Association of polycystic ovary syndrome and a non-dipping blood pressure pattern in young women

OBJECTIVE: The association between polycystic ovarian syndrome and increased cardiovascular disease risk is still a controversial issue. In light of data documenting some common pathways or common end-points, the present study was undertaken to determine whether there is a relationship between sleep blood pressure pattern disturbances and polycystic ovarian syndrome in young women. METHOD: The daytime and nighttime ambulatory blood pressures (BPs) were determined for each subject, according to the actual waking and sleeping times recorded in their individual diaries, in this cross-sectional study. RESULTS: The study group comprised 168 women (mean age: 25.7±5.5) diagnosed with polycystic ovarian syndrome, while the control group included 52 age- and BMI-matched healthy subjects (mean age: 26.1±5.4). When nocturnal BP declines very little or not at all, with the BP falling less than 10% during sleep compared with waking values, this pattern is classified as a non-dipping BP pattern. However, the non-dipping pattern of BP changes was significantly more common in polycystic ovarian syndrome patients compared to the control group (p<0.01). The prevalence of a non-dipping BP pattern was 43.4% (73 patients) in polycystic ovarian syndrome patients and 3.9% (2 patients) in the control group. CONCLUSION: Our cross-sectional study revealed that a non-dipping BP pattern is highly prevalent in polycystic ovarian syndrome patients, even if they are young and non-obese

Crystal Structure, Spectroscopic Properties and Density Functional Theory Study of (Z)-1-[(2,4-Dimethoxyphenylamino)methylene]naphthalen-2(1H)-one

WOS: 000332118000003The Schiff base (Z)-1-[(2,4-dimethoxyphenylamino)methylene]naphthalen-2(1H)-one was synthesized from the reaction of 2-hydroxy-1-naphthaldehyde with 2,4-dimethoxyaniline. The title compound has been characterized by FT-IR, UV-Vis and, X-ray single-crystal techniques. The present X-ray investigation shows that the compound exists in the keto-amine tautomeric form. Molecular geometry and vibrational frequencies of the compound in the ground state have been calculated using the density functional theory (DFT) with 6-311G(d, p) basis set and compared with the experimental data. The calculated results show that the optimized geometry is compatible with the crystal structure and the theoretical vibrational frequencies are in good agreement with the experimental values. Besides, molecular electrostatic potential (MEP), frontier molecular orbital analysis (HOMO-LUMO) and non-linear optical (NLO) properties of the compound were investigated using the same theoretical calculations

(E)-N-[(2-Ethoxynaphthalen-1-yl)methylidene]-2-ethylaniline

In the title compound, C21H21NO, the dihedral angle between the naphthalene ring system and the benzene ring is 64.61(6)°. The molecular structure is stabilized by an intramolecular C-H?N hydrogen bond

BLOOD LIPIDS, DIABETIC COMPLICATIONS AND THE PHYSICIAN ATTITUDES ON DYSLIPIDEMIA TREATMENT; DATA FROM THE TURKISH NATIONWIDE SURVEY OF GLYCEMIC AND OTHER METABOLIC PARAMETERS OF PATIENTS WITH DIABETES

86th Congress of the European-Atherosclerosis-Society (EAS) -- MAY 05-08, 2018 -- Lisbon, PORTUGALWOS: 000442512600170…European Atherosclerosis So