The effect of the 1,2,3-triazolo[5,1-b][1,3,4]thiadiazines on Solanum lycopersicum L. seed germination

ArticleIn recent years chemical pesticides are being replaced by environmentally friendly and universal means of plant protection that are able to exert a complex effect on the plant (stimulate growth and development, improve metabolic processes, develop resistance to pathogens, etc.). The effect of new synthetic growth regulators of the 1,2,3-triazolo[5,1-b][1,3,4]thiadiazine class and trade phytohormones (6-BAP, GA and TDZ) on the growth processes, growth energy and vitality of tomato seeds, as well as morphological parameters of seedlings was researched in this article. It was revealed that the effect of synthesized compounds on seed vigor and viability of seedlings are superior to commercial phytohormones. In the early stages of germination the seed vigor of tomato seeds treated with the compounds TT1-TT5 were superior to one in treatments with phytohormones and in control experiment. As a result of the experiment, the most viable seedlings were formed into the treatments TT1, TT2 and TT3 (in all studied concentrations). Tomato seedlings treated with 6-BAP and GA at a concentration of 5 mg L -1 produced the worst results

Prospects of application of tubes made of duplex steels of a new generation in the heat exchanging equipment of nuclear power plants

Prospects of using tubes produced by Centravis Production Ukraine JSC of ferritic-austenitic (duplex) steels of a new generation according to the developed innovative technology in the heat exchanging equipment of nuclear power plants (NPP) were scientifically substantiated based on analysis of scientific and technical literature and the results obtained in comprehensive studies. Comparative corrosion studies of the tubes made of austenitic Cr-Ni and Cr-Ni-Mo steels and 02Cr22Ni5NМo3 (UNS S 31803) duplex steel have shown a substantially improved resistance of the latter to intercrystalline, pit and crevice corrosion, corrosion cracking and erosion. Presence of special lowenergy γ-γ, α-α grain boundaries and α-γ interphase boundaries characterized by an increased corrosion resistance and a contribution to the growth of steel durability as a whole was found for the first time in the structure of ferriticaustenitic steels.На основі аналізу науково-технічної літератури і результатів комплексних досліджень науково обґрунтована перспективність застосування труб з феритно-аустенітних (дуплексних) сталей нового покоління, які виготовляє за розробленою інноваційною технологією ПрАТ «Сентравіс Продакшн Юкрейн», у теплообмінному обладнання АЕС. Порівняльні дослідження корозійної тривкості труб з аустенітних CrNi- і Cr-Ni-Mo-сталей і дуплексної сталі 02Х22Н5АМ3 (UNS S 31803) показали значно вищу тривкість останніх проти міжкристалітної, пітінгової, виразкової, щілинної корозій, корозійного розтріскування і ерозії. Вперше встановлено наявність у структурі феритно-аустенітних сталей спеціальних низькоенергетичних границь зерен γ-γ і α-α і міжфазних границь α-γ, які характеризуються підвищеною корозійною тривкістю та сприяють підвищенню корозійної тривкості сталі в цілому.На основании анализа научно-технической литературы и результатов комплексных исследований научно обоснована перспективность использования труб из ферритно-аустенитных (дуплексных) сталей нового поколения, которые изготавливает по разработанной инновационной технологии ЧАО «Сентравис Продакшн Юкрейн», в теплообменном оборудовании АЭС. Сравнительные исследования коррозионной стойкости труб из аустенитных Cr-Ni- и Cr-Ni-Mo-сталей и дуплексной стали 02Х22Н5АМ3 (UNS S 31803) показали значительно более высокую стойкость последних против межкристаллитной, питтинговой, язвенной, щелевой коррозий, коррозионного растрескивания и эрозии. Впервые установлено наличие в структуре ферритно-аустенитных сталей специальных низкоэнергетических границ зерен γ-γ, α-α и межфазных границ α-γ, характеризующихся повышенной коррозионной стойкостью и способствующих повышению стойкости стали в целом

Клиническое значение лазерного конверсионного тестирования в диагностике и лечении хронического эндометрита

In article presents the identified characteristics of spectral characteristics of endometrium in normal and chronic adnexitis. Identifies opportunities and prospects of laser conversion diagnostics monitoring, efficiency treatment and rehabilitation of patients with chronic èndometritom.В статье представлены данные выявленных особенностей спектральных характеристик эндометрия в норме и при хроническом эндометрите. Определены возможности и перспективы использования лазерной конверсионной диагностики в мониторинге эффективности лечения и реабилитации больных хроническим эндометритом

