10 research outputs found

    Reabilitação oral com prótese imediata: relato de caso clínico/ Oral rehabilitation with immediate prosthesis: case report

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    A prótese imediata consiste num aparelho reabilitador e uma alternativa viável para a reabilitação oral com a intenção de recuperar a condição de saúde, bem-estar e autoestima da paciente. Assim, este tipo de tratamento proporciona preservação da dimensão vertical de oclusão, evitando a degradação dos músculos da face. O objetivo deste relato de caso clínico foi apresentar o planejamento da reabilitação de uma paciente, por meio de prótese parcial imediata superior e inferior. Após anamnese, exame físico e avaliação radiográfica, providenciou-se tratamento cirúrgico-protético, que consistiu de planejamento e confecção prévia das próteses dentárias parciais, exodontia dos elementos dentários comprometidos e imediata instalação das próteses. A paciente foi submetida a controles posteriores para acompanhamento e ajustes. Conclui-se que as próteses imediatas representam um procedimento clínico com características definidas, vantajosas e eficazes para os pacientes que perderão dentes de forma total ou parcial, sendo necessário seguir os preceitos já estabelecidos para obter os melhores resultados

    Prevalence and influence of overweight and obesity on clinical and epidemiological profile of breast cancer patients in the North of Mato Grosso, Brazil: a retrospective cross-sectional study

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    Obesity is one of the main preventable risk factors in post-menopausal breast cancer. This retrospective cross-sectional study aimed to demonstrate the clinical and epidemiological profile of breast cancer patients diagnosed in the period from 2013 to 2018 in the North of Mato Grosso, Brazil and to verify the prevalence and influence of overweight and obesity in these patients. Data were collected from patient’s medical records who were diagnosed with breast carcinoma in the Department of Oncology of Santo Antônio’s Hospital, in Sinop-MT. 196 patients were included. 99.5% were women. The majority were married, ≥50 years old (57.7%) and overweight or obese. In the overweight and obesity group the percentage of patients with invasive breast carcinoma were significantly higher when compared with eutrophic group (p=0.03). In all groups the profile of estrogen and progesterone receptors positive and HER-2 negative were more prevalent, however, the frequency of triple negative profile was higher in the overweight (7.1%) and obesity (6.3%) group when compared with control (4.3%) group, as well as the presence of hypertension and diabetes. In conclusion, it was observed a high prevalence of overweight and obesity in breast cancer patients, which contributed to modify the histological type of breast cancer (high prevalence of invasive and lobular carcinomas), increase the frequency of patients in stages 3 and 4, the percentage of triple negative profile and the frequency of other comorbidities, as hypertension and diabetes. Furthermore, metformin, an antidiabetic drug, seems to be contributing to reduce tumor development and improve the clinical profile and prognosis in diabetic breast cancer patients

    Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

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    Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

    Seed and seedling morphology and in vitro crop of rupestric fields Drosera species

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    Objetivou-se com esse trabalho estudar a influ?ncia da luz e da temperatura na germina??o in vitro e ex vitro de sementes de Drosera latifolia, D. hirtella, D. montana e D. schwackei, caracterizando morfologicamente as sementes e pl?ntulas, al?m de desenvolver um protocolo para germina??o in vitro, desenvolvimento de plantas e criopreserva??o de sementes de D. schwackei. Na caracteriza??o f?sica avaliou-se o peso de mil sementes e o grau de umidade. Para a determina??o das caracter?sticas morfol?gicas foram avaliadas a biometria das sementes e suas caracter?sticas externas. Os testes de germina??o foram conduzidos in vitro e ex vitro, para cada esp?cie, por meio de testes com quatro temperaturas constantes (15?C, 20?C, 25?C e 30?C), bem como presen?a e aus?ncia de luz. Concluiu-se que as quatro esp?cies s?o sens?veis ? luz e os melhores resultados de germina??o foram obtidos nas temperaturas de 20?C e 25?C. Na segunda etapa do trabalho, realizou-se um ensaio de desinfesta??o com as sementes de D. schwackei. Ap?s esse processo, as sementes de D. schwackei foram inoculadas em diferentes concentra??es do meio de cultura MS (1/3, 1/2 e 100%) para a an?lise de germina??o. Uma parte das pl?ntulas obtidas a partir do teste de germina??o foi transferida para um novo meio de cultura, com diferentes concentra??es do meio MS (1/3, 1/2 e 100%) para a indu??o do desenvolvimento. A outra parte das pl?ntulas foi subcultivada em meio MS 1/3 dos sais, com diferentes concentra??es de BAP (0,0; 0,5; 1,0 e 1,5 mg.L-1), visando verificar a capacidade de multiplica??o do explante. Os melhores resultados para a germina??o das sementes, desenvolvimento das pl?ntulas e o cultivo in vitro de D. schwackei, foram obtidos utilizando-se o meio MS1/3 e MS1/2. J? as baixas concentra??es de BAP favoreceram o crescimento das plantas in vitro, apesar destas n?o promoverem brota??es. As pl?ntulas obtidas dos experimentos in vitro foram aclimatizadas e o musgo Sphagnum foi o mais indicado. As sementes de D. schwackei foram armazenadas em criotubos e imersas em botij?o contendo nitrog?nio l?quido e mantidas por 1, 6, 12, 24, 48, 120 horas. A criopreserva??o n?o interferiu no desenvolvimento e na morfologia das plantas em nenhum per?odo de armazenamento.Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (CNPq)Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES)Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais (FAPEMIG)Tese (Doutorado) ? Programa de P?s-Gradua??o em Produ??o Vegetal, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2019.The objective of this work was to study the influence of light and temperature on in vitro and ex vitro germination of seeds of Drosera latifolia, Drosera hirtella, Drosera montana and Drosera schwackei, to characterize seeds and seedlings morphologically, also to develop a protocol for germination in vitro, plant development and cryopreservation of D. schwackei seeds. In the physical characterization were evaluated, one thousand seed weight and moisture content. For the determination of the morphological characteristics the biometrics of the seeds, as well as their external characteristics, were evaluated. Germination tests were conducted in vitro and ex vitro for each species. Four constant temperatures (15?C, 20?C, 25?C and 30?C), presence and absence of light were tested. It was concluded that the four species are light sensitive and the best germination results were obtained at temperatures of 20?C and 25?C. In the second stage of the work, a disinfestation test with D. schwackei seeds was carried out. After disinfestation, D. schwackei seeds were inoculated in different concentrations of MS culture medium (1/3, 1/2 and 100%) for germination analysis. Part of the seedlings obtained from the germination test were transferred to a new culture medium, with different concentrations of the MS medium (1/3, 1/2 and 100%), to induce development. The other part of the seedlings were subcultured in MS medium 1/3 of the salts, with different BAP concentrations (0.0, 0.5, 1.0 and 1.5 mg.L-1), aiming to verify the multiplication capacity from explant. Best results for seed germination, seedling development and in vitro cultivation of D. schwackei were obtained using MS1/3 and MS1/2 medium. Low concentrations of BAP favored plant growth in vitro, although they did not promote sprouts. Seedlings obtained from in vitro experiments were acclimatized and Sphagnum moss was the most suitable. Drosera schwackei seeds were stored in cryotubes and immersed in a canister containing liquid nitrogen and kept for 1, 6, 12, 24, 48, 120 hours. Cryopreservation did not interfere with plant development and morphology in any storage period

