Bıldırcın rasyonlarına katılan farklı yağ kaynaklarının büyüme, karkas özellikleri ve serum biyokimyasal parametrelere etkisi

A six weeks long study trial was conducted on Japanese quails to evaluate the growth performance, carcass traits, some blood parameters and oxidative status when different vegetable oils were supplemented through diet. A total of 400, 3 days old, Japanese quails, were randomly divided into four different groups and each consisting of 100 quails. Each of the main group was further divided into five replicates and each replicate was composed of 20 quails. Soybean oil, sunflower oil, safflower oil and olive oil was supplemented to experimental diets separately at level of 3%. The results showed that there were no changes in terms of growth performance and carcass traits as well as alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, total protein, triglyceride and cholesterol levels in all experimental groups with soybean oil, sunflower oil, safflower oil and olive oil supplementation (p>0.05). However it was observed that, the serum malondialdehyde level was decreased, whereas serum antioxidant activity level was significantly increased (p0.05). Buna karşın aspir yağlı grupta serum malondialdehit düzeyinin azalırken, serum antioksidan aktivite düzeyinin arttığı belirlendi (p<0.05). Araştırmada bıldırcın rasyonlarına soya, ayçiçeği, aspir ve zeytin yağı katımının büyüme performansı, karkas özellikleri, serum biyokimyasal parametreler ve göğüs etindeki antioksidan duruma herhangi bir zarar verici ya da fayda sağlayıcı bir etkisi olmadığı sonucuna varılabilir. Ayrıca, bıldırcınlarda serum lipit oksidasyonunun önlenmesinde aspir yağı katımının daha etkili olabileceği de ifade edilebilir. Anahtar Kelimeler: Bıldırcın, bitkisel yağ, büyüme performansı, oksidasyon

Sefîne-i Nefîse-i Mevlevîyân ve Mevlevîler

YÖK Tez ID: 532522Sefîne-i Nefîse-i Mevlevîyân, Mustafa Sâkıb Dede'nin 3 cilt halinde Mısır'da h. 1283 m. 1866 yılında basılmış eseridir. I. cildi, Menâkıb-ı Sipehsâlâr ile başlayıp Menâkıbü'l-Ârifîn ile devam eden süreçte Konya Mevlevîhânesi'nde şeyhlik yapan meşahinin ve inas tarafından Mevlânâ soyuna mensup Mevlevî erkek ve kadınların biyografilerini içeren bir eserdir. Bu çalışmamızda öncelikle I. cilt üzerinde incelemelerde bulunduk ve bu biyografileri esere bağlı kalarak sadeleştirerek, özet halinde günümüz Türkçesine aktarmaya çalıştık. Mevlevîler ile ilgili yazılmış olan eserleri de inceleyerek karşılaştırmalarla bir neticeye ulaşılmıştır. Giriş kısmında, Mevlevîlik ve onun gelişim süreci hakkında bilgi verdikten sonra; 1. ve 2. bölümde Mustafa Sâkıb Dede ve Sefîne-i Nefîse-i Mevlevîyân ile ilgili bilgiler paylaşıp eserdeki şahıslarla ilgili bölümlere geçmeden önce yazar ve eserle ilgili bilgiler aktardık. 3. bölümde ise Sefîne-i Nefîse-i Mevlevîyân adlı eserin I. cildinde adı geçen 54 Mevlevî'nin, 4. bölümde ise 4 hanım Mevlevînin biyografisini günümüz Türkçe'sine aktarırken sadeleştirerek özetledik. Bu şahısların biyografi çevirilerini yaparken adı geçen şahıslarla ilgili diğer kaynaklarda aktarılan bilgileri ekleyerek karşılaştırma imkânı sunduk. Anahtar Kelimeler: Sefîne-i Nefîse-i Mevlevîyân, Mustafa Sâkıb Dede, Mevlevî şahıslar.Sefîne-i Nefîse-i Mevleviyan, Mustafa Sakib Dede's 3 volume is printed in Hijri. 1283 in Egypt. First volume of the book, starting with Manaqib Sipehsalar and continued with Menaqib Al- Arifin which contains elder and superior persons in Mowlana houses, men and women who by mother is ancestor of the Mowlana's in Konya. In our research, we study first volume of the book and generally translated the bibliography and investigate the books which have been written about the Mawlawiyah and also reached to conclusion by examining the comparisons. In the introduction, we give information about Mawlawiyah and process of its development, then in first and second section; Sakib Dede and Sefîne-i Nefîse-i Mevleviyan and give information about the authors and titles before translating the book reported. In third section we translate 58 Mowlawi's biblography which mentioned in first volume of the book. When these name's bibliography translated, we give opportunity to comparison by adding information that is transferred in other sources about these names. Key Worsd: Sefine-i Nefise-i Mevleviyan, Mustafa Sakib Dede, Mowlawi person