Fungal Planet description sheets : 1182–1283

Novel species of fungi described in this study include those from various countries as follows: Algeria, Phaeoacremonium adelophialidum from Vitis vinifera. Antarctica, Comoclathris antarctica from soil. Australia, Coniochaeta salicifolia as endophyte from healthy leaves of Geijera salicifolia, Eremothecium peggii in fruit of Citrus australis, Microdochium ratticaudae from stem of Sporobolus natalensis, Neocelosporium corymbiae on stems of Corymbia variegata, Phytophthora kelmanii from rhizosphere soil of Ptilotus pyramidatus, Pseudosydowia backhousiae on living leaves of Backhousia citriodora, Pseudosydowia indooroopillyensis, Pseudosydowia louisecottisiae and Pseudosydowia queenslandica on living leaves of Eucalyptus sp. Brazil, Absidia montepascoalis from soil. Chile, Ilyonectria zarorii from soil under Maytenus boaria. Costa Rica, Colletotrichum filicis from an unidentified fern. Croatia, Mollisia endogranulata on deteriorated hardwood. Czech Republic, Arcopilus navicularis from tea bag with fruit tea, Neosetophoma buxi as endophyte from Buxus sempervirens, Xerochrysium bohemicum on surface of biscuits with chocolate glaze and filled with jam. France, Entoloma cyaneobasale on basic to calcareous soil, Fusarium aconidiale from Triticum aestivum, Fusarium juglandicola from buds of Juglans regia. Germany, Tetraploa endophytica as endophyte from Microthlaspi perfoliatum roots. India, Castanediella ambae on leaves of Mangifera indica, Lactifluus kanadii on soil under Castanopsis sp., Penicillium uttarakhandense from soil. Italy, Penicillium ferraniaense from compost. Namibia, Bezerromyces gobabebensis on leaves of unidentified succulent, Cladosporium stipagrostidicola on leaves of Stipagrostis sp., Cymostachys euphorbiae on leaves of Euphorbia sp., Deniquelata hypolithi from hypolith under a rock, Hysterobrevium walvisbayicola on leaves of unidentified tree, Knufia hypolithi and Knufia walvisbayicola from hypolith under a rock, Lapidomyces stipagrostidicola on leaves of Stipagrostis sp., Nothophaeotheca mirabibensis (incl. Nothophaeotheca gen. nov.) on persistent inflorescence remains of Blepharis obmitrata, Paramyrothecium salvadorae on twigs of Salvadora persica, Preussia procaviicola on dung of Procavia sp., Sordaria equicola on zebra dung, Volutella salvadorae on stems of Salvadora persica. Netherlands, Entoloma ammophilum on sandy soil, Entoloma pseudocruentatum on nutrient poor (acid) soil, Entoloma pudens on plant debris, amongst grasses. New Zealand, Amorocoelophoma neoregeliae from leaf spots of Neoregelia sp., Aquilomyces metrosideri and Septoriella callistemonis from stem discolouration and leaf spots of Metrosideros sp., Cadophora neoregeliae from leaf spots of Neoregelia sp., Flexuomyces asteliae (incl. Flexuomyces gen. nov.) and Mollisia asteliae from leaf spots of Astelia chathamica, Ophioceras freycinetiae from leaf spots of Freycinetia banksii, Phaeosphaeria caricis-sectae from leaf spots of Carex secta. Norway, Cuphophyllus flavipesoides on soil in semi-natural grassland, Entoloma coracis on soil in calcareous Pinus and Tilia forests, Entoloma cyaneolilacinum on soil semi-natural grasslands, Inocybe norvegica on gravelly soil. Pakistan, Butyriboletus parachinarensis on soil in association with Quercus baloot. Poland, Hyalodendriella