Evaluation of preoperative anxiety levels of patients undergoing elective surgery in COVID-19 pandemic

COVID-19 önlemleri alınarak elektif cerrahilerin yeniden başlatıldığı pandemi sürecinde elektif cerrahi uygulanacak hastaların preoperatif anksiyete düzeylerinin ve anksiyete seviyelerini etkileyen faktörlerin değerlendirilmesi amaçlandı. 18-75 yaş grubu elektif cerrahi uygulanacak 450 hasta dahil edildi. Yazılı onamları alınan hastalar preoperatif dönemde değerlendirildi. Demografik verileri, eğitim durumu, medikal geçmişi, anestezi ve cerrahi deneyimleri sorgulandı. COVID-19 hakkında soruların olduğu anket formu ile yirmişer maddelik durumluk ve sürekli kaygı ölçeklerinden oluşan Spielberger Durumluk-Sürekli Anksiyete Ölçeği (STAI) hastalar tarafından dolduruldu. Durumluk (STAII) ve sürekli (STAI-II) kaygı ölçeklerinde büyük puan yüksek anksiyete seviyesini, küçük puan ise düşük anksiyete seviyesini belirtir. 49.26±15.51 yaş ortalaması olan hastaların ortalama anksiyete düzeyi STAI-I’de 41.46±8.43, STAI-II’de 37.79±9.73 olarak bulundu. Opere edilen kliniklere göre hastaların STAI-I puanları orta düzeyde anksiyete, STAI-II puanları ise hafif düzeyde anksiyete ile uyumluydu. Hastaların yaşı ile STAI-I arasında negatif yönde korelasyon görüldü (r=-0.52, p=0.136), STAI-II’de ise yaş ile pozitif korelasyon saptandı (r=0.22, p=0.321). Cinsiyet, eğitim durumu, geçirilmiş ameliyat öyküsü ve anestezi deneyimi açısından değerlendirildiğinde preoperatif STAI-I ve II puanlarında farklılık saptanmadı. COVID-19 pandemisi hakkında yeterli bilgi sahibi olmadığını düşünen hastaların (%17,6) STAI-I ve STAI-II puanları anlamlı yüksekti (p= 0.000, p= 0.001). Ailesinde geçirilmiş COVID-19 enfeksiyonu bulunan hastaların STAI-I ve II puanları ile diğer hastaların puanları benzerdi (p=0.76, p=0.91). Hastane yatışında COVID-19 ile enfekte olma tedirginliği bulunan hastaların (287 hasta, %63.8) STAI-I puanı hastanede COVID-19’a yakalanmaktan korkmayanlara (163 hasta, %36.2) göre yüksek bulundu (p=0.05). Postoperatif dönemde hastane yatışı sırasında COVID-19 ile enfekte olan hasta olmadı. Elektif cerrahi geçirecek hastalarda COVID-19 pandemisinde preoperatif anksiyete düzeyleri artmıştır. Preoperatif dönemde hastalara COVID-19 ile ilgili rutin bilgilendirme yapılmasının ve alınacak önlemlerden bahsedilmesinin anksiyete düzeyini azaltmada faydalı olacağı düşüncesindeyiz.We aimed to evaluate the pre-operative anxiety levels of patients and the factors affecting their anxiety levels who will undergo elective surgery during the pandemic process in which elective surgeries are restarted by taking COVID-19 precautions. 450 patients between 18-75 years old, will undergo elective surgery were included in the study. Patients, whose written consents were obtained, were evaluated in the preoperative period. The demographic data, educational status, medical history, anesthesia and surgical experiences of the patients were questioned. A questionnaire containing questions about COVID-19 and the Spielberger State-Trait Anxiety Inventory (STAI) consisting of twenty-item state and trait anxiety scales were filled in by the patients. On the state (STAI-I) and trait (STAI-II) anxiety scales, a large score indicates a high level of anxiety, and a small score indicates a low level of anxiety. The average anxiety level of the patients with a mean age of 49.26 ± 15.51 years was found as 41.46 ± 8.43 in STAI-I and 37.79 ± 9.73 in STAI-II. According to the type of operation, STAI-I scores of the patients were compatible with moderate anxiety, and STAI-II scores were compatible with mild anxiety. There was a negative correla tion between the age of patients and STAI-I scores (r=-0.52, p=0.136). and a positive correlation was found between STAI-II and the age of patients (r = 0.22, p = 0.321). No difference was found in preoperative STAI-I and II scores when evaluated in terms of gender, educational status, history of previous surgery and anesthesia experiences. STAI-I and STAI-II scores were significantly higher in the patients (17.6%) that thought they didn’t have enough information about the pandemic (p = 0.000, p = 0.001). The STAI-I and II scores of the patients with a family history of COVID-19 infection were similar with the other patients (p = 0.76, p = 0.91). The STAI-I scores of the patients (287 pati ents, 63.8%) who were worried about being infected with COVID-19 during hospitalization were found to be higher than those who were not afraiding of infected with COVID-19 (163 patients, 36.2%) (p = 0.05). There was no patient infected with COVID-19 during hospitalization. Preoperative anxiety levels have increased in patients undergoing elective surgery in COVID-19 pandemic. We think that informing patients about COVID-19 routinely and talking about the precautions to be taken in the preoperative period will be beneficial in reducing their anxiety levels