Examining the Factors That Affect Classroom Teacher’S Attitudes Towards the Mainstreamed Students

DergiPark: 371192trakyasobedSon yıllarda Türkiye’de kaynaştırma eğitimiuygulamaları büyük önem kazanmaktadır. Başarılı bir kaynaştırma eğitiminde enönemli faktörler öğretmen ve özel gereksinimli öğrencisidir. Özel eğitim,bedensel ya da zihinsel çeşitli yetersizliklere sahip bireylerin farklı eğitimprogramı ve yöntemlerle tek başlarına hayatta kalmalarını sağlayacakyeterlilikleri kazanmalarını esas alan bir anlayıştır. Kaynaştırma eğitimi iseözel gereksinimli bireylerin yetersizliği olmayan akranlarıyla birlikte eğitimgördüğü ve etkileşim yoluyla beceri edinmelerini sağlayan, destek eğitimhizmetlerinin sağlandığı bir özel eğitim uygulamasıdır. Kaynaştırma eğitimiuygulamalarında başarı ancak süreç içindeki anne-baba, öğretmen, okul yönetimi,rehberlik servisi, normal gelişim gösteren öğrenci ve ailelerinin üzerlerinedüşen sorumluğu üstlenmelerine bağlıdır. Kaynaştırma eğitiminin yalnızcaöğretmen uygulamalarından ibaret olmadığı, bir ekip işi olduğunu unutmamakgerekir. Öğretmen, kuşkusuz ki tutum ve davranışlarıyla kaynaştırma eğitimininbaşarısını arttıran bir etkiye sahiptir. Bu araştırmanın amacı, sınıf öğretmenlerininkaynaştırma eğitimine tabi öğrencilere yönelik tutumlarını etkileyen faktörleribelirlemek ve daha etkili bir kaynaştırma eğitimi yürütülebilmesi için önerilergeliştirebilmektir. Araştırma 2014-2015 eğitim-öğretim yılında İstanbul’daresmî okullarda görevli 40 sınıf öğretmeninin katılımıyla yürütülmüştür. Araştırmadanitel araştırma yöntemlerinden görüşme tekniği kullanılmıştır. Veri toplamaaracı olarak uzman görüşü alınarak araştırmacılar tarafından hazırlanan vesınıf öğretmenlerinin demografik bilgilerini edinmeye yönelik kapalı uçlusorulardan oluşan “Öğretmen Bilgi Formu” ile açık uçlu sorulardan oluşan“Görüşme Soruları” kullanılmıştır. Uygulama, gönüllü olarak araştırmaya katılansınıf öğretmenleri ile yüz yüze görüşülerek gerçekleştirilmiştir. Elde edilenveriler, içerik analizi ile değerlendirilmiştir.Araştırma sonucunda, okulun ve sınıfın fizikîşartlarının, sınıf mevcutlarının, kaynaştırma eğitimi sürecindeki tümilgililerin desteğinin sınıf öğretmeninin iş yükünü hafiflettiği vemotivasyonunu arttırdığı saptanmıştır. Araştırma bulgularına göre, öğrencilerinyetersizlik türleri sınıf öğretmenlerinin kaynaştırma eğitimine yöneliktutumlarını etkilemektedir. Ayrıca, konu hakkında bilgi sahibi olan sınıföğretmenlerinin olmayanlara göre özel gereksinimli öğrencilere daha olumlututumlarla yaklaştıkları saptanmıştır. Kaynaştırma eğitimi için uygun eğitimortamları yaratmak ve öğretmene bu süreçte yalnız olmadığını düşündürecekdestek hizmetleri sağlamak uygulamadaki başarıyı arttıracaktır.In recent years, applications of maintsreaming havebeen gaining great importance in Turkey. The most two important factors in asuccessful mainstreaming education is the teacher and the student with specialneeds.Special education is an understanding that aims to make students with aphysical disability or a mental disability to be able to gain the competenciesfor surviving on his/her own with the help of different educational programmesand methods. Mainstreaming education is a special education application thatchildren with special needs are educated with their peers with no disabilitiesand providing acquisition of skills by interacting and assisted education. Thesuccess of mainstreaming education applications depends only on the cooperationof the parents, teachers, school administration, guidance and psychologicalcounseling service and the students. It has to be taken into consideration thatmainstreaming education is not only about teachers’ efforts but also a groupwork. Beyond any doubt, teachers have an important effect on the success ofmainstreaming education with their attitudes and behaviors.The purpose of this research is to determine thefactors that affect the classroom teacher’s attitudes towards mainstreamedstudents and to offer further suggestions for carrying out a more effectivemainstreaming education. The research was carried out with the participation of40 classroom teachers working in public schools in İstanbul in the academicyear of 2014-2015. In this research, the interview technique was used which isa qualitative research method. As a data collecting tool, with a specialistview, the researcher used “Teacher Information Form” which consists ofclosed-ended questions for acquiring demographic informations of classroomteachers and “Interview Questions” which consists of open-ended questions. Theimplementation was carried out with the volunteering classroom teachers face toface. The acquired data was evaluated with the content analysis.At the result of the research, it was found that thephysical conditions of the school and the classrooms, the number of studentsper class, the people who were responsible and supportive in the process ofmainstreaming education decreased the workload of classroom teachers andincreased their motivation. According to research findings, types of students’disabilities have an affect on the attitudes of classroom teachers towardsmaintsreaming education. In addition, classroom teachers with an understandingand information about the mainstreaming education have more positive attitudestowards the children with special needs.Creating an appropriate educationalenvironment for mainstreaming education and providing supportive services formaking teachers feel not alone in this process may affect mainstreamingapplications positively

