Agamic Pscyhology, Social Interaction and Learning.*

Dalam rencana ini ada diteranglcan suatu teori pembelajaran baru yang dibentuk dengan menggunakan idea-idea psikologi negara-negara Asia. Ada ditafsirkan bahawa pembelajaran ialah jenis tingkahlaku atau tindakan untuk mengurangkan kejahilan. Proses pembelajaran juga dibahagikan kepada tiga jenis: pembelajaran (' ~ dan -~ . Pembelajaran ~ ialah hampir sama dengan pembelajaran instrumental yang telah dikaji oleh ahli-ahli psikologi behaviorisma. Pembelajaran {3 ialah pembelajaran mengenai diri sendiri, di mana beberapa tindakan dilakukan untuk mendapat kefahaman mendalam mengenai diri sendiri. Pembelajaran ·(l ialah pembelajaran jenis berbentuk ugama atau falsafah. Teori pembelajaran ini juga dikaitkan kepada suatu teori penanggapan yang hampir sama dengan teori penanggapan Ciestalt. Tetapi dalam teori ini, penanggapan menyeluruh mengenai dunia, kehidupan dan sebagainya (dipanggil T-URU) ditekanKan kerana 1nilah yang menentukan sikap-sikap 'moral' seseorang dalam kehidupan seharian

Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model

Ovarian cancer is the leading cause of cancer related deaths in women. Genetic alterations including overexpression of EGFR play a crucial role in ovarian carcinogenesis. Here we evaluated the effect of phenethyl isothiocyanate (PEITC) in ovarian tumor cells in vitro and in vivo. Oral administration of 12 μmol PEITC resulted in drastically suppressing ovarian tumor growth in a preclinical mouse model. Our in vitro studies demonstrated that PEITC suppress the growth of SKOV-3, OVCAR-3 and TOV-21G human ovarian cancer cells by inducing apoptosis in a concentration-dependent manner. Growth inhibitory effects of PEITC were mediated by inhibition of EGFR and AKT, which are known to be overexpressed in ovarian tumors. PEITC treatment caused significant down regulation of constitutive protein levels as well as phosphorylation of EGFR at Tyr1068 in various ovarian cancer cells. In addition, PEITC treatment drastically reduced the phosphorylation of AKT which is downstream to EGFR and disrupted mTOR signaling. PEITC treatment also inhibited the kinase activity of AKT as observed by the down regulation of p-GSK in OVCAR-3 and TOV-21G cells. AKT overexpression or TGF treatment blocked PEITC induced apoptosis in ovarian cancer cells. These results suggest that PEITC targets EGFR/AKT pathway in our model. In conclusion, our study suggests that PEITC could be used alone or in combination with other therapeutic agents to treat ovarian cancer. © 2012 Loganathan et al

Influence of Panchagavya foliar spray on the growth attributes and yield of baby corn (Zea mays) cv. COBC 1

Field experiments were conducted at experimental farm, Faculty of Agriculture, Annamalai University, Chidambaram during July to September (2008) and January to March (2009) in two seasons to study the effect of foliar spray of Panchagavya on the growth and yield of Baby corn cv. COBC 1. The experiments were laid out in Randomized Block Design with fourteen treatments and replicated thrice. The treatments included foliar spray and inorganic nutrient application at various stages of baby corn. The results revealed that application of 100% recommended dose of fertilizers (RDF) [N150: P60 (P2O5): K40 (K2O)] and 4 sprays (15, 25, 35 and 45 DAS) of 3 % Panchagavya recorded the highest growth attributes and yield of fresh Baby corn and this was followed by application of recommended dose of fertilizers (100 %) along with 3 sprays (15, 25 and 35 DAS) of 3 % panchagavya during both the seasons. The least growth and yield parameter were recorded in 3 sprays of 4 % Panchagavya without use of inorganic fertilizers. The increase in growth and yield of baby corn was mainly attributed by greater availability of nutrients through soil application (100 % RDF) and foliar spray of panchagavya at various stages of crop growth

Heat and mass transfer analysis of casson fluid flow on a permeable riga-plate

79-86Numerical analysis has been carried out for a casson fluid flow on a riga-plate with temperature dependent thermal conductivity. The physical model which governs the transport properties is solved numerically. This investigation emphasizes the consequence of variable thermal conductivity and electrically conducting magnetic field on the fluid flow. Rate of heat transfer is elevated, while the flow exposed to constructive case of variable thermal conductivity. The flow speed is enhanced for the improved values of modified Hartmann number. Correlation of the results with the similarity solutions declares the accuracy

Inquiry of inclined magnetic field effects on Walter –B nanofluid flow with heat generation / absorption

The article deals with Walter-B nanoliquid flow towards a extending surface with inclined magnetic field effects. Thermal relaxation analysis is made by non fourier heat flux model. Radiation, heat generation / absorption impacts are included. The non linear Partial governing systems are rebuild into nonlinear ordinary systems with the assist of proper similarity transformations. The graphical results are portrayed for velocity, concentration and temperature profile. The physical entitles of heat and mass transfer rates are graphically reported. The comparission with previous results notified the excellent agreement

Noninvasive index using complete blood counts (P2/MS) for detecting oesophageal varices in cirrhosis

