698 research outputs found
High-Intensity Interval Training for Knee Osteoarthritis: A Pilot Study
Objective: To assess the feasibility and changes in outcomes of a 12-week high-intensity interval training (HIIT) program in individuals with symptomatic knee osteoarthritis (OA). Methods: The single-arm trial included 29 participants (mean ± SD age 63 ± 7 years; 66% women; 66% obese). Measures of participant flow, adherence, and tolerability were collected. Pain, function, and balance were assessed at baseline, 6 weeks, and 12 weeks using the Western Ontario and McMaster Universities Osteoarthritis Index, 20-m fast-paced walk test, 30-second chair-stand test, stair-climb test, timed up and go test, and single leg stance. Cardiorespiratory fitness, strength, and body composition were evaluated using peak oxygen consumption (VO2peak), isometric knee extensor/flexor strength, and dual-energy x-ray absorptiometry, respectively. HIIT was completed two times/week (cycling or treadmill) and consisted of 10 repetitions of 1-minute bouts at 90% VO2peak, with 1-minute rest periods. Separate multivariable-adjusted linear mixed models were fit for each outcome with fixed effects of time, age, sex, body mass index, and random effects of baseline values to estimate mean changes and 95% confidence intervals (CIs) between baseline and 12-week assessments. Results: Recruitment aligned with the anticipated enrollment rate, adherence was 70%, and no adverse events were reported. At 12 weeks, improvements were observed for most outcomes, with notable mean changes for the 20-m fast-paced walk (−1.13 [95% CI −1.61 to −0.64] seconds), 30-second chair-stand (2.6 [1.8-3.4] stands), and VO2peak (0.14 [0.03-0.24] liters/minute). Conclusion: In this 12-week pilot study, HIIT improved multiple aspects of health in individuals with knee OA; larger studies are needed
Black-hole quasinormal modes and scalar glueballs in a finite-temperature AdS/QCD model
We use the holographic AdS/QCD soft-wall model to investigate the spectrum of
scalar glueballs in a finite temperature plasma. In this model, glueballs are
described by a massless scalar field in an AdS_5 black hole with a dilaton
soft-wall background. Using AdS/CFT prescriptions, we compute the boundary
retarded Green's function. The corresponding thermal spectral function shows
quasiparticle peaks at low temperatures. We also compute the quasinormal modes
of the scalar field in the soft-wall black hole geometry. The temperature and
momentum dependences of these modes are analyzed. The positions and widths of
the peaks of the spectral function are related to the frequencies of the
quasinormal modes. Our numerical results are found employing the power series
method and the computation of Breit-Wigner resonances.Comment: Revision: Results unchanged. More discussions on the model and on the
results. References added. 28 pages, 7 figures, 5 table
Digital Quantum Simulation with Rydberg Atoms
We discuss in detail the implementation of an open-system quantum simulator
with Rydberg states of neutral atoms held in an optical lattice. Our scheme
allows one to realize both coherent as well as dissipative dynamics of complex
spin models involving many-body interactions and constraints. The central
building block of the simulation scheme is constituted by a mesoscopic Rydberg
gate that permits the entanglement of several atoms in an efficient, robust and
quick protocol. In addition, optical pumping on ancillary atoms provides the
dissipative ingredient for engineering the coupling between the system and a
tailored environment. As an illustration, we discuss how the simulator enables
the simulation of coherent evolution of quantum spin models such as the
two-dimensional Heisenberg model and Kitaev's toric code, which involves
four-body spin interactions. We moreover show that in principle also the
simulation of lattice fermions can be achieved. As an example for controlled
dissipative dynamics, we discuss ground state cooling of frustration-free spin
Hamiltonians.Comment: submitted to special issue "Quantum Information with Neutral
Particles" of "Quantum Information Processing
New Results from the Cryogenic Dark Matter Search Experiment
Using improved Ge and Si detectors, better neutron shielding, and increased
counting time, the Cryogenic Dark Matter Search (CDMS) experiment has obtained
stricter limits on the cross section of weakly interacting massive particles
(WIMPs) elastically scattering from nuclei. Increased discrimination against
electromagnetic backgrounds and reduction of neutron flux confirm
WIMP-candidate events previously detected by CDMS were consistent with neutrons
and give limits on spin-independent WIMP interactions which are >2X lower than
previous CDMS results for high WIMP mass, and which exclude new parameter space
for WIMPs with mass between 8-20 GeV/c^2.Comment: 4 pages, 4 figure
Quantum Computing and Quantum Simulation with Group-II Atoms
Recent experimental progress in controlling neutral group-II atoms for
optical clocks, and in the production of degenerate gases with group-II atoms
has given rise to novel opportunities to address challenges in quantum
computing and quantum simulation. In these systems, it is possible to encode
qubits in nuclear spin states, which are decoupled from the electronic state in
the S ground state and the long-lived P metastable state on the
