Simulation of epoxicomposites structures optical characteristics with operator transformations parameters

Розглянуто науково-практичну проблему створення композитних матеріалів і покриттів на їх основі з підвищеними експлуатаційними характеристиками шляхом дослідження структур зон міжфазної взаємодії в процесі тверднення епоксикомпозитів. Встановлено закономірності кінетики формування зовнішніх поверхневих шарів як прояву таких зон залежно від умісту, дисперсності й фізико-хімічної природи введеного у зв’язувач наповнювача та видано рекомендації щодо прогнозованого регулювання властивостями cформованих матеріалів. Обгрутовано вплив структурних характеристик і геометричних параметрів зовнішніх поверхневих шарів у матриці навколо частинок наповнювача на фізико-механічні характеристики композитного матеріалу.The theoretical and practical problem of composite materials and coatings creating with improved performance by studying the band structure of the interphase interactions during the curing epoxycomposites was considered. There were established the regularities of formation cinetics of the outer surface layers, as a manifestation of such zones. They depend on the content, dispersion and physico- chemical nature of the introduction in the filler and the type of recommendations for management of the predicted properties of generated materials. There was investigated and substantiated the influence of structural characteristics and geometric parameters of the outer surface layers of the matrix around the filler particles and fibers on the dynamics of physical and mechanical char-acteristics of cross-linking of the composite material. A mathematical model of resource in the process of curing epoxycomposites based was builed on the methodology defined boundaries and visualization of spatial clusters of external potentials of the surface layers of dispersed filler. It made the possibility to assess the characteristics of the main stages of the dynamics around dispersed particles microstructures in the volume of the filler matrix composite. It has been hypothesized about the decisive influence of the areas geometric parameters of interfacial interaction on changes in physical and mechanical properties of the filled epoxy composites was . This approach is based on well-developed views, including academician Lipatov Y. S., influence of the solid surface on the kinetics of the formation, morphology, intra - and intermolecular bonds, on the topology of the nets, etc. and, in the end, on the final properties of the polymer matrix. The results of these studies will be used in the development of technology of formation materials and coatings based on them

Simulation of epoxicomposites structures optical characteristics with operator transformations parameters

Розглянуто науково-практичну проблему створення композитних матеріалів і покриттів на їх основі з підвищеними експлуатаційними характеристиками шляхом дослідження структур зон міжфазної взаємодії в процесі тверднення епоксикомпозитів. Встановлено закономірності кінетики формування зовнішніх поверхневих шарів як прояву таких зон залежно від умісту, дисперсності й фізико-хімічної природи введеного у зв’язувач наповнювача та видано рекомендації щодо прогнозованого регулювання властивостями cформованих матеріалів. Обгрутовано вплив структурних характеристик і геометричних параметрів зовнішніх поверхневих шарів у матриці навколо частинок наповнювача на фізико-механічні характеристики композитного матеріалу.The theoretical and practical problem of composite materials and coatings creating with improved performance by studying the band structure of the interphase interactions during the curing epoxycomposites was considered. There were established the regularities of formation cinetics of the outer surface layers, as a manifestation of such zones. They depend on the content, dispersion and physico- chemical nature of the introduction in the filler and the type of recommendations for management of the predicted properties of generated materials. There was investigated and substantiated the influence of structural characteristics and geometric parameters of the outer surface layers of the matrix around the filler particles and fibers on the dynamics of physical and mechanical char-acteristics of cross-linking of the composite material. A mathematical model of resource in the process of curing epoxycomposites based was builed on the methodology defined boundaries and visualization of spatial clusters of external potentials of the surface layers of dispersed filler. It made the possibility to assess the characteristics of the main stages of the dynamics around dispersed particles microstructures in the volume of the filler matrix composite. It has been hypothesized about the decisive influence of the areas geometric parameters of interfacial interaction on changes in physical and mechanical properties of the filled epoxy composites was . This approach is based on well-developed views, including academician Lipatov Y. S., influence of the solid surface on the kinetics of the formation, morphology, intra - and intermolecular bonds, on the topology of the nets, etc. and, in the end, on the final properties of the polymer matrix. The results of these studies will be used in the development of technology of formation materials and coatings based on them

