDRs). These results have two implications: for the velocity-unresolved extra-galactic observations this could impact the use of [O I] 63 micron as a tracer of massive star formation and secondly the widespread self-absorption in [O I] 63 micron leads to underestimate of the column density of atomic oxygen derived from this tracer and necessitates the use of alternative indirect methods.Comment: Accepted for publication in MNRA