147 research outputs found
The long-term course of shoulder complaints:a prospective study in general practice
Objective. Assessment of the long-term course of shoulder complaints in patients in general practice with special focus on changes in diagnostic category and fluctuations in the severity of the complaints. Design. Prospective descriptive study. Setting. Four general practices in The Netherlands. Method. All patients (101) with shoulder complaints seen in a 5 month period were included. Assessment took place 26 weeks and 12-18 months after inclusion in the study with a pain questionnaire and a physical examination. Results. A total of 51% of the patients experienced (mostly recurrent) complaints after 26 weeks and 41% after 12-18 months. Diagnostic changes were found over the course of time, mostly from synovial disorders towards functional disorders of the structures of the shoulder girdle, but also the other way round. Although 52 of the 101 patients experienced complaints in week 26, 62% of those patients considered themselves 'cured'. After 12-18 months, 51% of the 39 patients experiencing complaints felt 'cured'. Conclusion. Many patients seen with shoulder complaints in general practice have recurrent complaints. The nature of these complaints varies considerably over the course of time, leading to changes in diagnostic category. Because of the fluctuating severity of the complaints over time, feeling 'cured' or not 'cured' is also subject to change over time
The response of temperate aquatic ecosystems to global warming: novel insights from a multidisciplinary project
This article serves as an introduction to this special issue of Marine Biology, but also as a review of the key findings of the AQUASHIFT research program which is the source of the articles published in this issue. AQUASHIFT is an interdisciplinary research program targeted to analyze the response of temperate zone aquatic ecosystems (both marine and freshwater) to global warming. The main conclusions of AQUASHIFT relate to (a) shifts in geographic distribution, (b) shifts in seasonality, (c) temporal mismatch in food chains, (d) biomass responses to warming, (e) responses of body size, (f) harmful bloom intensity, (f), changes of biodiversity, and (g) the dependence of shifts to temperature changes during critical seasonal windows
Impulsive behaviour induced by both NMDA receptor antagonism and GABAA receptor activation in rat ventromedial prefrontal cortex
EficĂĄcia do exercĂcio fĂsico na fadiga dos pacientes com cĂąncer durante o tratamento ativo: revisĂŁo sistemĂĄtica e meta-anĂĄlise
El objetivo del estudio fue determinar la efectividad del ejercicio fĂsico en la fatiga de pacientes con cĂĄncer durante el tratamiento activo. Las bases de datos de PubMed Central, EMBASE y OVID fueron consultadas hasta abril de 2014 para identificar ensayos clĂnicos aleatorizados, que evaluaran el efecto del ejercicio en la fatiga de pacientes con cĂĄncer sometidos a tratamiento activo. Once estudios (n = 1.407) fueron incluidos. La quimioterapia fue el tratamiento mĂĄs comĂșn (n = 1.028). Los estudios tuvieron bajo riesgo de sesgo y alta calidad metodolĂłgica. Las estimaciones de efecto mostraron que el ejercicio fĂsico mejorĂł significativamente la fatiga (SMD = -3,0; IC95%: -5,21; -0,80), p < 0,0001. Se encontraron efectos similares para el entrenamiento de resistencia (SMD = -4,5; IC95%: -7,24; -1,82), p = 0,001. Se encontraron mejoras significativas en pacientes con cĂĄncer de mama y de prĂłstata (p < 0,05). El ejercicio es una intervenciĂłn segura y eficaz en el control de la fatiga en pacientes sometidos a tratamiento activoThis study aimed to determine the effectiveness of physical exercise in decreasing fatigue in cancer patients during active treatment. The PubMed Central, EMBASE, and OVID databases were consulted up to April 2014 to identify randomized clinical trials that evaluated the effect of exercise on fatigue in cancer patients undergoing active treatment. Eleven studies (n = 1,407) were included. Chemotherapy was the most common form of treatment (n = 1,028). The studies showed a low risk of bias and high methodological quality. Effect estimates showed that physical exercise significantly improved fatigue (SMD = -3.0; 95%CI: -5.21; -0.80), p < 0.0001. Similar effects were found for resistance training (SMD = -4.5; 95%CI: -7.24; -1.82), p = 0.001. Significant improvements were found in breast and prostate cancer patients (p < 0.05). Exercise is a safe and effective intervention in the management fatigue in cancer patients undergoing active treatmentO objetivo foi determinar a efetividade do exercĂcio fĂsico sobre a fadiga em pacientes com cĂąncer durante o tratamento ativo. As