About a uni-cervical unicorn uterus case with vaginal septum

The unicorn uterus is a common uterine malformation after septate uteri, accounting for 30 to 50% of cases. We report a case of unicorn uterus with an associated vaginal septum discovered during the obstetrical examination of a consultant surgeon for hemorrhage, and exploration of the uterus revealed a uterus during a cesarean section. Maternal-fetal rescue for placenta previa. The interest of this case is to show the double embryological mechanism involved, unilateral aplasia of the muller ducts and the lack of resorption explaining this vaginal septum

Implications of storing urinary DNA from different populations for molecular analyses.

Molecular diagnosis using urine is established for many sexually transmitted diseases and is increasingly used to diagnose tumours and other infectious diseases. Storage of urine prior to analysis, whether due to home collection or bio-banking, is increasingly advocated yet no best practice has emerged. Here, we examined the stability of DNA in stored urine in two populations over 28 days

Review of Riemannian Distances and Divergences, Applied to SSVEP-based BCI

International audienc

Oral ketamine: A four-years experience in a tumour clinic in Lusaka Zambia

Pain management is an important component in cancer management. The administration of painful injections to children in an oncology clinic can create difficulties. This study was undertaken to determine the role of oral ketamine to modify the response to pain. Between 1996 and 1999,6324 patients attended a tumour clinic in a developing country teaching hospital. Forty eight children required cytotoxic injections on 103 occasions. These children were subdivided into 3 groups according to the year of attendance: 1996,1997 and 1998/8. each group was premeded differently. The first group received ketamine 4.5mg/Kg; the second received ketamine Gmg/Kg and the third had ketamine 6mg/Kg with diazepam O.lmg/Kg. The  esponse to pain in each group was evaluated by using an observer based scoring system. The visual analogue scale was not used. The study showed that oral ketamine is an effective and safe drug for use in a clinic setting. However, its action was not always predictable due to a number of confounding factors. A phenothiazine should be routinely used in these children to enhance the effectiveness of ketamine and to diminish the likelihood of its well-known side effects. Further studies using less costly lower doses of ketamine is recommended. Key words: Oral Ketamine, Premedication and Oncology

Local perceptions of cholera and anticipated vaccine acceptance in Katanga province, Democratic Republic of Congo

ABSTRACT: BACKGROUND: In regions where access to clean water and the provision of a sanitary infrastructure has not been sustainable, cholera continues to pose an important public health burden. Although oral cholera vaccines (OCV) are effective means to complement classical cholera control efforts, still relatively little is known about their acceptability in targeted communities. Clarification of vaccine acceptability prior to the introduction of a new vaccine provides important information for future policy and planning. METHODS: In a cross-sectional study in Katanga province, Democratic Republic of Congo (DRC), local perceptions of cholera and anticipated acceptance of an OCV were investigated. A random sample of 360 unaffected adults from a rural town and a remote fishing island was interviewed in 2010. In-depth interviews with a purposive sample of key informants and focus-group discussions provided contextual information. Socio-cultural determinants of anticipated OCV acceptance were assessed with logistic regression. RESULTS: Most respondents perceived contaminated water (63%) and food (61%) as main causes of cholera. Vaccines (28%), health education (18%) and the provision of clean water (15%) were considered the most effective measures of cholera control. Anticipated acceptance reached 97% if an OCV would be provided for free. Cholera-specific knowledge of hygiene and self-help in form of praying for healing were positively associated with anticipated OCV acceptance if costs of USD 5 were assumed. Conversely, respondents who feared negative social implications of cholera were less likely to anticipate acceptance of OCVs. These fears were especially prominent among respondents who generated their income through fishing. With an increase of assumed costs to USD 10.5, fear of financial constraints was negatively associated as well. CONCLUSIONS: Results suggest a high motivation to use an OCV as long as it seems affordable. The needs of socially marginalized groups such as fishermen may have to be explicitly addressed when preparing for a mass vaccination campaig

A Review of Classification Algorithms for EEG-based Brain-Computer Interfaces: A 10-year Update

International audienceObjective: Most current Electroencephalography (EEG)-based Brain-Computer Interfaces (BCIs) are based on machine learning algorithms. There is a large diversity of classifier types that are used in this field, as described in our 2007 review paper. Now, approximately 10 years after this review publication, many new algorithms have been developed and tested to classify EEG signals in BCIs. The time is therefore ripe for an updated review of EEG classification algorithms for BCIs. Approach: We surveyed the BCI and machine learning literature from 2007 to 2017 to identify the new classification approaches that have been investigated to design BCIs. We synthesize these studies in order to present such algorithms, to report how they were used for BCIs, what were the outcomes, and to identify their pros and cons. Main results: We found that the recently designed classification algorithms for EEG-based BCIs can be divided into four main categories: adaptive classifiers, matrix and tensor classifiers, transfer learning and deep learning, plus a few other miscellaneous classifiers. Among these, adaptive classifiers were demonstrated to be generally superior to static ones, even with unsupervised adaptation. Transfer learning can also prove useful although the benefits of transfer learning remain unpredictable. Riemannian geometry-based methods have reached state-of-the-art performances on multiple BCI problems and deserve to be explored more thoroughly, along with tensor-based methods. Shrinkage linear discriminant analysis and random forests also appear particularly useful for small training samples settings. On the other hand, deep learning methods have not yet shown convincing improvement over state-of-the-art BCI methods. Significance: This paper provides a comprehensive overview of the modern classification algorithms used in EEG-based BCIs, presents the principles of these Review of Classification Algorithms for EEG-based BCI 2 methods and guidelines on when and how to use them. It also identifies a number of challenges to further advance EEG classification in BCI