Effects of Zingiber officinale as Feed Additive on the Common Carp Body Composition

The present study was conducted to evaluate the use of ginger powder in diet of common carp, Cyprinus capio (27±3 gr). Different levels of the plant powder (0, 0.25.0.5, 1 and 2 gr / per 100gr food) were spread on commercial diet. The feed was offered by 8 weeks. Results showed that fish fed experimental diets had no significant difference (P>0.05) in amount of NFE, but have significant difference in protein, lipid, ash, moisture percent and kcal energy from different diet (p<0.05) while in kruskal-wallis test illustrated significant difference in amount of carbohydrate and body fiber (p<0.05). So, the best results in amount of protein, lipid, and energy shown in maximum dosage of ginger powder in carp commercial diet  and low amount of them shown in control group.  There were high amount of carbohydrate and low amount of fiber in control group. There was the lack of fiber in control group and upper level of ash in the third treatment. So, this study presents that; to be improving the body composition of common carp we use the herbal medicine like Ginger powder in their commercial diets

A discount ordering strategy in two-level supply chain: A case study of textile industry

Supplier selection, inventory management and optimal lot sizing has been one of the most important issues in many industries especially in production planning issues associated with texture industry. The proposed model of this paper first introduces an algorithm to choose the best supplier and it determines the optimal lot size using discount strategy. The proposed model of this paper considers different influencing factors such as location, quality of materials, cost, and mutual trust for supplier selection, determines their relative importance weights and then a discounting method is used to determine the ordering lot-size. The preliminary results indicate that the proposed model of this paper can be implemented in texture industry, very efficiently since the ordering discount policy is not sensitive to changes on inventory holding and setup expenditures

Analgesic efficacy of bupivacaine alone versus bupivacaine plus dexmedetomidine in penile block for hypospadias surgery

Introduction: Hypospadias is a common pediatric surgical procedure. Early postoperative pain management is essential to inhibit pain impulses and endocrine responses; leading to decreased mortality and morbidity and lower rate of agitation and faster return to normal functional status. This study evaluates the analgesic efficacy of bupivacaine alone versus bupivacaine plus dexmedetomidine in penile block for hypospadias surgery.Materials and Methods: In this randomized clinical trial, 64 children undergoing hypospadias surgery in a referral center in Tehran, Iran during 2018 were enrolled and randomly assigned to receive either bupivacaine 0.25% alone 0.2 ml/kg or bupivacaine 0.25% 0.2 ml/kg plus dexmedetomidine 0.3 μg/kg. After performing penile block, reversion of anesthesia was carried out and patients were extubated after regaining complete consciousness. Patients were monitored for 24 hours for pain according to FLACC scale and also the analgesia and block duration was determined.Results: Mean analgesia duration was 2.63±0.9 and 2.03±0.5 hours in the combination group and alone group respectively which was significant (P=0.003). The mean duration of block was significantly longer in the combination group (P=0.001).Conclusions: According to the results it may be concluded that addition of dexmedetomidine to bupivacaine in hypospadias surgeries would result in longer analgesia and block duration; without addition of adverse effects

Effects of phosalone plant pesticide on sperm parameters and sexual hormone levels in Wistar rats: An experimental study

Background: Phosalone is an organophosphate insecticide, applied to control of plant pests. This compound has various side effects because it acts as an acetyl cholinesterase enzyme inhibitor. Objective: To investigate the effects of phosalone on the sperm parameters of and levels of sex hormones in adult male rats. Materials and Methods: In this experimental study, 16 adult (8-12 wk) male Wister rates (weighing 220-280 gr) were randomly assigned into 4 groups (n = 4/each). Group 1 (control) received only routine adequate water and food; Group 2, 3, and 4 received different low doses of phosalone (60, 90, and 120 mg/kg respectively). The rats were weighed and anesthetized after 48 days. Sperm parameters including number, motility, and viability as well as sex hormones (such as Luteinizing Hormone, Follicle Stimulating Hormone, and testosterone) were evaluated and compared after removing the epididymis tail. Results: Our results showed that phosalone decreased sperm motility, viability, and number in a dose-dependent manner. The level of FSH and LH was increased, and testosterone was decreased. Also, depending on the dose, phosalone decrease sperm motility and viability (p ≤ 0.001), while the level of FSH and LH was increased and testosterone was decreased (p = 0.861). Conclusion: Phosalone has negative effects on reproductive indices in male rats and can cause serious damage and decrease the number and sperms motility. It can also cause infertility due to changing the concentration of hormones. Key words: Organophosphate, Pesticides, Phosalone, Sperm, Sex hormones

Genome sequences of Beet curly top Iran virus, Oat dwarf virus, Turnip curly top virus, and wheat dwarf virus identified in leafhoppers

Implementation of a vector-enabled metagenomics approach resulted in the identification of various geminiviruses. We identified the genome sequences of Beet curly top Iran virus, Turnip curly top viruses, Oat dwarf viruses, the first from Iran, and Wheat dwarf virus from leafhoppers feeding on beet, parsley, pumpkin, and turnip plants

Effects of Zingiber officinale as Feed Additive on the Common Carp Body Composition

