209 research outputs found
Decreasing physical and verbal aggression in a brain injured nursing home resident
Following a traumatic brain injury, patients often suffer a series of psychological and psychiatric sequalae. This study presents the case of Mr. K, a 52-year-old brain-injured nursing home resident who exhibited problematic physical aggression and verbal abuse toward staff and residents. His problem behaviors were intertwined with an ethical issue involving a heterosexual relationship with another resident who also was brain injured. Following a functional assessment of antecedents and consequences, a differential reinforcement of other behavior (DRO) schedule was implemented. Specifically, the resident was rewarded with short-term and long-term reinforcers following periods of time during which behaviors other than the target behavior were emitted. Although the behavior plan was successful, it resulted in a more noticeable decrease in physically aggressive behaviors than verbally abusive behaviors. Implications include increasing awareness of use of behavior plans in nursing homes and of ethical and behavioral issues associated with sexuality among nursing home residents
The effect of bacterial lipopolysaccharide on gastric emptying in rats suffering from moderate renal insufficiency
QUBIC: The QU Bolometric Interferometer for Cosmology
One of the major challenges of modern cosmology is the detection of B-mode
polarization anisotropies in the CMB. These originate from tensor fluctuations
of the metric produced during the inflationary phase. Their detection would
therefore constitute a major step towards understanding the primordial
Universe. The expected level of these anisotropies is however so small that it
requires a new generation of instruments with high sensitivity and extremely
good control of systematic effects. We propose the QUBIC instrument based on
the novel concept of bolometric interferometry, bringing together the
sensitivity advantages of bolometric detectors with the systematics effects
advantages of interferometry. Methods: The instrument will directly observe the
sky through an array of entry horns whose signals will be combined together
using an optical combiner. The whole set-up is located inside a cryostat.
Polarization modulation will be achieved using a rotating half-wave plate and
interference fringes will be imaged on two focal planes (separated by a
polarizing grid) tiled with bolometers. We show that QUBIC can be considered as
a synthetic imager, exactly similar to a usual imager but with a synthesized
beam formed by the array of entry horns. Scanning the sky provides an
additional modulation of the signal and improve the sky coverage shape. The
usual techniques of map-making and power spectrum estimation can then be
applied. We show that the sensitivity of such an instrument is comparable with
that of an imager with the same number of horns. We anticipate a low level of
beam-related systematics thanks to the fact that the synthesized beam is
determined by the location of the primary horns. Other systematics should be
under good control thanks to an autocalibration technique, specific to our
concept, that will permit the accurate determination of most of the systematics
parameters.Comment: 12 pages, 10 figures, submitted to Astronomy and Astrophysic
Effect of chloride dialysate concentration on metabolic acidosis in aintenance hemodialysis patients
Strategic positioning:an integrated decision process for manufacturers
Purpose – This paper describes research that has sought to create a formal and rational process that guides manufacturers through the strategic positioning decision. Design/methodology/approach – The methodology is based on a series of case studies to develop and test the decision process. Findings – A decision process that leads the practitioner through an analytical process to decide which manufacturing activities they should carryout themselves. Practical implications – Strategic positioning is concerned with choosing those production related activities that an organisations should carry out internally, and those that should be external and under the ownership and control of suppliers, partners, distributors and customers. Originality/value – This concept extends traditional decision paradigms, such as those associated with “make versus buy” and “outsourcing”, by looking at the interactions between manufacturing operations and the wider supply chain networks associated with the organisation
Human Immunodeficiency Virus and Cardiac End-Organ Damage in Women: Findings From an Echocardiographic Study Across the United States