clock transition. This leads to quantum computing scenarios where qubits are
stored in long lived nuclear spin states, while electronic states can be
accessed independently, for cooling of the atoms, as well as manipulation and
readout of the qubits. The high nuclear spin in some fermionic isotopes also
offers opportunities for the encoding of multiple qubits on a single atom, as
well as providing an opportunity for studying many-body physics in systems with
a high spin symmetry. Here we review recent experimental and theoretical
progress in these areas, and summarise the advantages and challenges for
quantum computing and quantum simulation with group-II atoms.Comment: 11 pages, 7 figures, review for special issue of "Quantum Information
Processing" on "Quantum Information with Neutral Particles
Quantum computing implementations with neutral particles
We review quantum information processing with cold neutral particles, that
is, atoms or polar molecules. First, we analyze the best suited degrees of
freedom of these particles for storing quantum information, and then we discuss
both single- and two-qubit gate implementations. We focus our discussion mainly
on collisional quantum gates, which are best suited for atom-chip-like devices,
as well as on gate proposals conceived for optical lattices. Additionally, we
analyze schemes both for cold atoms confined in optical cavities and hybrid
approaches to entanglement generation, and we show how optimal control theory
might be a powerful tool to enhance the speed up of the gate operations as well
as to achieve high fidelities required for fault tolerant quantum computation.Comment: 19 pages, 12 figures; From the issue entitled "Special Issue on
Neutral Particles
Exclusion limits on the WIMP-nucleon cross-section from the Cryogenic Dark Matter Search
The Cryogenic Dark Matter Search (CDMS) employs low-temperature Ge and Si
detectors to search for Weakly Interacting Massive Particles (WIMPs) via their
elastic-scattering interactions with nuclei while discriminating against
interactions of background particles. For recoil energies above 10 keV, events
due to background photons are rejected with >99.9% efficiency, and surface
events are rejected with >95% efficiency. The estimate of the background due to
neutrons is based primarily on the observation of multiple-scatter events that
should all be neutrons. Data selection is determined primarily by examining
calibration data and vetoed events. Resulting efficiencies should be accurate
to about 10%. Results of CDMS data from 1998 and 1999 with a relaxed
fiducial-volume cut (resulting in 15.8 kg-days exposure on Ge) are consistent
with an earlier analysis with a more restrictive fiducial-volume cut.
Twenty-three WIMP candidate events are observed, but these events are
consistent with a background from neutrons in all ways tested. Resulting limits
on the spin-independent WIMP-nucleon elastic-scattering cross-section exclude
unexplored parameter space for WIMPs with masses between 10-70 GeV c^{-2}.
These limits border, but do not exclude, parameter space allowed by
supersymmetry models and accelerator constraints. Results are compatible with
some regions reported as allowed at 3-sigma by the annual-modulation
measurement of the DAMA collaboration. However, under the assumptions of
standard WIMP interactions and a standard halo, the results are incompatible
with the DAMA most likely value at >99.9% CL, and are incompatible with the
model-independent annual-modulation signal of DAMA at 99.99% CL in the
asymptotic limit.Comment: 40 pages, 49 figures (4 in color), submitted to Phys. Rev. D;
v.2:clarified conclusions, added content and references based on referee's
and readers' comments; v.3: clarified introductory sections, added figure
based on referee's comment
Measurement of the Ds lifetime
We report precise measurement of the Ds meson lifetime. The data were taken
by the SELEX experiment (E781) spectrometer using 600 GeV/c Sigma-, pi- and p
beams. The measurement has been done using 918 reconstructed Ds. The lifetime
of the Ds is measured to be 472.5 +- 17.2 +- 6.6 fs, using K*(892)0K+- and phi
pi+- decay modes. The lifetime ratio of Ds to D0 is 1.145+-0.049.Comment: 5 pages, 2 figures submitted to Phys. Lett.
Confirmation of the Double Charm Baryon Xi_cc+ via its Decay to p D+ K-
We observes a signal for the double charm baryon Xi_cc+ in the charged decay
mode Xi_cc+ -> p D+ K- to complement the previously reported decay Xi_cc+ ->
Lambda_c K- pi+ in data from SELEX, the charm hadro-production experiment
(E781) at Fermilab. In this new decay mode we observe an excess of 5.62 events
over an expected background estimated by event mixing to be 1.38+/-0.13 events.
The Poisson probability that a background fluctuation can produce the apparent
signal is less than 6.4E-4. The observed mass of this state is
(3518+/-3)MeV/c^2, consistent with the published result. Averaging the two
results gives a mass of (3518.7+/-1.7)MeV/c^2. The observation of this new weak
decay mode confirms the previous SELEX suggestion that this state is a double
charm baryon. The relative branching ratio Gamma(Xi_cc+ -> pD+K-)/Gamma(Xi_cc+
-> Lambda_c K- pi+) = 0.36+/-0.21.Comment: 11 pages, 6 included eps figures. v2 includes improved statistical
method to determine significance of observation. Submitted to PL
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