Flow Fragmentalism

In this paper, we articulate a version of non-standard A-theory – which we call Flow Fragmentalism – in relation to its take on the issue of supervenience of truth on being. According to the Truth Supervenes on Being (TSB) Principle, the truth of past- and future-tensed propositions supervenes, respectively, on past and future facts. Since the standard presentist denies the existence of past and future entities and facts concerning them that do not obtain in the present, she seems to lack the resources to accept both past and future-tensed truths and the TSB Principle. Contrariwise, positions in philosophy of time that accept an eternalist ontology (e.g., B-theory, moving spotlight, and Fine’s and Lipman’s versions of fragmentalism) allow for a “direct” supervenience base for past- and future-tensed truths. We argue that Flow Fragmentalism constitutes a middle ground, which retains most of the advantages of both views, and allows us to articulate a novel account of the passage of time

On the Cognition of States of Affairs

The theory of speech acts put forward by Adolf Reinach in his "The A Priori Foundations of the Civil Law" of 1913 rests on a systematic account of the ontological structures associated with various different sorts of language use. One of the most original features of Reinach's account lies in hIs demonstration of how the ontological structure of, say, an action of promising or of commanding, may be modified in different ways, yielding different sorts of non-standard instances of the corresponding speech act varieties. The present paper is an attempt to apply this idea of standard and modified instances of ontological structures to the realm of judgement and cognition, and thereby to develop a Reinachian theory of how intentionality is mediated through language in acts of thinking and speaking

Data Supply Chain (DSC): development and validation of a measurement instrument

The volume and availability of data produced and affordably stored has become an important new resource for building organizational competitive advantage. Reflecting this, and expanding the concept of the supply chain, we propose the Data Supply Chain (DSC) as a novel concept to aid investigations into how the interconnected data characteristics relate to and impact organizational performance. Initially, we define the concept and develop a research agenda on DSC coupling theoretical background of strategy and operations literature. Along with the conceptualization, we develop a set of propositions and make suggestions for future research including testing and validating the model fit

Contribution of cod liver oil-related nutrients (vitamins A, D, E and eicosapentaenoic acid and docosahexaenoic acid) to daily nutrient intake and their associations with plasma concentrations in the EPIC-Norfolk cohort

Total nutrient intake (TNI) is intake from food and supplements. This provides an assessment of nutrient adequacy and the prevalence of excessive intake, as well as the response with respect to biomarkers. Cod liver oil (CLO) is the most frequently consumed supplement in the UK, containing nutrients that might have varying influences on health. We calculated TNI for vitamins A, D and E, as well as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and assessed associations with the respective blood concentrations

Hydrogen Enriched Natural Gas as a Clean Motor Fuel (CONTINUATION OF 7863 ABANDONED)

A fuel mixture is disclosed. In a preferred embodiment, an alternative gaseous fuel for operating a combustion engine includes approximately 21 to 50% Hydrogen and the rest natural gas constituants such as combinations of Methane, Carbon Dioxide, Nitrogen, Ethane, Propane, Iso-Butane, N-Butane, Iso Pentane, N-Pentane, and Hexanes Plus. Current production engines without any substantial modifications can take this alternative fuel. This alternative fuel is lean burning and emits emissions that are below current legal standards

Hydrogen Enriched Natural Gas as a Motor Fuel with variable Air Fuel Ratio and Fuel Mixture Ratio Control (CIP OF 7863 ABANDONED)

A hydrogen and natural gas fuel mixture for internal combustion engines is provided for vehicle engines such as those used in standard production engines for automobiles, trains and lawn mowers. The gaseous fuel for operating a vehicle combustion engines includes approximately 21 to 50% Hydrogen and the rest natural gas constituents such as combinations of Methane, Carbon Dioxide, Nitrogen, Ethane, Propane, Iso-Butane, N-Butane, Iso Pentane, N-Pentane, and Hexanes Plus. A fuel mixture of approximately 28 to 36 percent Hydrogen and a air fuel equivalence ratio of approximately 0.625 is an extreme lean burn condition that yields hydrocarbon emission levels of less than approximately 104 ppm (0.84 hm/hp hr.). Current internal combustion engines that are in mass production can take this alternative fuel without any substantial modifications to their systems. This alternative fuel is lean burning and emits emissions that are below current legal standards. The novel fuel mixture can be use

Hydrogen Enriched Natural Gas as a Motor Fuel with Variable Air Fuel Ratio and Fuel Mixture Ratio Control (DIV OF 6637 and CIP OF 7863)

A hydrogen and natural gas fuel mixture for internal combustion engines is provided for vehicle engines such as those used in standard production engines for automobiles, trains and lawn mowers. The gaseous fuel for operating a vehicle combustion engines includes approximately 21 to 50% Hydrogen and the rest natural gas constituents such as combinations of Methane, Carbon Dioxide, Nitrogen, Ethane, Propane, Iso-Butane, N-Butane, Iso Pentane, N-Pentane, and Hexanes Plus. A fuel mixture of approximately 28 to 36 percent Hydrogen and a air fuel equivalence ratio of approximately 0.625 is an extreme lean burn condition that yields hydrocarbon emission levels of less than approximately 104 ppm (0.84 hm/hp hr.). Current internal combustion engines that are in mass production can take this alternative fuel without any substantial modifications to their systems. This alternative fuel is lean burning and emits emissions that are below current legal standards. The novel fuel mixture can be use

Phagocytes and the Lung

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72927/1/j.1749-6632.1997.tb46258.x.pd

Identification of two distinct intron elements involved in alternative splicing of beta-tropomyosin pre-mRNA

The rat beta-tropomyosin gene encodes two isoforms, termed skeletal muscle beta-tropomyosin and fibroblast last tropomyosim 1 (TM-1), via an alternative RNA processing mechanism. The gene contains 11 exons. Exons 1-5 and exons 8 and 9 are common to all mRNAs expressed from the gene. Exons 6 and 11 are used in fibroblasts, as well as smooth muscle, whereas exons 7 and 10 are used only in skeletal muscle. In the present studies we focused on the mutually exclusive internal alternative splice choice involving exon 6 (fibroblast-type splice) and exon 7 (skeletal muscle-type splice). We have identified two distinct elements in the intron, upstream of exon 7, involved in splice site selection. The first element is comprised of a polypyrimidine tract located 89-143 nucleotides upstream of the 3' splice site, which specifies the location of the lariat branchpoints used, 144-153 nucleotides upstream of exon 7. The 3' splice site AG dinucleotide has no role in selection of these branchpoints. The second element is comprised of intron sequences located between the polypyrimidine tract and the 3' splice site of exon 7. It contains an important determinant in alternative splice site selection, because deletion of these sequences results in the use of the skeletal muscle-specific exon in nonmuscle cells. We propose that the use of lariat branchpoints located far upstream from a 3' splice site may be a general feature of some alternatively excised introns, reflecting the presence of regulatory sequences located between the lariat branch site and the 3' splice site. The data also indicate that alternative splicing of the rat beta-tropomyosin gene is regulated by a somewhat different mechanism from that described for rat alpha-tropomyosin gene and the transformer-2 gene of Drosophila melanogaster