983 research outputs found
The Glass Transition in Driven Granular Fluids: A Mode-Coupling Approach
We consider the stationary state of a fluid comprised of inelastic hard
spheres or disks under the influence of a random, momentum-conserving external
force. Starting from the microscopic description of the dynamics, we derive a
nonlinear equation of motion for the coherent scattering function in two and
three space dimensions. A glass transition is observed for all coefficients of
restitution, epsilon, at a critical packing fraction, phi_c(epsilon), below
random close packing. The divergence of timescales at the glass-transition
implies a dependence on compression rate upon further increase of the density -
similar to the cooling rate dependence of a thermal glass. The critical
dynamics for coherent motion as well as tagged particle dynamics is analyzed
and shown to be non-universal with exponents depending on space dimension and
degree of dissipation.Comment: 16 pages, 9 figure
Partitioning of energy in highly polydisperse granular gases
A highly polydisperse granular gas is modeled by a continuous distribution of
particle sizes, a, giving rise to a corresponding continuous temperature
profile, T(a), which we compute approximately, generalizing previous results
for binary or multicomponent mixtures. If the system is driven, it evolves
towards a stationary temperature profile, which is discussed for several
driving mechanisms in dependence on the variance of the size distribution. For
a uniform distribution of sizes, the stationary temperature profile is
nonuniform with either hot small particles (constant force driving) or hot
large particles (constant velocity or constant energy driving). Polydispersity
always gives rise to non-Gaussian velocity distributions. Depending on the
driving mechanism the tails can be either overpopulated or underpopulated as
compared to the molecular gas. The deviations are mainly due to small
particles. In the case of free cooling the decay rate depends continuously on
particle size, while all partial temperatures decay according to Haff's law.
The analytical results are supported by event driven simulations for a large,
but discrete number of species.Comment: 10 pages; 5 figure
Drosophila bloom helicase maintains genome integrity by inhibiting recombination between divergent DNA sequences
DNA double strand breaks (DSB) can be repaired either via a sequence independent joining of DNA ends or via homologous recombination. We established a detection system in D. melanogaster to investigate the impact of sequence constraints on the usage of the homology based DSB repair via single strand annealing (SSA), which leads to recombination between direct repeats with concomitant loss of one repeat copy. First of all, we find the SSA frequency to be inversely proportional to the spacer length between the repeats, for spacers up to 2.4 kb in length. We further show that SSA between divergent repeats (homeologous SSA) is suppressed in cell cultures and in vivo in a sensitive manner, recognizing sequence divergences smaller than 0.5%. Finally, we demonstrate that the suppression of homeologous SSA depends on the Bloom helicase (Blm), encoded by the Drosophila gene mus309. Suppression of homeologous recombination is a novel function of Blm in ensuring genomic integrity, not described to date in mammalian systems. Unexpectedly, distinct from its function in S. cerevisiae, the mismatch repair (MMR) factor Msh2 encoded by spel1 does not suppress homeologous SSA in Drosophil
Recommended from our members
Dental Fluoride Varnish Application During Medical Visits Among Children Who Are Privately Insured
This cross-sectional study examines fluoride varnish application rates during well-child medical visits and identify characteristics associated with fluoride varnish receipt
North Carolina Physician-Based Preventive Oral Health Services Improve Access And Use Among Young Medicaid Enrollees
To combat disparities in oral health and access to dental care among infants and toddlers, most state Medicaid programs now reimburse physician-based preventive oral health services, such as fluoride varnish applications. We used geospatial data to examine the distribution of dental and medical Medicaid providers of pediatric oral health services throughout North Carolina to determine if these services have improved access to care for Medicaid enrollees younger than three years old. We then used claims data to examine the association between distance from these practices and use of dental services for a cohort of approximately 1,000 young children. Among 100 counties, four counties had no physician-based preventive oral health services and nine counties had no dental practice. While children who lived further from the nearest dental practice were less likely to make dental visits, distance from physician-based preventive oral health services did not predict use. For young Medicaid enrollees, oral health services provided in medical offices can improve access and increase use
Recommended from our members
Metabolic balance of coastal Antarctic waters revealed by autonomous pCO2 and ΔO2/Ar measurements
