84 research outputs found
<Abstract of published report>Nucleophilic Vinylic Substitutions of (Z)-(β-(Phenylsulfonyl)alkenyl)-iodonium Tetrafluoroborates with Tetrabutylammonium Halides : Retention of Configuration.
<Abstract of published report>Synthesis of (Z)-1,2-Dihalo-1-alkenes by the Reaction of (Z)-(β-Halovinyl)phenyliodonium Salts with n-Bu_4NX or KX/CuX. : Competitions between Nucleophilic Vinylic Substitutions and Aromatic Substitutions.
<Abstract of published report>Stereoselective Synthesis of Highly Labile(Z)-β-Alkylvinyl(phenyl) iodonium Perchlorates.
<Abstract of published report>Michael Type Addition of Halides to Alkynyl(phenyl)iodonium Tetrafluoroborates. : Stereoselective Synthesis of (Z)-β-Halovinyl(phenyl)-iodonium Halides.
A novel nucleoid protein of Escherichia coli induced under anaerobiotic growth conditions
A systematic search was performed for DNA-binding sequences of YgiP, an uncharacterized transcription factor of Escherichia coli, by using the Genomic SELEX. A total of 688 YgiP-binding loci were identified after genome-wide profiling of SELEX fragments with a high-density microarray (SELEX-chip). Gel shift and DNase-I footprinting assays indicated that YgiP binds to multiple sites along DNA probes with a consensus GTTNATT sequence. Atomic force microscope observation indicated that at low concentrations, YgiP associates at various sites on DNA probes, but at high concentrations, YgiP covers the entire DNA surface supposedly through protein–protein contact. The intracellular concentration of YgiP is very low in growing E. coli cells under aerobic conditions, but increases more than 100-fold to the level as high as the major nucleoid proteins under anaerobic conditions. An E. coli mutant lacking ygiP showed retarded growth under anaerobic conditions. High abundance and large number of binding sites together indicate that YgiP is a nucleoid-associated protein with both architectural and regulatory roles as the nucleoid proteins Fis and IHF. We then propose that YgiP is a novel nucleoid protein of E. coli under anaerobiosis and propose to rename it Dan (DNA-binding protein under anaerobic conditions)
High prevalence of CDH23 mutations in patients with congenital high-frequency sporadic or recessively inherited hearing loss
A New Ranking Model Using the Power Method
In a previous study, we presented two rankings, Ranking(I) and Ranking(II), and their mathematical structures. In the present paper, a new ranking, denoted as Ranking(III), is presented, and a solution that avoids the rank inversion problem that may occur when applying Ranking(I) or Ranking(II) is given
On the Submultiplicative classes : Dedicated to Professor Kentaro MURATA on his 60th birthday
A Mathematical Structure of Processes for Generating Rankings Through the Use of Nonnegative Irreducible Matrices
In our previous study, focusing on a ranking determination, we developed two ranking models. The foundation of these ranking models is derived from either one of the two ranking methods, denoted by Ranking (I) and Ranking (II), that were proposed in our previous papers. The purpose of this paper is to analyze the mathematical structure in the process of generating Ranking (I) and Ranking (II) in detail and to study the properties of the two ranking methods
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