Simple Viscous Flows: from Boundary Layers to the Renormalization Group

The seemingly simple problem of determining the drag on a body moving through a very viscous fluid has, for over 150 years, been a source of theoretical confusion, mathematical paradoxes, and experimental artifacts, primarily arising from the complex boundary layer structure of the flow near the body and at infinity. We review the extensive experimental and theoretical literature on this problem, with special emphasis on the logical relationship between different approaches. The survey begins with the developments of matched asymptotic expansions, and concludes with a discussion of perturbative renormalization group techniques, adapted from quantum field theory to differential equations. The renormalization group calculations lead to a new prediction for the drag coefficient, one which can both reproduce and surpass the results of matched asymptotics

Применение метформина – целевая метаболическая терапия в онкологии

It is well known that metformin is widely used for the treatment of type II diabetes mellitus. However, in numerous epidemiological studies it was shown that patients taking metformin were less likely to have cancer of different localization and had better survival prognosis. Many researchers consider metformin to be a targeted metabolic drug that has many goals: it acts on mitochondria, affects intracellular signaling, blocks channels, inhibits the formation of endothelial and platelet growth factors, reduces the level of vitamins involved in the synthesis of nucleotides and amino acids, etc. It has also been established that metformin belongs to the group of “metabostemness” drugs, that is, it acts on cancer stem cells, blocking their division. We conducted a survey study that highlights the most important mechanisms and fields of application of metformin. The study of the use of this drug in oncology will make it possible to understand the pathogenetic targets of metabolic therapy and the prevention of cancer. Общеизвестно широкое применение метформина для лечения сахарного диабета II типа. Однако в многочисленных эпидемиологических исследованиях было показано, что больные, принимавшие метформин, реже болели раком различной локализации и имели лучший прогноз по выживаемости. Многие исследователи считают метформин таргетным метаболическим препаратом, который имеет множество целей: действует на митохондрии, влияет на внутриклеточный сигналинг, блокирует каналы, тормозит образование эндотелиального и тромбоцитарного факторов роста, снижает уровень витаминов, вовлеченных в синтез нуклеотидов и аминокислот и пр. Также установлено, что метформин относится к группе «метабостемных» препаратов, то есть действует на раковые стволовые клетки, блокируя их деление. Нами проведено обзорное исследование, которое освещает важнейшие механизмы и области применения метформина. Изучение применения данного препарата в онкологии позволит понять патогенетические мишени метаболической терапии и профилактики онкопатологий.

Исследование алгоритмов адаптации для обработки гидроакустических сигналов

Adaptive algorithms for processing signals of antenna arrays in real-time with linear constraints are considered for hydroacoustic tasks. The analysis results of these algorithms are provided and their characteristics are given. Recommendations for using the algorithms in various conditions are given.Рассмотрены адаптивные алгоритмы обработки сигналов антенных решеток в режиме реального времени с линейными ограничениями в приложении к задачам гидроакустики. Приведены результаты анализа указанных алгоритмов и их сравнительные характеристики. Даны рекомендации по использованию алгоритмов

A separation of electrons and protons in the GAMMA-400 gamma-ray telescope

The GAMMA-400 gamma-ray telescope is intended to measure the fluxes of gamma rays and cosmic-ray electrons and positrons in the energy range from 100 MeV to several TeV. Such measurements concern with the following scientific goals: search for signatures of dark matter, investigation of gamma-ray point and extended sources, studies of the energy spectra of Galactic and extragalactic diffuse emission, studies of gamma-ray bursts and gamma-ray emission from the active Sun, as well as high-precision measurements of spectra of high-energy electrons and positrons, protons, and nuclei up to the knee. The main components of cosmic rays are protons and helium nuclei, whereas the part of lepton component in the total flux is ~10E-3 for high energies. In present paper, the capability of the GAMMA-400 gamma-ray telescope to distinguish electrons and positrons from protons in cosmic rays is investigated. The individual contribution to the proton rejection is studied for each detector system of the GAMMA-400 gamma-ray telescope. Using combined information from all detector systems allow us to provide the proton rejection from electrons with a factor of ~4x10E5 for vertical incident particles and ~3x10E5 for particles with initial inclination of 30 degrees. The calculations were performed for the electron energy range from 50 GeV to 1 TeV.Comment: 19 pages, 10 figures, submitted to Advances and Space Researc