Pulmonary Involvement of Diffuse Large B-cell Lymphoma with Cavitary Lesions

Abstract Diffuse large B-cell lymphoma (DLBCL) is the most common type of extranodal lymphoma. Typically disease occurs fastly growing nodal or extranodal masses with systemic symptoms. Pulmonary involvement may also occur in DLBCL. Here we present a DLBCL with cavitary lesions in the lung. A 59-year-old male was diagnosed with DLBCL through an endoscopic gastric biopsy that was performed 1.5 years ago. After six course of R-CHOP chemotherapy, the relaps of disease was confirmed with mediastinoscopy. Despite two courses of RICE chemotherapy and one course of R-BAB therapies, the patient was admitted to the intensive care unit with shortness of breath and tachypnea. Thorax computed tomography showed a mass lesion that enclosed and narrowed the right major bronchus and multiple lesions with cavitation. The infections were excluded with bronchoscopy. The patient received pulse steroid therapy, radiotherapy and three courses of Hyper-CVAD chemotherapy. In the control thorax CT, cavitary lesions got smaller, respiratory insufficiency of patient improved. When pulmonary cavitary lesions are observed in patients under follow-up with the diagnosis of lymphoma, the pulmonary involvement of lymphoma should also be considered in addition to the infectious agents

Preseptal and Orbital Cellulitis in Childhood: The Experience of Ankara Training and Research Hospital

Aim:Evaluation of the etiology, clinical and laboratory findings, treatment and complications of preseptal and orbital cellulitis in patients and to show that these complications can be prevented with early diagnosis and effective treatment.Materials and Methods:Thirty-eight patients with orbital and preseptal cellulitis who had been admitted to Ankara Training and Research Hospital, Clinic of Paediatric between September 2015 and February 2017 were retrospectively studied.Results:Thirty-five patients (92.1%) were diagnosed with preseptal cellulitis and 3 patients (7.9%) were diagnosed with orbital cellulitis. The mean age at diagnosis of the patients [24 girls (63.2%) and 14 boys (36.8%)] was 4.01±3.72 years. The most frequent etiologic factor was conjunctivitis (28.9%). Twenty-five patients (65.7%) were treated with intravenous ampicillin-sulbactam alone as the first treatment. No patient underwent surgery. All patients recovered completely without any eye illnesses and no complications were observed.Conclusion:Orbital infections can be healed through early diagnosis and effective antibiotic therapy in childhood and ampicillin-sulbactam therapy alone should be preferred over combination therapy due to its high effectiveness and relatively low side effects

