Liquid-liquid extraction of transition metal cations by glyoximes and their macrocyclic glyoxime ether derivatives

Liquid-liquid extraction of various alkalis (Li+, Na +, K+, and Cs+), transition metals (Co 2+, Ni2+, Cu2+, Zn2+, Cd 2+, and Hg2+), and Pb2+ cations with phenylglyoxime (L1), p-tolylglyoxime (L2), N′-(4′-Benzo[15-crown-5]) phenylaminoglyoxime (L3), and N′-(4′-Benzo[15-crown-5])-p- tolylaminoglyoxime (L4) from the aqueous phase into the organic phase was carried out. For comparison, the corresponding two glyoximes and their macrocyclic glyoxime ether derivatives were also examined. Crown ether groups having ligands (L3, L4) carry especially Na+ cation from aqueous phase to organic phase. The extraction equilibrium constants (K ex) for complexes of ligands with Cu2+ and Hg2+ metal picrates between dichloromethane and water have been determined at 25°C. The values of the extraction constants (log K ex) were determined to be 12.27, 13.37, 12.94, and 12.39 for Cu2+ and 10.29, 10.62, 11.53, and 11.97 for Hg2+ with L1-L4, respectively. © 2013 Nazan Karapinar et al

The synthesis and Ni(II), Co(II), Cu(II), Cd(II), and Zn(II) complexes of two new unsymmetrical vic-dioximes

Two new substituted aminoglyoximes, N-(4-ethylphenyl)amino-amphi-glyoxime [(LH2)-H-1] and N-(4-ethylphenyl)amino-anti-glyoxime [(LH2)-H-2], have been synthesized from amphi-chloroglyoxime and anti-chloroglyoxime and 4-ethylanilin. The preparation of nickel(II), cobalt(II), copper(H), zinc(II) and cadmium(II) complexes of the amphi- and anti-isomers of these ligands are described. All of these complexes are insoluble in common solvents. IR spectra and elemental analyses data of these complexes are given. Also, mass and H-1 NMR spectra of these ligands are presented

Synthesis and characterization of substituted aminobiphenylglyoximes and their complexes with some transition metals

In this study, four different new vic-dioximates, [L1H 2] N-(4-ethylphenyl)amino-biphenylglyoxime, [L2H 2] N-(4-butylphenyl)aminobiphenylglyoxime, [L3H 2] N-(4-aminoacetanilide)aminobiphenylglyoxime, and [L 4H2] N-(thiazol-2-yl-aminobiphenylglyoxime are synthesized from anti-4-biphenylchloroglyoxime and the corresponding substituted aromatic amines. The Co(II), Ni(II), and Cu(II) complexes of these ligands are prepared. The structures of these new ligands and their complexes are proposed based upon IR, 1H, and 13C NMR spectral data, mass spectroscopy, magnetic susceptibility measurement, and elemental analyses. © Nauka/Interperiodica 2006

The removal of heavy metal cations by natural zeolites

In this study, the adsorption behavior of natural (clinoptilolite) zeolites with respect to Co 2+ , Cu 2+ , Zn 2+ , and Mn 2+ has been studied in order to consider its application to purity metal finishing wastewaters. The batch method has been employed, using metal concentrations in solution ranging from 100 to 400 mg/l. The percentage adsorption and distribution coefficients (K d ) were determined for the adsorption system as a function of sorbate concentration. In the ion exchange evaluation part of the study, it is determined that in every concentration range, adsorption ratios of clinoptilolite metal cations match to Langmuir, Freundlich, and Dubinin-Kaganer-Radushkevich (DKR) adsorption isotherm data, adding to that every cation exchange capacity metals has been calculated. It was found that the adsorption phenomena depend on charge density and hydrated ion diameter. According to the equilibrium studies, the selectivity sequence can be given as Co 2+ > Cu 2+ > Zn 2+ > Mn 2+ . These results show that natural zeolites hold great potential to remove cationic heavy metal species from industrial wastewater. © 2004 Elsevier Inc. All rights reserved

Seasonal variations of NOM composition and their reactivity in a low humic water

Natural organic matter (NOM) and its potential to form disinfection by-products (DBPs) during water treatment are of great public health concern. Understanding the seasonal changes in NOM composition and their reactivity in DBP formation could lead to a better treatment of drinking water and a more consistent water quality. NOM from the Terkos Lake was fractionated and characterized by XAD resin adsorption and ultrafiltration (UF) techniques during four different seasons within a year. XAD fraction analysis indicates that the HPI (38%) and the TPI (21%) were the dominant chemical fractions as DOC masses across the sampling period. Moreover, the fractions contributing to the most UV254 absorbance were HPO, which accounted for more than 72% of total UV254. It was found that the percentages of UV254 of HPI and TPI showed significant amount of variation with coefficients of variation of 48% (HPI) and 35% (TPI), respectively. Moreover, it was concluded that the HPO fraction was the primary THM precursor, which contributed more than 48%, and while the primary fraction of HAA precursors was found to be TPI, accounting for more than 47% of total HAAFP with exceptions in January 2011. As obviously seen in this study, the hydrophobic constituents in Terkos Lake water are on the low end of the spectrum in terms of their reactivity to form HAAs. In the context of THM reactivity, the physical properties (i.e., moleculer size) of Terkos Lake NOM are more important than their chemical properties (i.e., aromaticity). On the other hand, the predominant fraction as the source of HAAs precursors was found to be with the TPI and HPI chemical fractions. © 2013 American Institute of Chemical Engineers

Juvenile Myelomonocytic Leukemia in Turkey: A Retrospective Analysis of Sixty-five PatientsÖzlem Tüfekçi1

Objective: This study aimed to define the status of juvenile myelomonocytic leukemia (JMML) patients in Turkey in terms of time of diagnosis, clinical characteristics, mutational studies, clinical course, and treatment strategies. Materials and Methods: Data including clinical and laboratory characteristics and treatment strategies of JMML patients were collected retrospectively from pediatric hematology-oncology centers in Turkey. Results: Sixty-five children with JMML diagnosed between 2002 and 2016 in 18 institutions throughout Turkey were enrolled in the study. The median age at diagnosis was 17 months (min-max: 2-117 months). Splenomegaly was present in 92% of patients at the time of diagnosis. The median white blood cell, monocyte, and platelet counts were 32.9x109/L, 5.4x109/L, and 58.3x109/L, respectively. Monosomy 7 was present in 18% of patients. JMML mutational analysis was performed in 32 of 65 patients (49%) and PTPN11 was the most common mutation. Hematopoietic stem cell transplantation (HSCT) could only be performed in 28 patients (44%), the majority being after the year 2012. The most frequent reason for not performing HSCT was the inability to find a suitable donor. The median time from diagnosis to HSCT was 9 months (min-max: 2-63 months). The 5-year cumulative survival rate was 33% and median estimated survival time was 30+-17.4 months (95% CI: 0-64.1) for all patients. Survival time was significantly better in the HSCT group (log-rank p=0.019). Older age at diagnosis (>2 years), platelet count of less than 40x109/L, and PTPN11 mutation were the factors significantly associated with shorter survival time. Conclusion: Although there has recently been improvement in terms of definitive diagnosis and HSCT in JMML patients, the overall results are not satisfactory and it is necessary to put more effort into this issue in Turkey