bialowiezensis on debris beneath fallen bark of Norway spruce Picea abies. Russia, Bolbitius sibiricus on а moss covered rotting trunk of Populus tremula, Crepidotus wasseri on debris of Populus tremula, Entoloma isborscanum on soil on calcareous grasslands, Entoloma subcoracis on soil in subalpine grasslands, Hydropus lecythiocystis on rotted wood of Betula pendula, Meruliopsis faginea on fallen dead branches of Fagus orientalis, Metschnikowia taurica from fruits of Ziziphus jujube, Suillus praetermissus on soil, Teunia lichenophila as endophyte from Cladonia rangiferina. Slovakia, Hygrocybe fulgens on mowed grassland, Pleuroflammula pannonica from corticated branches of Quercus sp. South Africa, Acrodontium burrowsianum on leaves of unidentified Poaceae, Castanediella senegaliae on dead pods of Senegalia ataxacantha, Cladophialophora behniae on leaves of Behnia sp., Colletotrichum cliviigenum on leaves of Clivia sp., Diatrype dalbergiae on bark of Dalbergia armata, Falcocladium heteropyxidicola on leaves of Heteropyxis canescens, Lapidomyces aloidendricola as epiphyte on brown stem of Aloidendron dichotomum, Lasionectria sansevieriae and Phaeosphaeriopsis sansevieriae on leaves of Sansevieria hyacinthoides, Lylea dalbergiae on Diatrype dalbergiae on bark of Dalbergia armata, Neochaetothyrina syzygii (incl. Neochaetothyrina gen. nov.) on leaves of Syzygium chordatum, Nothophaeomoniella ekebergiae (incl. Nothophaeomoniella gen. nov.) on leaves of Ekebergia pterophylla, Paracymostachys euphorbiae (incl. Paracymostachys gen. nov.) on leaf litter of Euphorbia ingens, Paramycosphaerella pterocarpi on leaves of Pterocarpus angolensis, Paramycosphaerella syzygii on leaf litter of Syzygium chordatum, Parateichospora phoenicicola (incl. Parateichospora gen. nov.) on leaves of Phoenix reclinata, Seiridium syzygii on twigs of Syzygium chordatum, Setophoma syzygii on leaves of Syzygium sp., Starmerella xylocopis from larval feed of an Afrotropical bee Xylocopa caffra, Teratosphaeria combreti on leaf litter of Combretum kraussii, Teratosphaericola leucadendri on leaves of Leucadendron sp., Toxicocladosporium pterocarpi on pods of Pterocarpus angolensis. Spain, Cortinarius bonachei with Quercus ilex in calcareus soils, Cortinarius brunneovolvatus under Quercus ilex subsp. ballota in calcareous soil, Extremopsis radicicola (incl. Extremopsis gen. nov.) from root-associated soil in a wet heathland, Russula quintanensis on acidic soils, Tubaria vulcanica on volcanic lapilii material, Tuber zambonelliae in calcareus soil. Sweden, Elaphomyces borealis on soil under Pinus sylvestris and Betula pubescens. Tanzania, Curvularia tanzanica on inflorescence of Cyperus aromaticus. Thailand, Simplicillium niveum on Ophiocordyceps camponoti-leonardi on underside of unidentified dicotyledonous leaf. USA, Calonectria californiensis on leaves of Umbellularia californica, Exophiala spartinae from surface sterilised roots of Spartina alterniflora, Neophaeococcomyces oklahomaensis from outside wall of alcohol distillery. Vietnam, Fistulinella aurantioflava on soil. Morphological and culture characteristics are supported by DNA barcodes.http://www.ingentaconnect.com/content/nhn/pimjBiochemistryForestry and Agricultural Biotechnology Institute (FABI)GeneticsMicrobiology and Plant PathologyPlant Production and Soil Scienc