BACKGROUND: The diagnosis of EV is required for patients with liver cirrhosis to detect those who will benefit from variceal bleeding primary prophylaxis. Currently, esophago-gastro-duodenoscopy (EGD) remains the gold standard test for such diagnosis. However, EGD is limited by its invasiveness and high cost. A simple non-invasive widely available and cheap test would be ideal if proved to have sufficient specificity and sensitivity. Therefore, aim of this study is the diagnostic value of an index derived from the patients' complete blood count; namely the P2/MS ratio as a predictive tool for the presence of varices and if they are at high risk of bleeding. AIMS & OBJECTIVES: 1. To evaluate the predictive value of P2/MS index (platelet count)2/[monocyte fraction (%) × segmented neutrophil fraction (%)] derived from the patient's complete blood count for detecting oesophageal varices in cirrhosis. 2. To compare the P2/MS index in cirrhosis patients with portal hypertension and patients without portal hypertension STUDY POPULATION: This study was conducted in 50 patients with liver cirrhosis attending the Department of Medicine and Department of Medical gastroenterology, Govt. Rajaji Hospital, Madurai METHODS: 50 liver cirrhosis patients with no previous variceal bleeding and not on beta blocker prophylaxis were subjected to do complete blood count test. P2/MS index were calculated using platelet count, monocyte fraction and neutrophil fraction. They were subjected to esophagogastroduodenoscopy for detecting esophageal varices and comparing p2/ms index in cirrhosis patients with portal hypertension and patients without portal hypertension RESULTS: Out of 50 patients ogd findings were normal in 22 patients with median p2/ms index of 147,grade I varices in 9 patients with median p2/ms index of 42,grade II varices in 12 patients with median p2/ms index of 35.5,and grade III varices in 7 patients with median p2/ms index of 21 In patients with portal hypertension the median p2/ms index was 36 where as in patients without portal hypertension the median p2/ms index was 138. Among 50 cirrhosis patients ogd findings were normal in 22 patients with median p2/ms index of 147. In this study. above a cut-off value for P2/MS of 30.5, high risk esophageal varices could be excluded, with a negative predictive value [NPV] of 91.6%. CONCLUSION: In patients with low p2/ms index esophageal varices are more likely present and it has emerged as significant predictors for the presence of esophageal varices in cirrhosis patient. P2/ms index was low in patients with portal hypertension when compared to patients without portal hypertensio

Newtonian Heating Effects of Oldroyd-B Liquid Flow with Cross-Diffusion and Second Order Slip

The current study highlights the Newtonian heating and second-order slip velocity with cross-diffusion effects on Oldroyd-B liquid flow. The modified Fourier heat flux is included in the energy equation system. The present problem is modeled with the physical governing system. The complexity of the governing system was reduced to a nonlinear ordinary system with the help of suitable transformations. A homotopy algorithm was used to validate the nonlinear system. This algorithm was solved via MATHEMATICA software. Their substantial aspects are further studied and reported in detail. We noticed that the influence of slip velocity order two is lower than the slip velocity order one

Effect of soaking time and concentration of NaOH solution on mechanical properties of coir-polyester composites

The green husk coir fibres were treated with different levels of soaking time and concentration of alkali solution. As a result of alkali treatment, the surface modifications were done on the fibre surface and were studied using scanning electron micrographs. The coir–polyester composites were fabricated using hand lay up process and the mechanical properties (tensile, flexural and impact strength) were evaluated as per ASTM standards. The effect of soaking time and concentration of NaOH solution were studied based on evaluated values of mechanical properties to find out optimum fibre treatment parameters

Antioxidant and Antiproliferative Effect of Pleurotus ostreatus

In this study, ethanol extract of an edible mushroom Pleurotus ostreatus cultivated under the laboratory condition was investigated for its antioxidant and anticancer property in vitro. To confirm the total antioxidant activity, ABTS, DPPH free radical-scavenging assay was carried, along with total phenolic and flavonoid concentration. The ethanolic extract showed a potent antioxidant activity against both DPPH and ABTS radicals, with the EC50 value of 0.202±0.55 mg/mL and 6.42±0.261 mg/mL. Antioxidant components like total flavonoids were 1.82±0.15 µg/mg (Quercetin equivalent) and the total phenols were 8.52±0.6 mg/g (Catechin equivalent). Against the cancer cell (HL-60) in vitro P. ostreatus extracts exhibited the cytotoxic effect. The HL-60 cells treated with ethanol extract was further stained with propidium iodide and analyzed through flow cytometry, to identify whether the cytotoxicity induction was due to apoptosis or necrocis. The results of the flow cytometry confirm the cytotoxic effect of the mushroom extract was found to be mediated by the induction of apoptosis. In conclusion, our results supported the consumption of edible mushroom that act as a good dietary supplement and functional food

Computational analysis of third-grade liquid flow with cross diffusion effects: application to entropy modeling

The key goal of this current study is to analyze the entropy generation with cross diffusion effects. The third-grade type non-Newtonian fluid model is used in this study. The current flow problem is modelled with stretching plate. Modified Fourier heat flux is replaced the classical heat flux. The appropriate transformation is availed to convert the basic boundary layers equations into ODEs and then verified by homotopy algorithm. The consequences of various physical quantities on temperature, velocity, entropy and concentration profile are illustrated graphically