    Nutritional characteristics of sorghum hybrids hay (sorghum sudanense x sorghum bicolor)

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    This study evaluated the nutritional characteristics of hay of nineteen hybrids between sorghum and Sudan grass. The experimental design was a randomized block with nineteen treatments and three replications. The chemical characteristics of the respective hays were analyzed 52 days after sowing and 45 and 49 regrowth days. Data were analyzed by analysis of variance, and when the F test was significant, the treatment means were compared by the Scott and Knott test at 5%. Genotypes 1013026 and 1014020 showed similar dry matter content. As for ether extract content, the highest values ranged from 2.20 to 2.66%. Higher values of minerals were observed in hybrids 1013026 and 1011005. In relation to crude protein, higher content values were reported for hybrids 1013021 and 1013020 (14.59 and 15.47% CP). When evaluating the neutral detergent fiber content, lower values varied between 56.05 and 57.07% for hybrids 1013016 and 1011009. Considering the content of acid detergent fiber, values ranged from 32.70 to 35.78%. Values of dry matter digestibility were higher than 50%. All hybrids provide quality hay, however the hybrid 1014019 showed the best nutritional value.

    Resumos concluídos - Saúde Coletiva

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    Resumos concluídos - Saúde Coletiv

    Resumos concluídos - Saúde Coletiva

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    Resumos concluídos - Saúde Coletiv

    NEOTROPICAL CARNIVORES: a data set on carnivore distribution in the Neotropics

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    Mammalian carnivores are considered a key group in maintaining ecological health and can indicate potential ecological integrity in landscapes where they occur. Carnivores also hold high conservation value and their habitat requirements can guide management and conservation plans. The order Carnivora has 84 species from 8 families in the Neotropical region: Canidae; Felidae; Mephitidae; Mustelidae; Otariidae; Phocidae; Procyonidae; and Ursidae. Herein, we include published and unpublished data on native terrestrial Neotropical carnivores (Canidae; Felidae; Mephitidae; Mustelidae; Procyonidae; and Ursidae). NEOTROPICAL CARNIVORES is a publicly available data set that includes 99,605 data entries from 35,511 unique georeferenced coordinates. Detection/non-detection and quantitative data were obtained from 1818 to 2018 by researchers, governmental agencies, non-governmental organizations, and private consultants. Data were collected using several methods including camera trapping, museum collections, roadkill, line transect, and opportunistic records. Literature (peer-reviewed and grey literature) from Portuguese, Spanish and English were incorporated in this compilation. Most of the data set consists of detection data entries (n = 79,343; 79.7%) but also includes non-detection data (n = 20,262; 20.3%). Of those, 43.3% also include count data (n = 43,151). The information available in NEOTROPICAL CARNIVORES will contribute to macroecological, ecological, and conservation questions in multiple spatio-temporal perspectives. As carnivores play key roles in trophic interactions, a better understanding of their distribution and habitat requirements are essential to establish conservation management plans and safeguard the future ecological health of Neotropical ecosystems. Our data paper, combined with other large-scale data sets, has great potential to clarify species distribution and related ecological processes within the Neotropics. There are no copyright restrictions and no restriction for using data from this data paper, as long as the data paper is cited as the source of the information used. We also request that users inform us of how they intend to use the data
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