Author Posting. © American Geophysical Union, 2014. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geophysical Research Letters 41 (2014): 6803–6810, doi:10.1002/2014GL061266.We use autonomous gas measurements to examine the metabolic balance (photosynthesis minus respiration) of coastal Antarctic waters during the spring/summer growth season. Our observations capture the development of a massive phytoplankton bloom and reveal striking variability in pCO2 and biological oxygen saturation (ΔO2/Ar) resulting from large shifts in community metabolism on time scales ranging from hours to weeks. Diel oscillations in surface gases are used to derive a high-resolution time series of net community production (NCP) that is consistent with 14C-based primary productivity estimates and with the observed seasonal evolution of phytoplankton biomass. A combination of physical mixing, grazing, and light availability appears to drive variability in coastal Antarctic NCP, leading to strong shifts between net autotrophy and heterotrophy on various time scales. Our approach provides insight into the metabolic responses of polar ocean ecosystems to environmental forcing and could be employed to autonomously detect climate-dependent changes in marine primary productivity.This study was supported by funds from the U.S. National Science Foundation (OPP awards ANT-0823101, ANT-1043559, ANT-1043593, and ANT-1043532) as well as support for PDT and ECA from the National Science and Engineering Research Council of Canada.2015-04-0
Visualization of Diffusion within Nanoarrays
The direct experimental characterization of diffusion processes at nanoscale remains a challenge that could help elucidate processes in biology, medicine and technology. In this report, two experimental approaches were employed to visualize ion diffusion profiles at the orifices of nanopores (radius (ra) of 86 ± 6 nm) in array format: (1) electrochemically assisted formation of silica deposits based on surfactant ion transfer across nanointerfaces between two immiscible electrolyte solutions (nanoITIES); (2) combined atomic force - scanning electrochemical microscopy (AFM-SECM) imaging of topography and redox species diffusion through the nanopores. The nature of the diffusion zones formed around the pores is directly related to the interpore distance within the array. Nanopore arrays with different ratios of pore center-to-center separation (rc) to pore radius (ra) were fabricated by focused ion beam (FIB) milling of silicon nitride (SiN) membranes, with 100 pores in a hexagonal arrangement. The ion diffusion profiles determined by the two visualization methods indicated the formation of overlapped or independent diffusion profiles at nanopore arrays with rc/ra ratios of 21 ± 2 and 91 ± 7, respectively. In particular, the silica deposition method resulted in formation of a single deposit encompassing the complete array with closer nanopore arrangement, whereas individual silica deposits were formed around each nanopore within the more widely spaced array. The methods reveal direct experimental evidence of diffusion zones at nanopore arrays and provide practical illustration that the pore-pore separation within such arrays has a significant impact on diffusional transport as the pore size is reduced to the nanoscale. These approaches to nanoscale diffusion zone visualization open up possibilities for better understanding of molecular transport processes within miniaturized systems
Quantum point contact on graphite surface
The conductance through a quantum point contact created by a sharp and hard
metal tip on the graphite surface has features which to our knowledge have not
been encountered so far in metal contacts or in nanowires. In this paper we
first investigate these features which emerge from the strongly directional
bonding and electronic structure of graphite, and provide a theoretical
understanding for the electronic conduction through quantum point contacts. Our
study involves the molecular-dynamics simulations to reveal the variation of
interlayer distances and atomic structure at the proximity of the contact that
evolves by the tip pressing toward the surface. The effects of the elastic
deformation on the electronic structure, state density at the Fermi level, and
crystal potential are analyzed by performing self-consistent-field
pseudopotential calculations within the local-density approximation. It is
found that the metallicity of graphite increases under the uniaxial compressive
strain perpendicular to the basal plane. The quantum point contact is modeled
by a constriction with a realistic potential. The conductance is calculated by
representing the current transporting states in Laue representation, and the
variation of conductance with the evolution of contact is explained by taking
the characteristic features of graphite into account. It is shown that the
sequential puncturing of the layers characterizes the conductance.Comment: LaTeX, 11 pages, 9 figures (included), to be published in Phys. Rev.
B, tentatively scheduled for 15 September 1998 (Volume 58, Number 12
The Gas Content in Galactic Disks: Correlation with Kinematics
We consider the relationship between the total HI mass in late-type galaxies
and the kinematic properties of their disks. The mass for galaxies with
a wide variety of properties, from dwarf dIrr galaxies with active star
formation to giant low-brightness galaxies, is shown to correlate with the
product ( is the rotational velocity, and is the radial
photometric disks scale length), which characterizes the specific angular
momentum of the disk. This relationship, along with the anticorrelation between
the relative mass of HI in a galaxy and , can be explained in terms of the
previously made assumption that the gas density in the disks of most galaxies
is maintained at a level close to the threshold (marginal) stability of a
gaseous layer to local gravitational perturbations. In this case, the
regulation mechanism of the star formation rate associated with the growth of
local gravitational instability in the gaseous layer must play a crucial role
in the evolution of the gas content in the galactic disk.Comment: revised version to appear in Astronomy Letters, 8 pages, 5 EPS
figure
- …