463 research outputs found
Níveis séricos de hormônio de crescimento, fator de crescimento símile à insulina e sulfato de deidroepiandrosterona em idosos residentes na comunidade. Correlação com parâmetros clínicos
Aging is associated with body changes, especially related with the endocrine system. The activity of the GH/IGF-1 axis and production of DHEAS decline significantly with aging, compromising body composition, cardiovascular and cognitive functions. We studied 225 elderly subjects from a community cohort (148 women and 77 men, 70 to 91 years) 80% of whom being considered successful (Mini-mental> or = 24 and AVL ou = 24 e comprometimento de atividades de vida diária <=3). Tanto o IMC como a pressão arterial estavam significativamente mais elevados nas mulheres. Os níveis de GH também eram maiores nas mulheres (1,6±1,7 vs. 1,0±1,3ng/ml, X±DP, p<0,001), estando acima da faixa de referência em 14% e 19% das mulheres e homens. Já os níveis de IGF-1 eram semelhantes (90±42 e 101±40ng/ml, NS), não sendo elevados em nenhum deles e reduzidos em 35% e 24%, respectivamente. Os níveis de SDHEA eram maiores nos homens (86±58 e 54±36µg/dl, p<0,001), porém na faixa de referência em 92% deles. Houve uma surpreendente correlação positiva entre idade e GH nos homens (r= 0,38, p<0,005), mas uma correlação negativa entre IGF-1 e idade nos dois grupos (r= -0,24 e r= -0,32). Nas mulheres, houve também uma correlação positiva entre SDHEA e IGF-1 (r= 0,27). Em conclusão, níveis basais de GH podem estar elevados em uma parcela significativa dos idosos, sendo maiores nas mulheres, enquanto os níveis de IGF-1 encontram-se normais ou baixos nos dois grupos, sugerindo quadro de resistência hormonal. Os níveis de SDHEA encontravam-se na faixa de referência, sendo maiores nos homens, caracterizando a perda da contribuição ovariana. Diferentemente do que se tem especulado, não encontramos correlação entre os níveis de SDHEA e qualquer parâmetro clínico investigado.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de MedicinaUNIFESP, EPM, Depto. de MedicinaSciEL
Compact graphene mode-locked wavelength-tunable erbium-doped fiber lasers: from all anomalous dispersion towards all normal dispersion
Soliton operation and soliton wavelength tuning of erbium-doped fiber lasers
mode locked with atomic layer graphene was experimentally investigated under
various cavity dispersion conditions. It was shown that not only wide range
soliton wavelength tuning but also soltion pulse width variation could be
obtained in the fiber lasers. Our results show that the graphene mode locked
erbium-doped fiber lasers provide a compact, user friendly and low cost
wavelength tunable ultrahsort pulse source
Using geospatial technology to strengthen data systems in developing countries: the case of agricultural statistics in India
Despite significant progress in the development of quantitative geography techniques and methods and a general recognition of the need to improve the quality of geographic data, few studies have exploited the potential of geospatial tools to augment the quality of available data methods in developing countries. This paper uses data from an extensive deployment of geospatial technology in India to compare crop areas estimated using geospatial technology to crop areas estimated by conventional methods and assess the differences between the methods. The results presented here show that crop area estimates based on geospatial technology generally exceed the estimates obtained using conventional methods. This suggests that conventional methods are unable to respond quickly to changes in cropping patterns and therefore do not accurately record the area under high-value cash crops. This finding has wider implications for commercializing agriculture and the delivery of farm credit and insurance services in developing countries. Significant data errors found in the conventional methods could affect critical policy interventions such as planning for food security. Some research and policy implications are discussed
Truancy in the United States: Examining temporal trends and correlates by race, age, and gender
Pathways through Adolescenc
From Social Data Mining to Forecasting Socio-Economic Crisis
Socio-economic data mining has a great potential in terms of gaining a better
understanding of problems that our economy and society are facing, such as
financial instability, shortages of resources, or conflicts. Without
large-scale data mining, progress in these areas seems hard or impossible.
Therefore, a suitable, distributed data mining infrastructure and research
centers should be built in Europe. It also appears appropriate to build a
network of Crisis Observatories. They can be imagined as laboratories devoted
to the gathering and processing of enormous volumes of data on both natural
systems such as the Earth and its ecosystem, as well as on human
techno-socio-economic systems, so as to gain early warnings of impending
events. Reality mining provides the chance to adapt more quickly and more
accurately to changing situations. Further opportunities arise by individually
customized services, which however should be provided in a privacy-respecting
way. This requires the development of novel ICT (such as a self- organizing
Web), but most likely new legal regulations and suitable institutions as well.
As long as such regulations are lacking on a world-wide scale, it is in the
public interest that scientists explore what can be done with the huge data
available. Big data do have the potential to change or even threaten democratic
societies. The same applies to sudden and large-scale failures of ICT systems.
Therefore, dealing with data must be done with a large degree of responsibility
and care. Self-interests of individuals, companies or institutions have limits,
where the public interest is affected, and public interest is not a sufficient
justification to violate human rights of individuals. Privacy is a high good,
as confidentiality is, and damaging it would have serious side effects for
society.Comment: 65 pages, 1 figure, Visioneer White Paper, see
http://www.visioneer.ethz.c
A-dependence of nuclear transparency in quasielastic A(e,e'p) at high Q^2
The A-dependence of the quasielastic A(e,e'p) reaction has been studied at
SLAC with H-2, C, Fe, and Au nuclei at momentum transfers Q^2 = 1, 3, 5, and
6.8 (GeV/c)^2. We extract the nuclear transparency T(A,Q^2), a measure of the
average probability that the struck proton escapes from the nucleus A without
interaction. Several calculations predict a significant increase in T with
momentum transfer, a phenomenon known as Color Transparency. No significant
rise within errors is seen for any of the nuclei studied.Comment: 5 pages incl. 2 figures, Caltech preprint OAP-73
The New Urban Revival in the United States
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68657/2/10.1080_00420989320081901.pd
Momentum transfer dependence of nuclear transparency from the quasielastic 12C(e,e’p) reaction
The cross section for quasielastic 12C(e,e’p) scattering has been measured at momentum transfer Q2=1, 3, 5, and 6.8 (GeV/c)2. The results are consistent with scattering from a single nucleon as the dominant process. The nuclear transparency is obtained and compared with theoretical calculations that incorporate color transparency effects. No significant rise of the transparency with Q2 is observed
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