Scavi e ricerche ad Althiburos (INP e ISMA-CNR)

The Tunisian National Heritage Institute and the Institute for the Studies on Ancient Mediterranean, of the Italian National Research Council, lead by several years archaeological research in el Médéïna (ancient Althiburos). Here we present the main aspects of the Tunisian-Italian cooperation and an assessment of the results achieved so farL’Institut National du Patrimoine e l’Istituto di Studi sul Mediterraneo Antico del Consiglio Nazionale delle Ricerche conducono da vari anni ricerche archeologiche nel sito di el Médéïna, l’antica Althiburos. Qui si presentano gli aspetti principali della cooperazione tunisino-italiana e alcuni dei risultati finora raggiunti.

Nuove ricerche tuniso-italiane al teatro romano di Althiburos

Nuove indagini archeologiche condotte dall'Universit\ue0 di Macerata e dall'institut National du Patrimoine di Tunisi presso il teatro romano di Althiburos (Tunisia)

El projecte de recerca arqueològica a Althiburos i els seus encontorns (El Kef, Tunísia)

El coneixement de la protohistòria del Magrib oriental –entenent com a tal l’edat del bronze i la primera edat del ferro, és a dir, el segon i el primer mil·lennis aC, de la zona que correspon a les actuals Tunísia i Algèria oriental– presenta un veritable buit. Això és evident si es compara amb l’estat de la recerca sobre el mateix període a Europa, i potser encara més amb el coneixement sobre el paleolític i el neolític al nord d’Àfrica. Per al final d’aquest període, les fonts escrites gregues i romanes aporten dades abundants sobre els regnes númides i les seves relacions complexes amb Cartago i, més tard, amb Roma. Si bé existeix documentació arqueològica sobre aquests regnes, el cert és que presenta llacunes molt importants, i que, remuntant en el temps, tenim un desconeixement gairebé absolut sobre aquesta zona des de finals del III mil·lenni aC

Iron age genomic data from Althiburos – Tunisia renew the debate on the origins of African taurine cattle

The Maghreb is a key region for understanding the dynamics of cattle dispersal and admixture with local aurochs following their earliest domestication in the Fertile Crescent more than 10,000 years ago. Here, we present data on autosomal genomes and mitogenomes obtained for four archaeological specimens of Iron Age (∼2,800 cal BP–2,000 cal BP) domestic cattle from the Eastern Maghreb, i.e. Althiburos (El Kef, Tunisia). D-loop sequences were obtained for an additional eight cattle specimens from this site. Maternal lineages were assigned to the elusive R and ubiquitous African-T1 haplogroups found in two and ten Althiburos specimens, respectively. Our results can be explained by post-domestication hybridization of Althiburos cattle with local aurochs. However, we cannot rule out an independent domestication in North Africa considering the shared ancestry of Althiburos cattle with the pre-domestic Moroccan aurochs and present-day African taurine cattle.info:eu-repo/semantics/publishedVersio

The successes and challenges of harmonising juvenile idiopathic arthritis (JIA) datasets to create a large-scale JIA data resource

Background CLUSTER is a UK consortium focussed on precision medicine research in JIA/JIA-Uveitis. As part of this programme, a large-scale JIA data resource was created by harmonizing and pooling existing real-world studies. Here we present challenges and progress towards creation of this unique large JIA dataset. Methods Four real-world studies contributed data; two clinical datasets of JIA patients starting first-line methotrexate (MTX) or tumour necrosis factor inhibitors (TNFi) were created. Variables were selected based on a previously developed core dataset, and encrypted NHS numbers were used to identify children contributing similar data across multiple studies. Results Of 7013 records (from 5435 individuals), 2882 (1304 individuals) represented the same child across studies. The final datasets contain 2899 (MTX) and 2401 (TNFi) unique patients; 1018 are in both datasets. Missingness ranged from 10 to 60% and was not improved through harmonisation. Conclusions Combining data across studies has achieved dataset sizes rarely seen in JIA, invaluable to progressing research. Losing variable specificity and missingness, and their impact on future analyses requires further consideration

Darrers resultats del projecte de recerca tunisianocatalà a la ciutat numidoromana d'Althiburos i els seus encontorns

En altres números de la revista AURIGA hem tingut ocasió de donar notícies sobre els resultats obtinguts en el projecte de recerca tunisianocatalà a la ciutat númida, i després romana, d'Althiburos, a la república de Tunísia. Ens limitarem, doncs, a recordar que l'objectiu dels nostres treballs és recuperar documentació rellevant que permeti plantejar hipòtesis mínimament sòlides sobre els processos de formació i desenvolupament dels estats númides que van tenir lloc durant el primer mil·lenni aC

Description of the rates, trends and surgical burden associated with revision for prosthetic joint infection following primary and revision knee replacements in England and Wales: an analysis of the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man.

To describe the prevalence rates of revision surgery for the treatment of prosthetic joint infection (PJI) for patients undergoing knee replacement, their time trends, the cumulative incidence function of revision for PJI and estimate the burden of PJI at health service level.This article is freely available via Open Access. Click on the Additional Link above to access the full-text via the publisher's site