6,898 research outputs found
Boundaries of Disk-like Self-affine Tiles
Let be a disk-like self-affine tile generated by an
integral expanding matrix and a consecutive collinear digit set , and let be the characteristic polynomial of . In the
paper, we identify the boundary with a sofic system by
constructing a neighbor graph and derive equivalent conditions for the pair
to be a number system. Moreover, by using the graph-directed
construction and a device of pseudo-norm , we find the generalized
Hausdorff dimension where
is the spectral radius of certain contact matrix . Especially,
when is a similarity, we obtain the standard Hausdorff dimension where is the largest positive zero of
the cubic polynomial , which is simpler than
the known result.Comment: 26 pages, 11 figure
Axion Protection from Flavor
The QCD axion fails to solve the strong CP problem unless all explicit PQ
violating, Planck-suppressed, dimension n<10 operators are forbidden or have
exponentially small coefficients. We show that all theories with a QCD axion
contain an irreducible source of explicit PQ violation which is proportional to
the determinant of the Yukawa interaction matrix of colored fermions.
Generically, this contribution is of low operator dimension and will
drastically destabilize the axion potential, so its suppression is a necessary
condition for solving the strong CP problem. We propose a mechanism whereby the
PQ symmetry is kept exact up to n=12 with the help of the very same flavor
symmetries which generate the hierarchical quark masses and mixings of the SM.
This "axion flavor protection" is straightforwardly realized in theories which
employ radiative fermion mass generation and grand unification. A universal
feature of this construction is that the heavy quark Yukawa couplings are
generated at the PQ breaking scale.Comment: 16 pages, 2 figure
Vertical Field Effect Transistor based on Graphene-WS2 Heterostructures for flexible and transparent electronics
The celebrated electronic properties of graphene have opened way for
materials just one-atom-thick to be used in the post-silicon electronic era. An
important milestone was the creation of heterostructures based on graphene and
other two-dimensional (2D) crystals, which can be assembled in 3D stacks with
atomic layer precision. These layered structures have already led to a range of
fascinating physical phenomena, and also have been used in demonstrating a
prototype field effect tunnelling transistor - a candidate for post-CMOS
technology. The range of possible materials which could be incorporated into
such stacks is very large. Indeed, there are many other materials where layers
are linked by weak van der Waals forces, which can be exfoliated and combined
together to create novel highly-tailored heterostructures. Here we describe a
new generation of field effect vertical tunnelling transistors where 2D
tungsten disulphide serves as an atomically thin barrier between two layers of
either mechanically exfoliated or CVD-grown graphene. Our devices have
unprecedented current modulation exceeding one million at room temperature and
can also operate on transparent and flexible substrates
Application of Graphene within Optoelectronic Devices and Transistors
Scientists are always yearning for new and exciting ways to unlock graphene's
true potential. However, recent reports suggest this two-dimensional material
may harbor some unique properties, making it a viable candidate for use in
optoelectronic and semiconducting devices. Whereas on one hand, graphene is
highly transparent due to its atomic thickness, the material does exhibit a
strong interaction with photons. This has clear advantages over existing
materials used in photonic devices such as Indium-based compounds. Moreover,
the material can be used to 'trap' light and alter the incident wavelength,
forming the basis of the plasmonic devices. We also highlight upon graphene's
nonlinear optical response to an applied electric field, and the phenomenon of
saturable absorption. Within the context of logical devices, graphene has no
discernible band-gap. Therefore, generating one will be of utmost importance.
