3,955 research outputs found

    Performance evaluation of CEBus power line communication in the presence of X-10 module signaling

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    A power line of CEBus has great potential towards inexpensive home automation. Both PLBus and X-10 uses [sic] burst of 120KHz signals to transmit bits of information on the power line. However, these two systems are completely incompatible and can conflict with each other. This thesis presents the first performance evaluation of Power Line CEBus communication in the presence of X-10 module signaling. The evaluation included simulation experiments measuring packet delays, message delays, message throughput, channel throughput and the percentage of messages received in error verses [sic] different loads. Network performance has been confirmed to function well in terms of delays and throughputs over the practical range of normalized offered load. Also the percentage of CEBus messages received in error due to a collision with X-10 signals did not exceed 2% in all [sic] our cases

    Human Deoxycytidine Kinase Is a Valuable Biocatalyst for the Synthesis of Nucleotide Analogues

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    Natural ribonucleoside-5’-monophosphates are building blocks for nucleic acids which are used for a number of purposes, including food additives. Their analogues, additionally, are used in pharmaceutical applications. Fludarabine-5´-monophosphate, for example, is effective in treating hematological malignancies. To date, ribonucleoside-5’-monophosphates are mainly produced by chemical synthesis, but the inherent drawbacks of this approach have led to the development of enzymatic synthesis routes. In this study, we evaluated the potential of human deoxycytidine kinase (HsdCK) as suitable biocatalyst for the synthesis of natural and modified ribonucleoside-5’-monophosphates from their corresponding nucleosides. Human dCK was heterologously expressed in E. coli and immobilized onto Nickel-nitrilotriacetic acid (Ni-NTA) superflow. A screening of the substrate spectrum of soluble and immobilized biocatalyst revealed that HsdCK accepts a wide range of natural and modified nucleosides, except for thymidine and uridine derivatives. Upon optimization of the reaction conditions, HsdCK was used for the synthesis of fludarabine-5´-monophosphate using increasing substrate concentrations. While the soluble biocatalyst revealed highest product formation with the lowest substrate concentration of 0.3 mM, the product yield increased with increasing substrate concentrations in the presence of the immobilized HsdCK. Hence, the application of immobilized HsdCK is advantageous upon using high substrate concentration which is relevant in industrial applications.DFG, 392246628, Chemo-enzymatische Synthese von Selen-modifizierten Nukleosiden, Nukleotiden und OligonukleotidenTU Berlin, Open-Access-Mittel - 201

    Diaporamas Parcs Nunavik

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    Efficient Poisson Image Editing

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    Image composition refers to the process of composing two or more images to create a natural output image. It is one of the important techniques in image processing. In this paper, two efficient methods for composing color images are proposed. In the proposed methods, the Poisson equation is solved using image pyramid and divide-and-conquer methods. The proposed methods are more efficient than other existing image composition methods. They reduce the time taken in the composition process while achieving almost identical results using the previous image composition methods. In the proposed methods, the Poisson equation is solved after converting it to a linear system using different methods. The results show that the time for composing color images is decreased using the proposed methods

    A morphological generator for the indexing of Arabic audio

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    This paper presents a novel Arabic morphological generator (AMG) for Modern Standard Arabic (MSA) which is designed and implemented using Prolog. The AMG is used to generate inflected forms of words used for the indexing of Arabic audio. These words are also the relevant terms in the Arab authority system (library information retrieval system) used in this study. The AMG generates inflected Arabic words from the root according to pre-specified morphological features that can be extended as needed. The Arabic word is represented as a feature structure which is handled through unification during the morphological generation process. The inflected forms can then be inserted automatically into a speech recognition grammar which is used to identify these words in an audio sequence or utterance

    Secondary metabolites from Calotropis procera (Aiton)

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    Three new metabolites, 5-hydroxy-3,7-dimethoxyflavone-4′-O-β-glucopyranoside (1), 2β,19-epoxy-3β,14β-dihydroxy-19-methoxy-5α-card-20(22)-enolide (4) and β-anhydroepidigitoxigenin-3β-O-glucopyranoside (5), along with two known compounds, uzarigenine (2) and β-anhydroepidigitoxigenin (3), were isolated from Calotropis procera (Asclepiadaceae). The structure elucidation was accomplished mainly by nuclear magnetic resonance (NMR) spectroscopic and mass spectrometric methods. To examine putative antimicrobial or cytotoxic activities, various bioassays were performed. Uzarigenine (2) demonstrated moderate cytotoxicity

    Modelling multiscale aspects of colorectal cancer

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    Colorectal cancer (CRC) is responsible for nearly half a million deaths annually world-wide [11]. We present a series of mathematical models describing the dynamics of the intestinal epithelium and the kinetics of the molecular pathway most commonly mutated in CRC, the Wnt signalling network. We also discuss how we are coupling such models to build a multiscale model of normal and aberrant guts. This will enable us to combine disparate experimental and clinical data, to investigate interactions between phenomena taking place at different levels of organisation and, eventually, to test the efficacy of new drugs on the system as a whole
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