Clinical course of psoriasis patients that discontinued biologics during the COVID-19 pandemic

BackgroundSince psoriasis is a chronic disease, it is not recommended to discontinue the treatment agents used. However, in real life, the treatment of psoriasis patients may be interrupted for various reasons. During the pandemic period, the treatment of many patients was also interrupted. ObjectivesTo evaluate relapse and clinical worsening in psoriasis patients whose biological therapy was interrupted during the pandemic and reveal associated factors. MethodsThe study included patients aged >= 18 years, who were followed up with moderate and severe chronic psoriasis controlled by the last biological agent [Psoriasis Area Severity Index (PASI) 75 response achieved] but had to discontinue their treatment during the pandemic. The patients' demographic and clinical characteristics, clinical course after the discontinuation of these agents, presence of clinical worsening, and relapse were evaluated. Risk factors were analyzed with the logistic regression analysis. ResultsThe study included 169 patients, with a mean age of 47.3 +/- 14.5 (18-87) years. The mean biologics-free time was 18.2 +/- 12.3 (2-56) weeks. Clinical worsening was detected in 41.4% and relapse in 48.5% of the patients. The significant risk factors for clinical worsening and relapse in both univariate and multivariate analyses were alcohol use during the biologics-free period, total time off biologics, and the presence of an additional triggering factor. The use of secukinumab and ustekinumab was found to be a protective factor against clinical worsening in multivariate analyses. ConclusionAs the biologics-free period is prolonged, the likelihood of clinical worsening and relapse increases, therefore, we do not recommend discontinuing biological agents

COVID-19 in pediatric nephrology centers in Turkey

Background/aim: There is limited data on COVID-19 disease in children with kidney disease. We aimed to investigate the characteristics and prognosis of COVID-19 in pediatric nephrology patients in Turkey. Materials and methods: This was a national, multicenter, retrospective cohort study based on an online survey evaluating the data between 11th March 2020 and 11th March 2021 as an initial step of a detailed pediatric nephrology COVID-19 registry. Results: Two hundred and three patients (89 girls and 114 boys) were diagnosed with COVID-19. One-third of these patients (36.9%) were between 10–15 years old. Half of the patients were on kidney replacement therapy: kidney transplant (KTx) recipients (n = 56, 27.5%), patients receiving chronic hemodialysis (n = 33, 16.3%) and those on peritoneal dialysis (PD) (n = 18, 8.9%). Fifty-four (26.6%) children were asymptomatic. Eighty-two (40.3%) patients were hospitalized and 23 (28%) needed intensive care unit admission. Fifty-five percent of the patients were not treated, while the remaining was given favipiravir (20.7%), steroid (16.3%), and hydroxychloroquine (11.3%). Acute kidney injury developed in 19.5% of hospitalized patients. Five (2.4%) had MIS-C. Eighty-three percent of the patients were discharged without any apparent sequelae, while 7 (3.4%) died. One hundred and eight health care staff were infected during the study period. Conclusion: COVID-19 was most commonly seen in patients who underwent KTx and received HD. The combined immunosuppressive therapy and frequent exposure to the hospital setting may increase these patients’ susceptibility. Staff infections before vaccination era were alarming, various precautions should be taken for infection control, particularly optimal vaccination coverage

Evaluation of patients with fibrotic interstitial lung disease: Preliminary results from the Turk-UIP study

OBJECTIVE: Differential diagnosis of idiopathic pulmonary fibrosis (IPF) is important among fibrotic interstitial lung diseases (ILD). This study aimed to evaluate the rate of IPF in patients with fibrotic ILD and to determine the clinical-laboratory features of patients with and without IPF that would provide the differential diagnosis of IPF. MATERIAL AND METHODS: The study included the patients with the usual interstitial pneumonia (UIP) pattern or possible UIP pattern on thorax high-resolution computed tomography, and/or UIP pattern, probable UIP or possible UIP pattern at lung biopsy according to the 2011 ATS/ERSARS/ALAT guidelines. Demographics and clinical and radiological data of the patients were recorded. All data recorded by researchers was evaluated by radiology and the clinical decision board. RESULTS: A total of 336 patients (253 men, 83 women, age 65.8 +/- 9.0 years) were evaluated. Of the patients with sufficient data for diag-nosis (n=300), the diagnosis was IPF in 121 (40.3%), unclassified idiopathic interstitial pneumonia in 50 (16.7%), combined pulmonary fibrosis and emphysema (CPFE) in 40 (13.3%), and lung involvement of connective tissue disease (CTD) in 16 (5.3%). When 29 patients with definite IPF features were added to the patients with CPFE, the total number of IPF patients reached 150 (50%). Rate of male sex (p<0.001), smoking history (p<0.001), and the presence of clubbing (p=0.001) were significantly high in patients with IPE None of the women <50 years and none of the men <50 years of age without a smoking history were diagnosed with IPE Presence of at least 1 of the symptoms suggestive of CTD, erythrocyte sedimentation rate (ESR), and antinuclear antibody (FANA) positivity rates were significantly higher in the non-IPF group (p<0.001, p=0.029, p=0.009, respectively). CONCLUSION: The rate of IPF among patients with fibrotic ILD was 50%. In the differential diagnosis of IPF, sex, smoking habits, and the presence of clubbing are important. The presence of symptoms related to CTD, ESR elevation, and EANA positivity reduce the likelihood of IPF