Amongst many others, some existing methods to open this band-gap include
chemical doping, deformation of the honeycomb structure, or the use of carbon
nanotubes (CNTs). We shall also discuss various designs of transistors,
including those which incorporate CNTs, and others which exploit the idea of
quantum tunneling. A key advantage of the CNT transistor is that ballistic
transport occurs throughout the CNT channel, with short channel effects being
minimized. We shall also discuss recent developments of the graphene tunneling
transistor, with emphasis being placed upon its operational mechanism. Finally,
we provide perspective for incorporating graphene within high frequency
devices, which do not require a pre-defined band-gap.Comment: Due to be published in "Current Topics in Applied Spectroscopy and
the Science of Nanomaterials" - Springer (Fall 2014). (17 pages, 19 figures
Tolerability and Safety Profile of Cariprazine in Treating Psychotic Disorders, Bipolar Disorder and Major Depressive Disorder: A Systematic Review with Meta-Analysis of Randomized Controlled Trials
BACKGROUND: Cariprazine is a novel antipsychotic agent recently approved for treating schizophrenia and bipolar mania in the USA. The sample sizes of published randomized controlled trials (RCTs) of the drug are small; previous meta-analyses included few RCTs and did not specifically investigate the tolerability/safety profile of cariprazine. OBJECTIVE: Our objective was to conduct a meta-analysis of published RCTs to systematically review the tolerability and safety of cariprazine versus placebo. METHODS: We searched the clinical trial registers (the metaRegister of controlled trials, ClinicalTrials.gov and the World Health Organization International Clinical Trials Registry Platform) and electronic databases (PubMed, Embase, PsycINFO and Cochrane library) up to June 2016 to identify phase II/III RCTs of cariprazine in patients with schizophrenia, bipolar disorder or major depressive disorder. We conducted a meta-analysis to investigate outcomes, including risks of discontinuation due to adverse events (AEs), extrapyramidal side effects (EPS) or related events, metabolic syndrome and cardiovascular-related events. RESULTS: We included nine RCTs, with a total of 4324 subjects. The risk of discontinuation due to AEs for cariprazine was similar to that for placebo (risk ratio [RR] 1.13, 95Â % confidence interval [CI] 0.77-1.66). Cariprazine was associated with higher risks of EPS-related events than was placebo, including risk of akathisia (RR 3.92, 95Â % CI 2.83-5.43), tremor (RR 2.41, 95Â % CI 1.53-3.79) and restlessness (RR 2.17, 95Â % CI 1.38-3.40). The cariprazine treatment group was more likely to have clinically significant weight gain (RR 1.68, 95Â % CI 1.12-2.52). No statistically significant differences in results were found in other metabolic parameters or cardiovascular-related events. CONCLUSION: There was a statistically significant higher risk of EPS-related AEs and a slight increase in mean body weight with cariprazine. There were no statistically significant effects on prolactin level or cardiovascular parameters. EPSs were the main short-term adverse reactions reported in the limited number of patients studied. Further clinical and post-marketing pharmacovigilance studies are needed to investigate the long-term safety of cariprazine
Neutrino masses from new generations
We reconsider the possibility that Majorana masses for the three known
neutrinos are generated radiatively by the presence of a fourth generation and
one right-handed neutrino with Yukawa couplings and a Majorana mass term. We
find that the observed light neutrino mass hierarchy is not compatible with low
energy universality bounds in this minimal scenario, but all present data can
be accommodated with five generations and two right-handed neutrinos. Within
this framework, we explore the parameter space regions which are currently
allowed and could lead to observable effects in neutrinoless double beta decay,
conversion in nuclei and experiments. We
also discuss the detection prospects at LHC.Comment: 28 pages, 4 figures. Version to be published. Some typos corrected.
Improved figures 3 and
P-odd and CP-odd Four-Quark Contributions to Neutron EDM
In a class of beyond-standard-model theories, CP-odd observables, such as the
neutron electric dipole moment, receive significant contributions from
flavor-neutral P-odd and CP-odd four-quark operators. However, considerable
uncertainties exist in the hadronic matrix elements of these operators strongly
affecting the experimental constraints on CP-violating parameters in the
theories. Here we study their hadronic matrix elements in combined chiral
perturbation theory and nucleon models. We first classify the operators in
chiral representations and present the leading-order QCD evolutions. We then
match the four-quark operators to the corresponding ones in chiral hadronic
theory, finding symmetry relations among the matrix elements. Although this
makes lattice QCD calculations feasible, we choose to estimate the
non-perturbative matching coefficients in simple quark models. We finally
compare the results for the neutron electric dipole moment and P-odd and CP-odd
pion-nucleon couplings with the previous studies using naive factorization and
QCD sum rules. Our study shall provide valuable insights on the present
hadronic physics uncertainties in these observables.Comment: 40 pages, 7 figures. This is the final version. A discussion of the
uncertainty of the calculation is adde
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