Disparities in Cause-Specific Cancer Survival by Census Tract Poverty Level in Idaho, U.S.

Objective. This population-based study compared cause-specific cancer survival by socioeconomic status using methods to more accurately assign cancer deaths to primary site. Methods. The current study analyzed Idaho data used in the Accuracy of Cancer Mortality Statistics Based on Death Certificates (ACM) study supplemented with additional information to measure cause-specific cancer survival by census tract poverty level. Results. The distribution of cases by primary site group differed significantly by poverty level (chi-square = 265.3, 100 df, p In the life table analyses, for 8 of 24 primary site groups investigated, and all sites combined, there was a significant gradient relating higher poverty with poorer survival. For all sites combined, the absolute difference in 5-year cause-specific survival rate was 13.6% between the lowest and highest poverty levels. Conclusions. This study shows striking disparities in cause-specific cancer survival related to the poverty level of the area a person resides in at the time of diagnosis

Massive M2M Access with Reliability Guarantees in LTE Systems

Machine-to-Machine (M2M) communications are one of the major drivers of the cellular network evolution towards 5G systems. One of the key challenges is on how to provide reliability guarantees to each accessing device in a situation in which there is a massive number of almost-simultaneous arrivals from a large set of M2M devices. The existing solutions take a reactive approach in dealing with massive arrivals, such as non-selective barring when a massive arrival event occurs, which implies that the devices cannot get individual reliability guarantees. In this paper we propose a proactive approach, based on a standard operation of the cellular access. The access procedure is divided into two phases, an estimation phase and a serving phase. In the estimation phase the number of arrivals is estimated and this information is used to tune the amount of resources allocated in the serving phase. Our results show that the proactive approach is instrumental in delivering high access reliability to the M2M devices.Comment: Accepted for presentation in ICC 201

Random Access for Machine-Type Communication based on Bloom Filtering

We present a random access method inspired on Bloom filters that is suited for Machine-Type Communications (MTC). Each accessing device sends a \emph{signature} during the contention process. A signature is constructed using the Bloom filtering method and contains information on the device identity and the connection establishment cause. We instantiate the proposed method over the current LTE-A access protocol. However, the method is applicable to a more general class of random access protocols that use preambles or other reservation sequences, as expected to be the case in 5G systems. We show that our method utilizes the system resources more efficiently and achieves significantly lower connection establishment latency in case of synchronous arrivals, compared to the variant of the LTE-A access protocol that is optimized for MTC traffic. A dividend of the proposed method is that it allows the base station (BS) to acquire the device identity and the connection establishment cause already in the initial phase of the connection establishment, thereby enabling their differentiated treatment by the BS.Comment: Accepted for presentation on IEEE Globecom 201

EarthN: A new Earth System Nitrogen Model

The amount of nitrogen in the atmosphere, oceans, crust, and mantle have important ramifications for Earth's biologic and geologic history. Despite this importance, the history and cycling of nitrogen in the Earth system is poorly constrained over time. For example, various models and proxies contrastingly support atmospheric mass stasis, net outgassing, or net ingassing over time. In addition, the amount available to and processing of nitrogen by organisms is intricately linked with and provides feedbacks on oxygen and nutrient cycles. To investigate the Earth system nitrogen cycle over geologic history, we have constructed a new nitrogen cycle model: EarthN. This model is driven by mantle cooling, links biologic nitrogen cycling to phosphate and oxygen, and incorporates geologic and biologic fluxes. Model output is consistent with large (2-4x) changes in atmospheric mass over time, typically indicating atmospheric drawdown and nitrogen sequestration into the mantle and continental crust. Critical controls on nitrogen distribution include mantle cooling history, weathering, and the total Bulk Silicate Earth+atmosphere nitrogen budget. Linking the nitrogen cycle to phosphorous and oxygen levels, instead of carbon as has been previously done, provides new and more dynamic insight into the history of nitrogen on the planet.Comment: 36 pages, 12 figure