bases de dados PubMed Central, EMBASE e OVID foram consultadas atĂ© abril de 2014 para identificar ensaios clĂnicos randomizados que avaliaram o efeito do exercĂcio sobre a fadiga em pacientes com cĂąncer em tratamento ativo. Onze estudos (n = 1.407) foram incluĂdos. A quimioterapia foi o tratamento mais comum (n = 1.028). Os estudos tiveram baixo risco de viĂ©s e alta qualidade metodolĂłgica. As estimativas de efeito mostraram que o exercĂcio melhorou significativamente a fadiga (DMP = -3,0; IC95%: -5,21; -0,80), p < 0,0001. Efeitos semelhantes sobre o treinamento de resistĂȘncia (DMP = -4,5; IC95%: -7,24; -1,82), p = 0,001 foram encontrados. O exercĂcio fĂsico Ă© uma intervenção segura e eficaz contra a fadiga em pacientes submetidos ao tratamento ativoEl presente trabajo forma parte del Proyecto PrĂĄctica del autoexamen de seno y los conocimientos, factores de riesgo y estilos de vida relacionados con el cĂĄncer de mama en mujeres jĂłvenes de la Universidad Santo TomĂĄs de BogotĂĄ: un anĂĄlisis transversal (9ÂȘ Convocatoria FODEIN- CĂłdigo del proyecto 4110060001 - 008)
Comparison of tai chi vs. strength training for fall prevention among female cancer survivors: study protocol for the GET FIT trial
Integral strategy to supportive care in breast cancer survivors through occupational therapy and a m-health system: design of a randomized clinical trial
Background: Technological support using e-health mobile applications (m-health) is a promising strategy to improve
the adherence to healthy lifestyles in breast cancer survivors (excess in energy intake or low physical activity are
determinants of the risk of recurrence, second cancers and cancer mortality). Moreover, cancer rehabilitation
programs supervised by health professionals are needed due to the inherent characteristics of these breast cancer
patients. Our main objective is to compare the clinical efficacy of a m-health lifestyle intervention system alone versus
an integral strategy to improve Quality of Life in breast cancer survivors.
Methods: This therapeutic superiority study will use a two-arm, assessor blinded parallel RCT design. Women will be
eligible if: they are diagnosed of stage I, II or III-A breast cancer; are between 25 and 75 years old; have a Body Mass
Index > 25 kg/m2; they have basic ability to use mobile apps; they had completed adjuvant therapy except for
hormone therapy; and they have some functional shoulder limitations. Participants will be randomized to one of
the following groups: integral group will use a mobile application (BENECA APP) and will receive a face-to-face
rehabilitation (8-weeks); m-health group will use the BENECA app for 2-months and will received usual care
information. Study endpoints will be assessed after 8 weeks and 6 months. The primary outcome will be Quality
of Life measured by The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core
and breast module. The secondary outcomes: body composition; upper-body functionality (handgrip, Disability of the
Arm, Shoulder and Hand questionnaire, goniometry); cognitive function (Wechsler Adult Intelligence Scale, Trail Making
Test); anxiety and depression (Hospital Anxiety and Depression Scale); physical fitness (Short version of the Minnesota
Leisure Time Physical Activity Questionnaire, Self-Efficacy Scale for Physical Activity); accelerometry and lymphedema.
Discussion: This study has been designed to seek to address the new needs for support and treatment of breast cancer
survivors, reflecting the emerging need to merge new low cost treatment options with much-needed involvement of
health professionals in this type of patients.
Trial registration: ClinicalTrials.gov Identifier: NCT02817724 (date of registration: 22/06/2016).The study was funded by the Spanish Ministry of Economy and Competitiveness
(Plan Estatal de I + D + I 2013-2016), Fondo de InvestigaciĂłn Sanitaria del Instituto
de Salud Carlos III (PI14/01627), Fondos Estructurales de la UniĂłn Europea (FEDER)
and by the Spanish Ministry of Education (FPU14/01069). This is part of a Ph.D.
Thesis conducted in the Clinical Medicine and Public Health Doctoral Studies of
the University of Granada, Spain
Study of double-tagged gamma gamma events at LEPII
Double-tagged interactions of photons with virtualities Q^2 between 10 GeV^2
and 200 GeV^2 are studied with the data collected by DELPHI at LEPII from 1998
to 2000, corresponding to an integrated luminosity of 550 pb^{-1}. The gam*
gam* -> mu+mu- data agree with QED predictions. The cross-section of the
reaction gam* gam* -> hadrons is measured and compared to the LO and NLO BFKL
calculations.Comment: 17 pages, 9 figures, Accepted by Eur. Phys. J.
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