23 research outputs found
Results, meta-analysis and a first evaluation of UNOxR, the urinary nitrate-to-nitrite molar ratio, as a measure of nitrite reabsorption in experimental and clinical settings
Diabetes mellitus: pathophysiological changes and therap
The influence of combined therapy with perindopril and trimetazidine on the silent myocardial ischemia and on left ventricular remodeling in essential hypertension
Effect of normobaric hypoxic exercise on blood pressure in old individuals
Purpose: To test the hypothesis that the combination of endurance training and hypoxia leads to greater improvements in resting and exercise blood pressure in old sedentary individuals compared to endurance training only.
Methods: We randomly assigned 29 old overweight participants (age: 62 ± 6 years, body mass index (BMI): 28.5 ± 0.5 kg/m2, 52% men) to single blind 8-week bicycle exercise in hypoxia (fraction of inspired oxygen (FIO2) = 0.15) or normoxia (FIO2 = 0.21). Brachial blood pressure was measured at rest, during maximal incremental exercise testing, and during a 30 min constant work rate test, at baseline and after the training period.
Results: Work rate, heart rate and perceived exertion during training were similar in both groups, with lower oxygen saturation for participants exercising under hypoxia (88.7 ± 1.5 vs. 96.2 ± 1.2%, t(27) = - 13.04, p < 0.001, |g|= 4.85). Office blood pressure and blood pressure during incremental exercise tests did not change significantly in either group after the training program. Systolic blood pressure during the constant work rate test was reduced after training in hypoxia (160 ± 18 vs. 151 ± 14 mmHg, t(13) = 2.44 p < 0.05, |d|= 0.55) but not normoxia (154 ± 22 vs. 150 ± 16 mmHg, t(14) = 0.75, p = 0.46, |d|= 0.18) with no difference between groups over time (F = 0.08, p = 0.77, η2 = 0.01).
Conclusion: In old individuals hypoxia in addition to exercise does not have superior effects on office or exercise blood pressure compared to training in normoxia
Character of the stresses near the edge of the contact surface of a twisted anisotropic composite bar
On the existence of stress concentrations in loaded bodies made of polycrystalline materials
Consistency of the regression estimator with functional data under long memory conditions
International audienceWe study the nonparametric regression estimation when the explanatory variable takes values in some abstract functional space. We establish some asymptotic results and we give the (pointwise and uniform) convergence of the kernel type estimator constructed from functional data under long memory conditions