5 research outputs found
E-government systems quality in Kenya: possibility on synergy
Paper presented at ICT conference of 2009.Paper presented at Strathmore ICT Conference, 200
Improving the management of hypertension and diabetes: An implementation evaluation of an electronic medical record system in Nairobi County, Kenya
Site readiness assessment preceding the implementation of a HIV care and treatment electronic medical record system in Kenya
Comparative genomics of the neglected human malaria parasite Plasmodium vivax
The human malaria parasite Plasmodium vivax is responsible for 25-40% of the ∼515 million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe and incapacitating clinical symptoms and often causes relapses months after a primary infection has cleared. Despite its importance as a major human pathogen, P. vivax is little studied because it cannot be propagated continuously in the laboratory except in non-human primates. We sequenced the genome of P. vivax to shed light on its distinctive biological features, and as a means to drive development of new drugs and vaccines. Here we describe the synteny and isochore structure of P. vivax chromosomes, and show that the parasite resembles other malaria parasites in gene content and metabolic potential, but possesses novel gene families and potential alternative invasion pathways not recognized previously. Completion of the P. vivax genome provides the scientific community with a valuable resource that can be used to advance investigation into this neglected species