BACKGROUND: People with human immunodeficiency virus (HIV) have been reported to have increased risk of clinical and subclinical cardiovascular disease. Existing studies have focused on men and often have been uncontrolled or lacked adequate HIV-negative comparators. METHODS: We performed echocardiography in the Women's Interagency HIV Study to investigate associations of HIV and HIV-specific factors with cardiac phenotypes, including left ventricular systolic dysfunction (LVSD), isolated LV diastolic dysfunction (LVDD), left atrial enlargement (LAE), LV hypertrophy (LVH), and increased tricuspid regurgitation velocity (TRV). RESULTS: Of 1654 participants (age 51 ± 9 years), 70% had HIV. Sixty-three (5.4%) women with HIV (WWH) had LVSD; 71 (6.5%) had isolated LVDD. Compared with women without HIV (WWOH), WWH had a near-significantly increased risk of LVSD (adjusted relative risk = 1.69; 95% confidence interval = 1.00 to 2.86; P = .051). No significant association was noted for HIV seropositivity with other phenotypes, but there was a risk gradient for decreasing CD4+ count among WWH that approached or reached significance for isolated LVDD, LAE, and LVH. WWH with CD4+ count <200 cells/mm3 had significantly higher prevalence of LAE, LVH, and high TRV than WWOH. There were no consistent associations for viral suppression or antiretroviral drug exposure. CONCLUSIONS: This study suggests that WWH have a higher risk of LVSD compared with sociodemographically similar WWOH, but their risk for isolated LVDD, LAE, LVH, and high TRV is increased only with reduced CD4+ count. Although these findings warrant replication, they support the importance of cardiovascular risk-factor and HIV-disease control for heart disease prevention in this population
QUBIC: The QU Bolometric Interferometer for Cosmology
Context. One of the major challenges of modern cosmology is the detection of B-mode polarization anisotropies in the Cosmic
Microwave Background. These originate from tensor fluctuations of the metric produced during the inflationary phase. Their detection
would therefore constitute a major step towards understanding the primordial Universe. The expected level of these anisotropies is
however so small that it requires a new generation of instruments with high sensitivity and extremely good control of systematic
eects.
Aims. We propose the QUBIC instrument based on the novel concept of bolometric interferometry, bringing together the sensitivity
advantages of bolometric detectors with the systematics eects advantages of interferometry.
Methods. The instrument will directly observe the sky through an array of entry horns whose signals will be combined together
using an optical combiner. The whole set-up is located inside a cryostat. Polarization modulation will be achieved using a rotating
half-wave plate and the images of the interference fringes will be formed on two focal planes (separated by a polarizing grid) tiled
with bolometers.
Results.We show that QUBIC can be considered as a synthetic imager, exactly similar to a usual imager but with a synthesized beam
formed by the array of entry horns. Scanning the sky provides an additional modulation of the signal and improve the sky coverage
shape. The usual techniques of map-making and power spectrum estimation can then be applied. We show that the sensitivity of
such an instrument is comparable with that of an imager with the same number of horns. We anticipate a low level of beam-related
systematics thanks to the fact that the synthesized beam is determined by the location of the primary horns. Other systematics should
be under good control thanks to an autocalibration technique, specific to our concept, that will permit the accurate determination of
most of the systematics parameters
Team dynamics in emergency surgery teams: results from a first international survey
Background: Emergency surgery represents a unique context. Trauma teams are often multidisciplinary and need to operate under extreme stress and time constraints, sometimes with no awareness of the trauma\u2019s causes or the patient\u2019s personal and clinical information. In this perspective, the dynamics of how trauma teams function is fundamental to ensuring the best performance and outcomes. Methods: An online survey was conducted among the World Society of Emergency Surgery members in early 2021. 402 fully filled questionnaires on the topics of knowledge translation dynamics and tools, non-technical skills, and difficulties in teamwork were collected. Data were analyzed using the software R, and reported following the Checklist for Reporting Results of Internet E-Surveys (CHERRIES). Results: Findings highlight how several surgeons are still unsure about the meaning and potential of knowledge translation and its mechanisms. Tools like training, clinical guidelines, and non-technical skills are recognized and used in clinical practice. Others, like patients\u2019 and stakeholders\u2019 engagement, are hardly implemented, despite their increasing importance in the modern healthcare scenario. Several difficulties in working as a team are described, including the lack of time, communication, training, trust, and ego. Discussion: Scientific societies should take the lead in offering training and support about the abovementioned topics. Dedicated educational initiatives, practical cases and experiences, workshops and symposia may allow mitigating the difficulties highlighted by the survey\u2019s participants, boosting the performance of emergency teams. Additional investigation of the survey results and its characteristics may lead to more further specific suggestions and potential solutions
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