The present study was conducted to evaluate the use of ginger powder in diet of common carp, Cyprinus capio (27±3 gr). Different levels of the plant powder (0, 0.25.0.5, 1 and 2 gr / per 100gr food) were spread on commercial diet. The feed was offered by 8 weeks. Results showed that fish fed experimental diets had no significant difference (P>0.05) in amount of NFE, but have significant difference in protein, lipid, ash, moisture percent and kcal energy from different diet (p<0.05) while in kruskal-wallis test illustrated significant difference in amount of carbohydrate and body fiber (p<0.05). So, the best results in amount of protein, lipid, and energy shown in maximum dosage of ginger powder in carp commercial diet  and low amount of them shown in control group.  There were high amount of carbohydrate and low amount of fiber in control group. There was the lack of fiber in control group and upper level of ash in the third treatment. So, this study presents that; to be improving the body composition of common carp we use the herbal medicine like Ginger powder in their commercial diets

Function of arteries and veins in conditions of simulated cardiac arrest

Introduction: The study examined the behavior of vasculature in conditions of eliminated cardiac function using mathematical modeling. In addition, we addressed the question of whether the stretch-recoil capability of veins, at least in part accounts for the slower response to simulated cardiac arrest. Methods: In the first set of computational experiments, blood flow and pressure patterns in veins and arteries during the first few seconds after cardiac arrest were assessed via a validated multi-scale mathematical model of the whole cardiovascular system, comprising cardiac dynamics, arterial and venous blood flow dynamics, and microcirculation. In the second set of experiments, the effects of stretch-recoil zones of venous vessels with different diameters and velocities on blood velocity and dynamic pressure analyzed using computational fluid dynamics (CFD) modeling. Results: In the first set of experiments, measurement of changes in velocity, dynamic pressure, and fluid flow revealed that the venous system responded to cardiac arrest more slowly compared to the arteries. This disparity might be due to the intrinsic characteristics of the venous system, including stretch-recoil and elastic fiber composition. In the second set of experiments, we attempted to determine the role of the stretch-recoil capability of veins in the slower response to cardiac arrest. During the second set of experiments, we found that this recoil behavior increased dynamic pressure, velocity, and blood flow. The enhancement in dynamic pressure through combining the results from both experiments yielded a 15-40% increase in maximum dynamic pressure due to stretch-recoil, depending on vein diameter under normal conditions. Conclusion: In the situation of cardiac arrest, the vein geometry changes continue, promoting smooth responses of the venous system. Moreover, the importance of such vein behavior in blood displacement may grow as the pressure on the venous side gradually decreases with time. Our experiments suggest that the driving force for venous return is the pressure difference that remains within the venous system after the energy coming from every ventricular systole spent to overcome the resistance created by arterial and capillary systems

Assessment of Moisture Status and Crop Production in Different Climate of Iran

Drought varies with regard to the time of occurrence, duration, intensity, and extent of the area affected from year to year. The objective of this study was therefore to gather and analyze standardized information on Role of Early Warning Systems by FAO56 and UNESCO models for cereals (wheat, barley, corn and rice), leguminous (bean, chickpea, lentil and alfalfa) and industrial crops (soybean, sunflower, canola, sugare beat, potato and cotton) in Iran environmental zones. To gather information on perceived risks and foreseen impacts of climatic factors on crops production, we designed a set of qualitative and quantitative data from agrometeorological and agriculture organizations in 44 stations in Iran (1961-2010). Annual average rainfall (mm.y-1) and ETo (mm.y-1) in stations with very dry climate are 76.56 and 3001.03, respectively, these rates for stations with dry climate are 195.41 mm.y-1 and 2249.44 mm.y-1, for stations with semi dry climate is 343.9 mm.y-1 and 1351.62 mm.y-1, for stations with semi humid climate is 583.8 mm.y-1 and 1153.4 mm.y-1 and for stations with humid climate is 1272.16 mm.y-1 and 949.91 mm.y-1. The maximum and minimum of Annual average rainfall happened in Rasht (1337.5 mm.y-1) and Zabol (57.7 mm.y-1) stations, and the maximum and minimum for Annual average ETo happened in Chabahar (3909.15 mm.y-1) and Anzali harbor (890.6 mm.y-1), respectively. Therefore, 13.63 percent of stations have suitable conditions for crop productions and 86.37 percent are in critical and unsustainable conditions

Comparison of cytotoxicity of Miltefosine and its niosomal form on chick embryo model

© 2024 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/Various drugs have been used for the treatment of leishmaniasis, but they often have adverse effects on the body's organs. In this study, we aimed to explore the effects of one type of drug, Miltefosine (MIL), and its analogue or modifier, liposomal Miltefosine (NMIL), on several fetal organs using both in silico analysis and practical tests on chicken embryos. Our in silico approach involved predicting the affinities of MIL and NMIL to critical proteins involved in leishmaniasis, including Vascular Endothelial Growth Factor A (VEGF-A), the Kinase insert domain receptor (KDR1), and apoptotic-regulator proteins (Bcl-2-associate). We then validated and supported these predictions through in vivo investigations, analyzing gene expression and pathological changes in angiogenesis and apoptotic mediators in MIL- and NMIL-treated chicken embryos. The results showed that NMIL had a more effective action towards VEGF-A and KDR1 in leishmaniasis, making it a better candidate for potential operative treatment during pregnancy than MIL alone. In vivo, studies also showed that chicken embryos under MIL treatment displayed less vascular mass and more degenerative and apoptotic changes than those treated with NMIL. These results suggest that NMIL could be a better treatment option for leishmaniasis during pregnancy.Peer reviewe