Two-loop Renormalization in Quantum Gravity near Two Dimensions

We study two--loop renormalization in $(2+\epsilon)$--dimensional quantum gravity. As a first step towards the full calculation, we concentrate on the divergences which are proportional to the number of matter fields. We calculate the $\beta$ functions and show how the nonlocal divergences as well as the infrared divergences cancel among the diagrams. Although the formalism includes a subtlety concerning the general covariance due to the dynamics of the conformal mode, we find that the renormalization group allows the existence of a fixed point which possesses the general covariance. Our results strongly suggest that we can construct a consistent theory of quantum gravity by the $\epsilon$ expansion around two dimensions.Comment: 31 pages including 14 figures in uufile forma

Fractal Structure in Two-Dimensional Quantum Regge Calculus

We study the fractal structure of the surface in two-dimensional quantum Regge calculus by performing Monte Carlo simulation with up to 200,000 triangles. The result can be compared with the universal scaling function obtained analytically in the continuum limit of dynamical triangulation, which provides us with a definite criterion whether Regge calculus serves as a proper regularization of quantum gravity. When the scale-invariant measure is taken as the measure of the link-length integration, we observe the correct scaling behavior in the data for the type of loop attached to a baby universe. The data seem to converge to the universal scaling function as the number of triangles is increased. The data for the type of loop attached to the mother universe, on the other hand, shows no scaling behavior up to the present size.Comment: 13 pages + 8 figures, LaTeX, UT-683, KEK-TH-401 (double-spacing command removed. sorry.

Double strand break repair by capture of retrotransposon sequences and reverse-transcribed spliced mRNA sequences in mouse zygotes

Ono, R., Ishii, M., Fujihara, Y. et al. Double strand break repair by capture of retrotransposon sequences and reverse-transcribed spliced mRNA sequences in mouse zygotes. Sci Rep 5, 12281 (2015). https://doi.org/10.1038/srep1228

Comments on gap anisotropy and nodal constant Fermi velocity in a superconductor, BSCCO

On the basis of both the inhomogeneity of a superconductor, BSCCO-2212, and the effect of measurement, we reveal that an anomalously large gap anisotropy known as evidence of dx2-y2-wave symmetry [Phys. Rev. Lett. 70 (1993) 1553] is not intrinsic, and that the constant Fermi velocity at node as an unsolved problem [Nature 423 (2003) 398] is due to the dx2-y2-wave insulator-metal transition.Comment: 2 pages, 2 figure

Quantum Criticality in YbCu4Ni

We report on the quantum criticality of YbCu$_4$Ni as revealed by our combined micro- and macro-measurements. We determine the crystal structure of YbCu$_4$Ni with site mixing by neutron diffraction measurements, which suggests the possible presence of Kondo disorder. However, decreasing the local spin susceptibility distribution and the development of spin fluctuations below 10 K at ambient pressure by muon spin rotation and relaxation measurements suggests that YbCu4Ni exhibits quantum criticality. Therefore, our experimental results indicate that YbCu4Ni is a new material that exhibits quantum criticality under a zero magnetic field and ambient pressure.Comment: 8 pages, 5 figure

Testing a novel large-N reduction for N=4 super Yang-Mills theory on RxS^3

Recently a novel large-N reduction has been proposed as a maximally supersymmetric regularization of N=4 super Yang-Mills theory on RxS^3 in the planar limit. This proposal, if it works, will enable us to study the theory non-perturbatively on a computer, and hence to test the AdS/CFT correspondence analogously to the recent works on the D0-brane system. We provide a nontrivial check of this proposal by performing explicit calculations in the large-N reduced model, which is nothing but the so-called plane wave matrix model, around a particular stable vacuum corresponding to RxS^3. At finite temperature and at weak coupling, we reproduce precisely the deconfinement phase transition in the N=4 super Yang-Mills theory on RxS^3. This phase transition is considered to continue to the strongly coupled regime, where it corresponds to the Hawking-Page transition on the AdS side. We also perform calculations around other stable vacua, and reproduce the phase transition in super Yang-Mills theory on the corresponding curved space-times such as RxS^3/Z_q and RxS^2.Comment: 24 pages, 4 figure

Successful conservative treatment for massive uterine bleeding with non-septic disseminated intravascular coagulation after termination of early pregnancy in a woman with huge adenomyosis: case report.

BACKGROUND:Adenomyosis is a benign gynecological condition in which endometrial tissue or endometrial-like tissue develops within the uterine myometrium. Few cases of disseminated intravascular coagulation has been reported in the patients with adenomyosis. Although hysterectomy is indicated for refractory massive uterine bleeding in the patients with advanced uterine adenomyosis, conservative treatment is often desired in women in the late reproductive age. Recently such cases are increasing due to the social trend of late marriage.CASE PRESENTATION:A 37-year-old woman with huge adenomyosis, gravida 2 para 0, was referred to our hospital to terminate her pregnancy. Acute, non-septic, disseminated intravascular coagulation (DIC) developed after early pregnancy was terminated in a woman with huge adenomyosis. Massive bleeding and DIC occurred 3 days after the dilatation and curettage. There was no evidence of infection as the cause of the DIC, because neither bacteria nor endotoxin could be detected in her blood, and antithrombin 3 (AT3), which would be expected to decrease in septic patients, was not decreased. Hemorrhage in the adenomyotic tissue after the termination presumably developed inflammation, with numerous microthrombi and necrosis in the adenomyotic tissue, which subsequently promoted coagulation and fibrinolysis, leading to the onset of massive uterine bleeding and DIC. Although severe hyperfibrinolysis is observed in peripheral blood, the fibrinolysis state in the uterine myometrium is considered to be even more severe. The newly formed clots for hemostasis under the uterine mucosa could be removed due to the excessive activation of fibrinolytic system happened in the adjacent myometrium, leading to the onset of massive uterine bleeding. Massive bleeding and DIC resolved quickly after the patient was treated with nafamostat mesilate, which is effective for both excessive coagulation and fibrinolysis.CONCLUSIONS:Adenomyosis could cause massive bleeding and DIC when pregnancy is terminated. Massive bleeding was considered to occur because the excessive fibrinolysis system inside adenomyosis affected the adjacent endometrium. Before considering hysterectomy to control refractory uterine bleeding, nafamostat mesilate should be considered as one option, thinking the pathophysiology of the massive bleeding due to uterine adenomyosis

Histone functions as a cell-surface receptor for AGEs

peer reviewedReducing sugars can covalently react with proteins to generate a heterogeneous and complex group of compounds called advanced glycation end products (AGEs). AGEs are generally considered as pathogenic molecules, mediating a pro-inflammatory response and contributing to the development of a number of human diseases. However, the intrinsic function of AGEs remains to be elucidated. We now provide multiple lines of evidence showing that AGEs can specifically bind histone localized on the cell surface as an AGE-binding protein, regulate the function of histone as a plasminogen receptor, and result in the regulation of monocytes/macrophage recruitment to the site of inflammation. Our finding of histone as a cell-surface receptor for AGEs suggests that, beside our common concept of AGEs as danger-associated molecular patterns mediating a pro-inflammatory response, they may also be involved in the homeostatic response via binding to histone. Advanced glycation end products (AGEs) are believed to be pathogenic molecules that mediate pro-inflammatory responses. Here the authors identify histone as a cell-surface receptor for AGEs and show that AGEs may also be involved in the homeostatic response via binding to histone