Synthesis and Structure of 1-(1,2,3-Thiadiazolylcarbonyl)-4-(1,2,3-thiadiazolyl)semicarbazide Derivatives

Novel unknown potentially biologically active 1-(1,2,3-thiadizolylcarbonyl)-4-(1,2,3-thiadiazolyl)-semicarbazides were synthesized by reactions of 1,2,3-thiadiazolylcarboxylic acid hydrazides with 1,2,3- thiadizolylcarbonyl azide in high yields. The structure of the synthesized compounds was studied by NMR and IR spectroscopy and X-ray diffraction analysis. © 2018, Pleiades Publishing, Ltd

Laser conversion express diagnostics and high-volume photoactive therapy of endometrial hyperplastic processes

The objective. Assessment of the effectiveness of laser fluorescence conversion spectroscopy and high-volume photo-active (photodynamic and photo-immune) therapy in diagnosis and treatment of endometrial hyperplastic processes (EHP) in infertile women on the programmes of assisted reproductive technologies (ART). Patients and methods. A clinical-laboratory examination and treatment of 68 female patients aged 35-47 (41.15 ± 2.18) years with primary and secondary infertility, CE and various forms of EHP was performed. All women underwent planned routine examination before an IFV programme. The control group consisted of 10 healthy women, who were preparing for ART. Ultrasound examination of the pelvic organs was performed in all patients using colour Doppler mapping with assessment of flow rate curves in vessels of the small pelvis. Also, bacteriological and cytological examinations were performed. The main monitoring method of assessment of the morphofunctional state of the endometrium was laser fluorescence conversion diagnostics of the endometrium. High-volume complex photo-active therapy (PAT) was performed under the control of laser conversion diagnostics (LCD) (fluorescent constituent) on a certified device «EnSpectr M» with the use of chlorophyll-containing preparation for oral use 0.5-3.0 ml daily with preliminary processing by laser radiation with wavelength 0.63 μm in the dose 20-40 J/cm2 for 4-6 wks. Results. Fluorescence of a normal endometrium (proliferative activity) was 6-8 x 107-108 RFU. The aerobicity index in women with CE before treatment was 0.7-1.08 (0.92 ± 0.04) RU, after - 1.1-1.7 (1.58 ± 0.08) RU, which practically corresponded to the norm. The structure of endometrial tissues in the norm (metabolic aerobicity and morphometric - the level of proliferative activity of the endometrium in three examined endometrial zones) was well expressed. Signs of EHP are characterized by an enhanced intensity of fluorescent signal by 2-10 times at its different parts (fundus, body, internal orifice), some shift of the peak fluorescence signal by 5-10 nm to the right (in 25-30% of patients), impairment of the spectral structure in practically all patients. This was associated with a high proliferative activity of epithelial cells. The values of aerobicity and microcirculation in the endometrium were decreased in practically all uterine regions by 25-55%. During rehabilitation measures, all the above parameters normalized. Analysis of clinical data after PAT has shown that in most patients (59 = 86.76%) the character of menses changed - the period became longer by 2 to 3.5-4 days, the previously scanty volume of menstural blood loss increased, the colour menogramme changed for physiological one. Complaints of pathological discharge and discomfort in the vagina stopped. Ultrasonography showed the correspondence of the echographic picture of the endometrium to the menstrual cycle phase in 54 (79.4%) women. Morphological examination has not found EHP signs in any patient. Conclusion. The results of the study are indicative of a high diagnostic value of non-invasive laser express diagnostics of inflammatory and hyperplastic processes in the endometrium, a marked therapeutic effect of high-volume PAT in treatment of women with EHP in combination with CE

Laser conversion express diagnostics and high-volume photoactive therapy of endometrial hyperplastic processes

The objective. Assessment of the effectiveness of laser fluorescence conversion spectroscopy and high-volume photo-active (photodynamic and photo-immune) therapy in diagnosis and treatment of endometrial hyperplastic processes (EHP) in infertile women on the programmes of assisted reproductive technologies (ART). Patients and methods. A clinical-laboratory examination and treatment of 68 female patients aged 35-47 (41.15 ± 2.18) years with primary and secondary infertility, CE and various forms of EHP was performed. All women underwent planned routine examination before an IFV programme. The control group consisted of 10 healthy women, who were preparing for ART. Ultrasound examination of the pelvic organs was performed in all patients using colour Doppler mapping with assessment of flow rate curves in vessels of the small pelvis. Also, bacteriological and cytological examinations were performed. The main monitoring method of assessment of the morphofunctional state of the endometrium was laser fluorescence conversion diagnostics of the endometrium. High-volume complex photo-active therapy (PAT) was performed under the control of laser conversion diagnostics (LCD) (fluorescent constituent) on a certified device «EnSpectr M» with the use of chlorophyll-containing preparation for oral use 0.5-3.0 ml daily with preliminary processing by laser radiation with wavelength 0.63 μm in the dose 20-40 J/cm2 for 4-6 wks. Results. Fluorescence of a normal endometrium (proliferative activity) was 6-8 x 107-108 RFU. The aerobicity index in women with CE before treatment was 0.7-1.08 (0.92 ± 0.04) RU, after - 1.1-1.7 (1.58 ± 0.08) RU, which practically corresponded to the norm. The structure of endometrial tissues in the norm (metabolic aerobicity and morphometric - the level of proliferative activity of the endometrium in three examined endometrial zones) was well expressed. Signs of EHP are characterized by an enhanced intensity of fluorescent signal by 2-10 times at its different parts (fundus, body, internal orifice), some shift of the peak fluorescence signal by 5-10 nm to the right (in 25-30% of patients), impairment of the spectral structure in practically all patients. This was associated with a high proliferative activity of epithelial cells. The values of aerobicity and microcirculation in the endometrium were decreased in practically all uterine regions by 25-55%. During rehabilitation measures, all the above parameters normalized. Analysis of clinical data after PAT has shown that in most patients (59 = 86.76%) the character of menses changed - the period became longer by 2 to 3.5-4 days, the previously scanty volume of menstural blood loss increased, the colour menogramme changed for physiological one. Complaints of pathological discharge and discomfort in the vagina stopped. Ultrasonography showed the correspondence of the echographic picture of the endometrium to the menstrual cycle phase in 54 (79.4%) women. Morphological examination has not found EHP signs in any patient. Conclusion. The results of the study are indicative of a high diagnostic value of non-invasive laser express diagnostics of inflammatory and hyperplastic processes in the endometrium, a marked therapeutic effect of high-volume PAT in treatment of women with EHP in combination with CE