Early Dark Energy with Power-law F(R) Gravity

We study a power-law $F(R)$ gravity with an early dark energy term, that can describe both the early-time and the late-time acceleration of the Universe. We confront this scenario with recent observational data including the Pantheon Type Ia supernovae, measurements of the Hubble parameter $H(z)$ (Cosmic Chronometers), data from Baryon Acoustic Oscillations and standard rulers data from the Cosmic Microwave Background (CMB) radiation. The model demonstrates some achievements in confronting with these observations and can be compared with the $\Lambda$-Cold-Dark-Matter model. In particular, in both models we obtain very close estimates for the Hubble constant $H_0$, but it is not true for $\Omega_m^0$. The early dark energy term supports viability of the considered $F(R)$ gravity model.Comment: PLB Accepte

The Use Of Oral Ranolazine To Convert New Or Paroxysmal Atrial Fibrillation: A Review Of Experience With Implications For Possible "Pill In The Pocket" Approach To Atrial Fibrillation

Background: Atrial fibrillation (AF) is the most common arrhythmia requiring treatment. High dose oral anti-arrhythmics may cardiovert some paroxysmal AF. This "pill in pocket" approach has allowed patients to treat themselves on an as needed basis. Pro-arrhythmic concerns have limited the usefulness of this approach to patients without structural heart disease. Ranolazine is an anti-anginal agent, which inhibits abnormal late Na+ channel currents in cardiomyocytes and decreases sodium-calcium overload. Ranolazine is a potent inhibitor of after-depolarizations, which have been implicated in the initiation and propagation of AF. Because ranolazine has no known pro-arrhythmic effects, it could be useful as a safe "pill in the pocket" agent if it were effective in converting AF. We describe our experience using oral ranolazine to convert new or paroxysmal AF. Method: 2000 mg of ranolazine were administered to 18 patients with new (11 patients) or paroxysmal (7 patients) AF of at least 3, but not greater than 48 hours duration. Most patients (14) were in the hospital at the time ranolazine was administered. Age, sex, echocardiographic data, associated health conditions and structural heart disease were recorded. Successful conversion was defined as restoring sinus rhythm within 6 hours of ranolazine administration. Results: All but 1 patient had some form of structural heart disease and all but 2 patients had left atrial enlargement. Thirteen of 18 patients converted to sinus rhythm. No pro-arrhythmic effects, hemodynamic instability, adverse rate effects, or perceived intolerance (other than constipation) were noted. The 72% conversion rate was comparable to other reported "pill in the pocket" protocols. Conclusion: High dose oral ranolazine shows utility as a possible safe agent to convert new or paroxysmal AF. Lack of blinded controls and small numbers limits the power of this observation

Closing the expectation gap between employees and their supervisors

In an effort to address a growing issue between working relationships (employee vs. employer, co-worker vs. co-worker, family vs. family) with regard to how expectations of job performances, team assignments and basic human interaction are being affected, particularly as it relates to the quality and depth of such relationships, this report will attempt to determine what factors contribute to this issue and offer specific recommendations toward reducing and/or minimizing this growing problem

Engaging without over-powering: A case study of a FLOSS project

This is the post-print version of the published chapter. The original publication is available at the link below. Copyright @ 2010 IFIP International Federation for Information Processing.The role of Open Source Software (OSS) in the e-learning business has become more and more fundamental in the last 10 years, as long as corporate and government organizations have developed their educational and training programs based on OSS out-of-the-box tools. This paper qualitatively documents the decision of the largest UK e-learning provider, the Open University, to adopt the Moodle e-learning system, and how it has been successfully deployed in its site after a multi-million investment. A further quantitative study also provides evidence of how a commercial stakeholder has been engaged with, and produced outputs for, the Moodle community. Lessons learned from this experience by the stakeholders include the crucial factors of contributing to the OSS community, and adapting to an evolving technology. It also becomes evident how commercial partners helped this OSS system to achieve the transition from an “average” OSS system to a successful multi-site, collaborative and community-based OSS project