Characterization of greater middle eastern genetic variation for enhanced disease gene discovery

The Greater Middle East (GME) has been a central hub of human migration and population admixture. The tradition of consanguinity, variably practiced in the Persian Gulf region, North Africa, and Central Asia1-3, has resulted in an elevated burden of recessive disease4. Here we generated a whole-exome GME variome from 1,111 unrelated subjects. We detected substantial diversity and admixture in continental and subregional populations, corresponding to several ancient founder populations with little evidence of bottlenecks. Measured consanguinity rates were an order of magnitude above those in other sampled populations, and the GME population exhibited an increased burden of runs of homozygosity (ROHs) but showed no evidence for reduced burden of deleterious variation due to classically theorized ‘genetic purging’. Applying this database to unsolved recessive conditions in the GME population reduced the number of potential disease-causing variants by four- to sevenfold. These results show variegated genetic architecture in GME populations and support future human genetic discoveries in Mendelian and population genetics

Diagnosis of comorbid migraine without aura in patients with idiopathic/genetic epilepsy based on the gray zone approach to the International Classification of Headache Disorders 3 criteria

BackgroundMigraine without aura (MwoA) is a very frequent and remarkable comorbidity in patients with idiopathic/genetic epilepsy (I/GE). Frequently in clinical practice, diagnosis of MwoA may be challenging despite the guidance of current diagnostic criteria of the International Classification of Headache Disorders 3 (ICHD-3). In this study, we aimed to disclose the diagnostic gaps in the diagnosis of comorbid MwoA, using a zone concept, in patients with I/GEs with headaches who were diagnosed by an experienced headache expert.MethodsIn this multicenter study including 809 consecutive patients with a diagnosis of I/GE with or without headache, 163 patients who were diagnosed by an experienced headache expert as having a comorbid MwoA were reevaluated. Eligible patients were divided into three subgroups, namely, full diagnosis, zone I, and zone II according to their status of fulfilling the ICHD-3 criteria. A Classification and Regression Tree (CART) analysis was performed to bring out the meaningful predictors when evaluating patients with I/GEs for MwoA comorbidity, using the variables that were significant in the univariate analysis.ResultsLonger headache duration (&lt;4 h) followed by throbbing pain, higher visual analog scale (VAS) scores, increase of pain by physical activity, nausea/vomiting, and photophobia and/or phonophobia are the main distinguishing clinical characteristics of comorbid MwoA in patients with I/GE, for being classified in the full diagnosis group. Despite being not a part of the main ICHD-3 criteria, the presence of associated symptoms mainly osmophobia and also vertigo/dizziness had the distinguishing capability of being classified into zone subgroups. The most common epilepsy syndromes fulfilling full diagnosis criteria (n = 62) in the CART analysis were 48.39% Juvenile myoclonic epilepsy followed by 25.81% epilepsy with generalized tonic-clonic seizures alone.ConclusionLonger headache duration, throbbing pain, increase of pain by physical activity, photophobia and/or phonophobia, presence of vertigo/dizziness, osmophobia, and higher VAS scores are the main supportive associated factors when applying the ICHD-3 criteria for the comorbid MwoA diagnosis in patients with I/GEs. Evaluating these characteristics could be helpful to close the diagnostic gaps in everyday clinical practice and fasten the diagnostic process of comorbid MwoA in patients with I/GEs