Effect of supportive care on the psychosocial health status of women who had a miscarriage

Purpose This study aims to determine the effect of individualized care provided based on Swanson's Caring Theory on the grief, depression, anxiety, and stress levels of women who had a miscarriage

Biomechanical and histological effects of intra-articular hyaluronic acid on anterior cruciate ligament in rats

WOS: 000268430600006PubMed: 19464776Background: The histologic and biomechanical effects of intra-articular hyaluronic acid on the anterior cruciate ligaments of rats were investigated. Methods: Thirty rats were divided into three groups, i.e., the hyaluronic acid group, saline group, and control group. The hyaluronic acid and saline groups received a total of four intra-articular injections, whereas no injection was administered to the control group. The hyaluronic acid group was injected with 50 mu g (0.05 cc) hyaluronic acid, and the saline group was injected with 50 mu l (0.05 cc) of 0.9% sodium chloride solution. All of the rats were sacrificed on day 29 and the femur-anterior cruciate ligament-tibia complexes from the right knees were prepared, tested mechanically, and evaluated histologically. Findings: The mode of failure involved the midsubstance of the anterior cruciate ligament in all the specimens. There were no statistically significant differences in the stiffness and ultimate load to failure values between the three groups (P > 0.05). The energy to failure values were evaluated and there was no statistically significant difference between the groups (P = 0.064, chi-square = 3.43). In the histologic analyses, there was a significant difference in the hyalinization values between the hyaluronic acid and saline groups (P = 0.029) and between the hyaluronic acid group and control groups (P = 0.029). Interpretation: The present study shows that intra-articularly delivered hyaluronic acid has no statistically significant effect on the tensile strength of the rat anterior cruciate ligament. Although hyalinization was increased, no difference was found on the other markers for degenerative changes. We conclude that intra-articular hyaluronic acid injections can be performed safely, although the use of a precise injection technique is recommended. (C) 2009 Elsevier Ltd. All rights reserved

Bir göçmenin gözünden Bulgaristan'dan Türkiye'ye göç

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2014.This work is a student project of the The Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.by Özer, Abdürrahim

Zero-valent iron nanoparticles containing nanofiber scaffolds for nerve tissue engineering

Regeneration of nerve tissue is a challenging issue in regenerative medicine. Especially, the peripheral nerve defects related to the accidents are one of the leading health problems. For large degeneration of peripheral nerve, nerve grafts are used in order to obtain a connection. These grafts should be biodegradable to prevent second surgical intervention. In order to make more effective nerve tissue engineering materials, nanotechnological improvements were used. Especially, the addition of electrically conductive and biocompatible metallic particles and carbon structures has essential roles in the stimulation of nerves. However, the metabolizing of these structures remains to wonder because of their nondegradable nature. In this study, biodegradable and conductive nerve tissue engineering materials containing zero-valent iron (Fe) nanoparticles were developed and investigated under in vitro conditions. By using electrospinning technique, fibrous mats composed of electrospun poly(epsilon-caprolactone) (PCL) nanofibers and Fe nanoparticles were obtained. Both electrical conductivity and mechanical properties increased compared with control group that does not contain nanoparticles. Conductivity of PCL/Fe5 and PCL/Fe10 increased to 0.0041 and 0.0152 from 0.0013 Scm(-1), respectively. Cytotoxicity results indicated toxicity for composite mat containing 20% Fe nanoparticles (PCL/Fe20). SH-SY5Y cells were grown on PCL/Fe10 best, which contains 10% Fe nanoparticles. Beta III tubulin staining of dorsal root ganglion neurons seeded on mats revealed higher cell number on PCL/Fe10. This study demonstrated the impact of zero-valent Fe nanoparticles on nerve regeneration. The results showed the efficacy of the conductive nanoparticles, and the amount in the composition has essential roles in the promotion of the neurites